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The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper

Grigoris Gerotziafas 1, 2 Mariella Catalano 3 yiannis Theodorou 4 Patrick Van Dreden 1 Vincent Marechal 1 Alex Spyropoulos 5 Charles Carter 6 Nusrat Jabeen 7 Job Harenberg 8 Ismail Elalamy 1, 5 Anna Falanga 9 Jawed Fareed 10 Petros Agathaggelou 11 Darko Antic 12 Pier Luigi Antignani 13 Manuel Monreal Bosch 14 Benjamin Brenner 15, 16 Vladimir Chekhonin 17 Mary-Paula Colgan 18, 19 Meletios-Athanasios Dimopoulos 20 Jim Douketis 21, 22 Essam Abo Elnazar 23 Katalin Farkas 24 Bahare Fazeli 25 Gerry Fowkes 26 yongquan Gu 27 Joseph Gligorov 1, 2, 28 Mark Ligocki 10 Tishya Indran 29 Meganathan Kannan 30 Bulent Kantarcioglu 31 Abdoul Aziz Kasse 32 Kostantinos Konstantinidis 33 Fabio Leivano 10 Joseph Lewis 34 Alexander Makatsariya 5 P Massamba Mbaye 35 Isabelle Mahé 36 Irina Panovska-Stavridis 37 Dan-Mircea Olinic 38 Chryssa Papageorgiou 39 Zsolt Pecsvarady 40 Sergio Pillon 41 Eduardo Ramacciotti 42, 43 Hikmat Abdel-Razeq 44 Michèle Sabbah 1, 28 Mouna Sassi 45 Gerit Schernthaner 46 Fakiha Siddiqui 10 Jin Shiomura 47 Anny Slama-Schwok 1, 28 Jean Claude Wautrecht 48 Alfonso Tafur 49 Ali Taher 50 Peter Klein-Wegel 51 Zenguo Zhai 52, 53 Tazi Mezalek Zoubida 54 
Abstract : Background One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and devastating public health crisis. Management Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success of these NPIs is dependent on the approval and commitment of the population. The launch of a mass vaccination program in many countries in late December 2020 with mRNA vaccines, adenovirus-based vaccines, and inactivated virus vaccines has generated hope for the end of the pandemic. Current Issues The continuous appearance of new pathogenic viral strains and the ability of vaccines to prevent infection and transmission raise important concerns as we try to achieve community immunity against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variants. The need of a second and even third generation of vaccines has already been acknowledged by the WHO and governments. Perspectives There is a critical and urgent need for a balanced and integrated strategy for the management of the COVID-19 outbreaks organized on three axes: (1) Prevention of the SARS-CoV-2 infection, (2) Detection and early diagnosis of patients at risk of disease worsening, and (3) Anticipation of medical care (PDA). Conclusion The “PDA strategy” integrated into state policy for the support and expansion of health systems and introduction of digital organizations (i.e., telemedicine, e-Health, artificial intelligence, and machine-learning technology) is of major importance for the preservation of citizens' health and life world-wide.
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Submitted on : Wednesday, November 24, 2021 - 4:26:02 PM
Last modification on : Tuesday, May 10, 2022 - 1:54:03 PM
Long-term archiving on: : Friday, February 25, 2022 - 7:38:01 PM


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Grigoris Gerotziafas, Mariella Catalano, yiannis Theodorou, Patrick Van Dreden, Vincent Marechal, et al.. The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper. Thrombosis and Haemostasis, Schattauer, 2021, 121 (08), pp.992-1007. ⟨10.1055/a-1535-8807⟩. ⟨inserm-03447118⟩



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