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Adipocyte extracellular vesicles: new rescuers of mitochondrial stress in the heart

Abstract : Nutrient excess induces mitochondrial dysfunction which participates to obesityrelated complications. Obesity also associates with high cardiac oxidative stress that contributes to myocardial dysfunction. Crewe et al. recently evidenced the pivotal role of adipocyte-derived extracellular vesicles in cardiac oxidative stress responses and revealed their unexpected protective effect against ischemia/reperfusion injury.
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https://www.hal.inserm.fr/inserm-03620375
Contributor : Chantal Boulanger Connect in order to contact the contributor
Submitted on : Friday, March 25, 2022 - 6:20:45 PM
Last modification on : Friday, August 5, 2022 - 11:56:21 AM
Long-term archiving on: : Sunday, June 26, 2022 - 7:10:55 PM

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Xavier Loyer, Chantal Boulanger, Soazig Le Lay. Adipocyte extracellular vesicles: new rescuers of mitochondrial stress in the heart. Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , Elsevier, 2022, 33 (1), pp.1-3. ⟨10.1016/j.tem.2021.11.001⟩. ⟨inserm-03620375⟩

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