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Journal Articles Nanotechnology Year : 2011

Control of neuronal network organization by chemical surface functionalization of multi-walled carbon nanotube arrays.

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Abstract

Carbon nanotube substrates are promising candidates for biological applications and devices. Interfacing of these carbon nanotubes with neurons can be controlled by chemical modifications. In this study, we investigated how chemical surface functionalization of multi-walled carbon nanotube arrays (MWNT-A) influences neuronal adhesion and network organization. Functionalization of MWNT-A dramatically modifies the length of neurite fascicles, cluster inter-connection success rate, and the percentage of neurites that escape from the clusters. We propose that chemical functionalization represents a method of choice for developing applications in which neuronal patterning on MWNT-A substrates is required.
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Dates and versions

inserm-00587525 , version 1 (20-04-2011)

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Jie Liu, Florence Appaix, Olivier Bibari, Gilles Marchand, Alim-Louis Benabid, et al.. Control of neuronal network organization by chemical surface functionalization of multi-walled carbon nanotube arrays.. Nanotechnology, 2011, 22 (19), pp.195101. ⟨10.1088/0957-4484/22/19/195101⟩. ⟨inserm-00587525⟩
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