Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS‐Flow Cytometry Working Group
Arjan Loosdrecht
(1)
,
Wolfgang Kern
(2)
,
Anna Porwit
(3)
,
Peter Valent
(4)
,
Sharham Kordasti
(5)
,
Eline Cremers
(6)
,
Canan Alhan
(1)
,
Carolien Duetz
(1)
,
Alan Dunlop
(7)
,
Willemijn Hobo
(8)
,
Frank Preijers
(8)
,
Orianne Wagner‐ballon
(9, 10)
,
Nicolas Chapuis
(11, 12)
,
Michaela Fontenay
(11, 12)
,
Peter Bettelheim
(13)
,
Lisa Eidenschink‐brodersen
(14)
,
Patricia Font
(15)
,
Ulrika Johansson
(16)
,
Michael Loken
(14)
,
Jeroen Marvelde
(17)
,
Sergio Matarraz
(18)
,
Kiyoyuki Ogata
(19)
,
Uta Oelschlaegel
(20)
,
Alberto Orfao
(18)
,
Katherina Psarra
(21)
,
Dolores Subirá
(22)
,
Denise Wells
(14)
,
Marie Béné
(23, 24)
,
Matteo Della Porta
(25, 26)
,
Kate Burbury
(27)
,
Frauke Bellos
(2)
,
Vincent Velden
(17)
,
Theresia Westers
(1)
,
Leonie Saft
(28)
,
Robin Ireland
(29)
1
Amsterdam UMC - Amsterdam University Medical Center
2 M2L - Munich Leukemia Laboratory [Munich, Germany]
3 Lund University [Lund]
4 Medizinische Universität Wien = Medical University of Vienna
5 King‘s College London
6 MUMC - Maastricht University Medical Centre
7 The Royal Marsden
8 Radboud University Medical Center [Nijmegen]
9 Hôpital Henri Mondor
10 IMRB - Institut Mondor de Recherche Biomédicale
11 Hôpital Cochin [AP-HP]
12 IC UM3 (UMR 8104 / U1016) - Institut Cochin
13 Ordensklinikum Linz Elisabethinen
14 HematoLogics, Inc. [Seattle, WA, USA]
15 Hospital General Universitario "Gregorio Marañón" [Madrid]
16 University Hospitals Bristol
17 Erasmus MC - Erasmus University Medical Center [Rotterdam]
18 Universidad de Salamanca
19 MRTC Japan - Metropolitan Research and Treatment Centre for Blood Disorders [Tokyo, Japan]
20 University Hospital Carl Gustav Carus [Dresden, Germany]
21 Evangelismos Athens General Hospital
22 Universidad de Guadalajara
23 CRCINA-ÉQUIPE 1 - Immunobiology of Human αβ and γδ T Cells and Immunotherapeutic Applications
24 CHU Nantes - Centre hospitalier universitaire de Nantes
25 Hunimed - Humanitas University [Milan]
26 IRCCS Milan - Istituto Clinico Humanitas [Milan]
27 University of Melbourne
28 Karolinska Institutet [Stockholm]
29 KCH - King's College Hospital
2 M2L - Munich Leukemia Laboratory [Munich, Germany]
3 Lund University [Lund]
4 Medizinische Universität Wien = Medical University of Vienna
5 King‘s College London
6 MUMC - Maastricht University Medical Centre
7 The Royal Marsden
8 Radboud University Medical Center [Nijmegen]
9 Hôpital Henri Mondor
10 IMRB - Institut Mondor de Recherche Biomédicale
11 Hôpital Cochin [AP-HP]
12 IC UM3 (UMR 8104 / U1016) - Institut Cochin
13 Ordensklinikum Linz Elisabethinen
14 HematoLogics, Inc. [Seattle, WA, USA]
15 Hospital General Universitario "Gregorio Marañón" [Madrid]
16 University Hospitals Bristol
17 Erasmus MC - Erasmus University Medical Center [Rotterdam]
18 Universidad de Salamanca
19 MRTC Japan - Metropolitan Research and Treatment Centre for Blood Disorders [Tokyo, Japan]
20 University Hospital Carl Gustav Carus [Dresden, Germany]
21 Evangelismos Athens General Hospital
22 Universidad de Guadalajara
23 CRCINA-ÉQUIPE 1 - Immunobiology of Human αβ and γδ T Cells and Immunotherapeutic Applications
24 CHU Nantes - Centre hospitalier universitaire de Nantes
25 Hunimed - Humanitas University [Milan]
26 IRCCS Milan - Istituto Clinico Humanitas [Milan]
27 University of Melbourne
28 Karolinska Institutet [Stockholm]
29 KCH - King's College Hospital
Peter Valent
- Function : Author
- PersonId : 759814
- ORCID : 0000-0003-0456-5095
Orianne Wagner‐ballon
- Function : Author
- PersonId : 756203
- ORCID : 0000-0001-9071-6683
- IdRef : 079569668
Nicolas Chapuis
- Function : Author
- PersonId : 768515
- ORCID : 0000-0003-0601-3948
- IdRef : 12957189X
Michaela Fontenay
- Function : Author
- PersonId : 770387
- ORCID : 0000-0002-5492-6349
- IdRef : 083817247
Ulrika Johansson
- Function : Author
- PersonId : 767741
- ORCID : 0000-0003-0743-7400
Alberto Orfao
- Function : Author
- PersonId : 759817
- ORCID : 0000-0002-0007-7230
Dolores Subirá
- Function : Author
- PersonId : 762164
- ORCID : 0000-0002-9485-0529
Marie Béné
- Function : Author
- PersonId : 767851
- ORCID : 0000-0002-6569-7414
Matteo Della Porta
- Function : Author
Vincent Velden
- Function : Author
- PersonId : 821107
- ORCID : 0000-0001-9457-3763
Abstract
This article discusses the rationale for inclusion of flow cytometry (FCM) in the diagnostic investigation and evaluation of cytopenias of uncertain origin and suspected myelodysplastic syndromes (MDS) by the European LeukemiaNet international MDS Flow Working Group (ELN iMDS Flow WG). The WHO 2016 classification recognizes that FCM contributes to the diagnosis of MDS and may be useful for prognostication, prediction, and evaluation of response to therapy and follow-up of MDS patients.
Fichier principal
Cytometry Part B Clinical - 2021 - Loosdrecht - Clinical application of flow cytometry in patients with unexplained.pdf (1.23 Mo)
Télécharger le fichier
Origin : Publication funded by an institution