Skip to Main content Skip to Navigation
Journal articles

History of bariatric surgery and COVID-19 outcomes in patients with type 2 diabetes: Results from the CORONADO study

Claire Blanchard 1, 2 T. Perennec 3 S. Smati 2 B. Tramunt 4 B. Guyomarch 2 E. Bigot-Corbel 5 L. Bordier S. Borot 6 O. Bourron 7 C. Caussy 8, 9 C. Coffin-Boutreux 10 A. Dutour 11 N. Germain 12, 13 C. Gonfroy-Leymarie 14 L. Meyer 15 G. Prevost 16, 17 R. Roussel 7 D. Seret-Begue 18 C. Thivolet 9 B. Vergès 19, 20 M. Pichelin 21, 2 P. Gourdy 22 S. Hadjadj 21, 2 M. Wargny 3, 2 F. Pattou 23, 24, 25 B. Cariou 21, 2 
Abstract : OBJECTIVE: This study assessed the impact of a history of metabolic and bariatric surgery (MBS) on the clinical outcomes in patients with type 2 diabetes (T2D) and severe obesity hospitalized for COVID-19. METHODS: In this post hoc analysis from the nationwide observational CORONADO (Coronavirus SARS-CoV2 and Diabetes Outcomes) study, patients with T2D and a history of MBS were matched with patients without MBS for age, sex, and BMI either at the time of MBS or on admission for COVID-19. The composite primary outcome (CPO) combined invasive mechanical ventilation and/or death within 7 and 28 days following admission. RESULTS: Out of 2,398 CORONADO participants, 20 had a history of MBS. When matching for BMI at the time of MBS and after adjustment for diabetes duration, the CPO occurred less frequently within 7 days (3 vs. 17 events, OR: 0.15 [0.01 to 0.94], p = 0.03) and 28 days (3 vs. 19 events, OR: 0.11 [0.01 to 0.71], p = 0.02) in patients with MBS (n = 16) vs. controls (n = 44). There was no difference in CPO rate between patients with MBS and controls when matching for BMI on admission. CONCLUSIONS: These data are reassuring regarding COVID-19 prognosis in patients with diabetes and a history of MBS compared with those without MBS.
Document type :
Journal articles
Complete list of metadata
Contributor : laboratoire CarMeN Connect in order to contact the contributor
Submitted on : Friday, August 19, 2022 - 12:09:53 PM
Last modification on : Wednesday, September 7, 2022 - 3:51:22 AM


 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document



Claire Blanchard, T. Perennec, S. Smati, B. Tramunt, B. Guyomarch, et al.. History of bariatric surgery and COVID-19 outcomes in patients with type 2 diabetes: Results from the CORONADO study. Obesity, Wiley, 2022, 30 (3), pp.599-605. ⟨10.1002/oby.23314⟩. ⟨inserm-03754180⟩



Record views