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Amputation of a type II diabetic patient with cutaneous leishmaniasis due to Leishmania major

Abstract : Background: Leishmaniases are neglected tropical diseases of public health concern in Algeria. The immunocompromised patients with HIV, autoimmune diseases, or chronic alcohol abuse are at a higher risk of leishmaniasis. Herein, we present the case of an immunocompetent diabetic patient infected by Leishmania major, leading to lifethreatening consequences. Case presentation: An Algerian diabetic patient developed a cutaneous lesion with large polymorphous inflamed granuloma and pyoderma gangrenosum in the left foot, following L. major infection. A delayed follow-up led to a treatment failure, resulting in the amputation. Conclusions: This report highlights the absence of timely treatment of Leishmania infection as a life-threatening point among high-risk diabetic patients. Clinicians should be aware of this parasitosis leading to severe complications in diabetic patients.
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https://www.hal.inserm.fr/inserm-03555486
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Submitted on : Thursday, February 3, 2022 - 4:16:15 PM
Last modification on : Friday, April 1, 2022 - 3:48:55 AM
Long-term archiving on: : Wednesday, May 4, 2022 - 8:31:14 PM

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Arezki Izri, Amina Bendjaballah-Laliam, Denis Sereno, Ihcene Kherachi Djenad, Zoubir Harrat, et al.. Amputation of a type II diabetic patient with cutaneous leishmaniasis due to Leishmania major. BMC Infectious Diseases, BioMed Central, 2021, 21 (1), pp.1227. ⟨10.1186/s12879-021-06909-8⟩. ⟨inserm-03555486⟩

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