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Journal Articles Tropical Medicine and Infectious Disease Year : 2021

Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali

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Abstract

In Mali, since 2007, artemether-lumefantrine has been the first choice against uncomplicated malaria. Despite its effectiveness, a rapid selection of markers of resistance to partner drugs has been documented. This work evaluated the treatment according to the World Health Organization's standard 28-day treatment method. The primary endpoint was the clinical and parasitological response corrected by a polymerase chain reaction. It was more than 99.9 percent, the proportion of patients with anemia significantly decrease compared to baseline (p < 0.001), and no serious events were recorded. Plasmodium falciparum remains sensitive to artemether-lumefantrine in Mali.
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inserm-03832308 , version 1 (27-10-2022)

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Modibo Diarra, Drissa Coulibaly, Amadou Tapily, Boureima Guindo, Koualy Sanogo, et al.. Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali. Tropical Medicine and Infectious Disease, 2021, 6 (1), pp.13. ⟨10.3390/tropicalmed6010013⟩. ⟨inserm-03832308⟩

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