Expression and function of Slc34 sodium–phosphate co-transporters in skeleton and teeth

Abstract : Under normal physiological condition, the biomineralization process is limited to skeletal tissues and teeth and occurs throughout the individual's life. Biomineralization is an actively regulated process involving the progressive mineralization of the extracellular matrix secreted by osteoblasts in bone or odontoblasts and ameloblasts in tooth. Although the detailed molecular mechanisms underlying the formation of calcium-phosphate apatite crystals are still debated, it is suggested that calcium and phosphate may need to be transported across the membrane of the mineralizing cell, suggesting a pivotal role of phosphate transporters in bone and tooth mineralization. In this context, this short review describes the current knowledge on the role of Slc34 Na+-phosphate transporters in skeletal and tooth mineralization.
Type de document :
Article dans une revue
Pflügers Archiv European Journal of Physiology, Springer Verlag (Germany), 2018, Epub ahead of print. 〈10.1007/s00424-018-2240-y〉
Liste complète des métadonnées

https://www.hal.inserm.fr/inserm-01945854
Contributeur : Valérie Pecqueret <>
Soumis le : jeudi 6 décembre 2018 - 15:33:48
Dernière modification le : vendredi 7 décembre 2018 - 08:15:31

Fichier

 Accès restreint
Fichier visible le : jamais

Connectez-vous pour demander l'accès au fichier

Identifiants

Collections

Citation

Laurent Beck. Expression and function of Slc34 sodium–phosphate co-transporters in skeleton and teeth. Pflügers Archiv European Journal of Physiology, Springer Verlag (Germany), 2018, Epub ahead of print. 〈10.1007/s00424-018-2240-y〉. 〈inserm-01945854〉

Partager

Métriques

Consultations de la notice

31