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Dual Ureaplasma parvum arthritis: a case report of U. parvum septic arthritis following contralateral reactive arthritis in an immunosuppressed patient

Abstract : Background: Ureaplasma parvum is usually part of the normal genital flora. Rarely can it cause invasive infections such as genitourinary infections, septic arthritis, or meningitis. Case presentation: Here we present the first description of chronic ureterocystitis in a 56-year-old immunocompromised patient, complicated first by reactive arthritis and secondarily by contralateral septic arthritis due to U. parvum infection. U. parvum was detected in synovial fluid and in a urine sample. Treatment consisted of double-J stenting and targeted antibiotic therapy. Evolution showed resolution of urinary symptoms and clinical improvement of arthritis despite functional sequelae. Conclusions: Given the high prevalence of U. parvum colonisation, this diagnosis should remain a diagnosis of exclusion. However, because of the difficulty in detecting this microorganism, it should be considered in unexplained subacute urethritis or arthritis, including reactive arthritis, especially in immunosuppressed patients. Real-time PCR positivity in the absence of a differential diagnosis should not be overlooked.
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https://www.hal.inserm.fr/inserm-03555515
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Submitted on : Thursday, February 3, 2022 - 4:26:57 PM
Last modification on : Friday, February 4, 2022 - 3:55:29 AM
Long-term archiving on: : Wednesday, May 4, 2022 - 8:33:04 PM

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Lea Lemoine, Cecile Le Brun, Francois Maillot, Camille Thorey, Annaelle Boucaud, et al.. Dual Ureaplasma parvum arthritis: a case report of U. parvum septic arthritis following contralateral reactive arthritis in an immunosuppressed patient. BMC Infectious Diseases, BioMed Central, 2021, 21 (1), pp.1117. ⟨10.1186/s12879-021-06733-0⟩. ⟨inserm-03555515⟩

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