Autophagy in health and disease: focus on the cardiovascular system - Archive ouverte HAL Access content directly
Journal Articles Essays in Biochemistry Year : 2017

Autophagy in health and disease: focus on the cardiovascular system

(1) , (1)
1

Abstract

Autophagy is a highly conserved mechanism of lysosome-mediated protein and organelle degradation that plays a crucial role in maintaining cellular homeostasis. In the last few years, specific functions for autophagy have been identified in many tissues and organs. In the cardiovascular system, autophagy appears to be essential to heart and vessel homeostasis and function; however defective or excessive autophagy activity seems to contribute to major cardiovascular disorders including heart failure (HF) or atherosclerosis. Here, we review the current knowledge on the role of cardiovascular autophagy in physiological and pathophysiological conditions.
Not file

Dates and versions

inserm-03904093 , version 1 (16-12-2022)

Identifiers

Cite

Jeanne Mialet-Perez, Cécile Vindis. Autophagy in health and disease: focus on the cardiovascular system. Essays in Biochemistry, 2017, 61 (6), pp.721-732. ⟨10.1042/EBC20170022⟩. ⟨inserm-03904093⟩
0 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More