The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper
Grigoris Gerotziafas
(1, 2)
,
Mariella Catalano
(3)
,
Yiannis Theodorou
(4)
,
Patrick Van Dreden
(1)
,
Vincent Marechal
(1)
,
Alex Spyropoulos
(5)
,
Charles Carter
(6)
,
Nusrat Jabeen
(7)
,
Job Harenberg
(8)
,
Ismail Elalamy
(1, 5)
,
Anna Falanga
(9)
,
Jawed Fareed
(10)
,
Petros Agathaggelou
(11)
,
Darko Antic
(12)
,
Pier Luigi Antignani
(13)
,
Manuel Monreal Bosch
(14)
,
Benjamin Brenner
(15, 16)
,
Vladimir Chekhonin
(17)
,
Mary-Paula Colgan
(18, 19)
,
Meletios-Athanasios Dimopoulos
(20)
,
Jim Douketis
(21, 22)
,
Essam Abo Elnazar
(23)
,
Katalin Farkas
(24)
,
Bahare Fazeli
(25)
,
Gerry Fowkes
(26)
,
Yongquan Gu
(27)
,
Joseph Gligorov
(1, 2, 28)
,
Mark Ligocki
(10)
,
Tishya Indran
(29)
,
Meganathan Kannan
(30)
,
Bulent Kantarcioglu
(31)
,
Abdoul Aziz Kasse
(32)
,
Kostantinos Konstantinidis
(33)
,
Fabio Leivano
(10)
,
Joseph Lewis
(34)
,
Alexander Makatsariya
(5)
,
P Massamba Mbaye
(35)
,
Isabelle Mahé
(36)
,
Irina Panovska-Stavridis
(37)
,
Dan-Mircea Olinic
(38)
,
Chryssa Papageorgiou
(39)
,
Zsolt Pecsvarady
(40)
,
Sergio Pillon
(41)
,
Eduardo Ramacciotti
(42, 43)
,
Hikmat Abdel-Razeq
(44)
,
Michèle Sabbah
(1, 28)
,
Mouna Sassi
(45)
,
Gerit Schernthaner
(46)
,
Fakiha Siddiqui
(10)
,
Jin Shiomura
(47)
,
Anny Slama-Schwok
(1, 28)
,
Jean Claude Wautrecht
(48)
,
Alfonso Tafur
(49)
,
Ali Taher
(50)
,
Peter Klein-Wegel
(51)
,
Zenguo Zhai
(52, 53)
,
Tazi Mezalek Zoubida
(54)
1
CRSA -
Centre de Recherche Saint-Antoine
2 CHU Tenon [AP-HP]
3 UNIMI - Università degli Studi di Milano = University of Milan
4 CIMI - Centre d'Immunologie et des Maladies Infectieuses
5 Sechenov First Moscow State Medical University
6 CU - Campbell University [Buies Creek, NC, USA]
7 University of Karachi
8 Heidelberg University
9 UNIMIB - Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
10 Loyola University [Chicago]
11 CyI - Cyprus Institute
12 University of Belgrade [Belgrade]
13 NVC - Nuova Villa Claudia [Rome, Italy]
14 UCAM - Universidad Católica San Antonio de Murcia
15 Rambam Health Care Campus [Haifa, Israel]
16 Technion - Israel Institute of Technology [Haifa]
17 MHRF - Ministry of Health of the Russian Federation
18 St James's University Hospital
19 Trinity College Dublin
20 NKUA - National and Kapodistrian University of Athens
21 McMaster University [Hamilton, Ontario]
22 FIRH - Firestone Institute for Respiratory Health [Hamilton, ON, Canada]
23 Ministry of Health [Saudi Arabia]
24 SIH - Szent Imre Hospital [Budapest, Hungary]
25 Mashhad University of Medical Sciences
26 University of Edinburgh
27 CUMS - Capital University of Medical Sciences [Beijing]
28 HUEP - Hôpitaux Universitaires de l'Est Parisien [Paris]
29 Monash Medical Centre [Clayton, Australia]
30 CUTN - Central University of Tamil Nadu [Thiruvarur, India]
31 OTRH - Okmeydani Training and Research Hospital [Istanbul, Turkey]
32 CICD - Centre International de Cancérologie de Dakar [Dakar, Senegal]
33 Aristotle University of Thessaloniki
34 University Hospital Southampton NHS Foundation Trust
35 UVS - Université Virtuelle du Sénégal [Dakar, Senegal]
36 IThEM - U1140 - Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis
37 UCH - University Clinic of Hematology [Skopje, Republic of North Macedonia]
38 UMP - University of Medicine and Pharmacy [Cluj-Napoca, Romania]
39 Service d'Anesthésie réanimation [CHU Tenon]
40 2FTH - Flor Ferenc Teaching Hospital [Kistarcsa, Hungary]
41 San Camillo Forlanini Hospital [Rome]
42 LUMC - Loyola University Medical Center
43 SVRI - Science Valley Research Institute [São Paulo, Brazil]
44 KH2C - King Hussein Cancer Center [Amman, Jordan]
45 HFB - CHU Fattouma Bourguiba [Monastir]
46 Medizinische Universität Wien = Medical University of Vienna
47 Nobelpharma Co. Ltd. [Tokyo, Japan]
48 ULB - Hôpital Erasme [Bruxelles]
49 NSUC - North Shore University Cardiologists [Skokie, Illinois, USA]
50 AUB - American University of Beirut Faculty of Medicine and Medical Center
51 KEVB - Klinikum Ernst von Bergmann [Potsdam, Germany]
52 Peking University [Beijing]
53 CAMS - Chinese Academy of Medical Sciences [Beijing, China]
54 UM5 - Université Mohammed V de Rabat [Agdal]
2 CHU Tenon [AP-HP]
3 UNIMI - Università degli Studi di Milano = University of Milan
4 CIMI - Centre d'Immunologie et des Maladies Infectieuses
5 Sechenov First Moscow State Medical University
6 CU - Campbell University [Buies Creek, NC, USA]
7 University of Karachi
8 Heidelberg University
9 UNIMIB - Università degli Studi di Milano-Bicocca = University of Milano-Bicocca
10 Loyola University [Chicago]
11 CyI - Cyprus Institute
12 University of Belgrade [Belgrade]
13 NVC - Nuova Villa Claudia [Rome, Italy]
14 UCAM - Universidad Católica San Antonio de Murcia
15 Rambam Health Care Campus [Haifa, Israel]
16 Technion - Israel Institute of Technology [Haifa]
17 MHRF - Ministry of Health of the Russian Federation
18 St James's University Hospital
19 Trinity College Dublin
20 NKUA - National and Kapodistrian University of Athens
21 McMaster University [Hamilton, Ontario]
22 FIRH - Firestone Institute for Respiratory Health [Hamilton, ON, Canada]
23 Ministry of Health [Saudi Arabia]
24 SIH - Szent Imre Hospital [Budapest, Hungary]
25 Mashhad University of Medical Sciences
26 University of Edinburgh
27 CUMS - Capital University of Medical Sciences [Beijing]
28 HUEP - Hôpitaux Universitaires de l'Est Parisien [Paris]
29 Monash Medical Centre [Clayton, Australia]
30 CUTN - Central University of Tamil Nadu [Thiruvarur, India]
31 OTRH - Okmeydani Training and Research Hospital [Istanbul, Turkey]
32 CICD - Centre International de Cancérologie de Dakar [Dakar, Senegal]
33 Aristotle University of Thessaloniki
34 University Hospital Southampton NHS Foundation Trust
35 UVS - Université Virtuelle du Sénégal [Dakar, Senegal]
36 IThEM - U1140 - Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis
37 UCH - University Clinic of Hematology [Skopje, Republic of North Macedonia]
38 UMP - University of Medicine and Pharmacy [Cluj-Napoca, Romania]
39 Service d'Anesthésie réanimation [CHU Tenon]
40 2FTH - Flor Ferenc Teaching Hospital [Kistarcsa, Hungary]
41 San Camillo Forlanini Hospital [Rome]
42 LUMC - Loyola University Medical Center
43 SVRI - Science Valley Research Institute [São Paulo, Brazil]
44 KH2C - King Hussein Cancer Center [Amman, Jordan]
45 HFB - CHU Fattouma Bourguiba [Monastir]
46 Medizinische Universität Wien = Medical University of Vienna
47 Nobelpharma Co. Ltd. [Tokyo, Japan]
48 ULB - Hôpital Erasme [Bruxelles]
49 NSUC - North Shore University Cardiologists [Skokie, Illinois, USA]
50 AUB - American University of Beirut Faculty of Medicine and Medical Center
51 KEVB - Klinikum Ernst von Bergmann [Potsdam, Germany]
52 Peking University [Beijing]
53 CAMS - Chinese Academy of Medical Sciences [Beijing, China]
54 UM5 - Université Mohammed V de Rabat [Agdal]
Grigoris Gerotziafas
- Function : Author
- PersonId : 765963
- IdHAL : grigoris-gerotziafas
- ORCID : 0000-0003-2316-6348
Ismail Elalamy
- Function : Author
- PersonId : 760610
- ORCID : 0000-0003-3465-2499
Anna Falanga
- Function : Author
- PersonId : 777016
- ORCID : 0000-0002-5007-3457
Jawed Fareed
- Function : Author
- PersonId : 760610
- ORCID : 0000-0003-3465-2499
Joseph Lewis
- Function : Author
- PersonId : 791016
- ORCID : 0000-0001-7917-8474
Michèle Sabbah
- Function : Author
- PersonId : 767094
- IdHAL : michele-sabbah
- ORCID : 0000-0001-5368-9022
- IdRef : 110954947
Anny Slama-Schwok
- Function : Author
- PersonId : 801089
- ORCID : 0000-0002-2703-9728
Abstract
Background One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and devastating public health crisis. Management Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success of these NPIs is dependent on the approval and commitment of the population. The launch of a mass vaccination program in many countries in late December 2020 with mRNA vaccines, adenovirus-based vaccines, and inactivated virus vaccines has generated hope for the end of the pandemic. Current Issues The continuous appearance of new pathogenic viral strains and the ability of vaccines to prevent infection and transmission raise important concerns as we try to achieve community immunity against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variants. The need of a second and even third generation of vaccines has already been acknowledged by the WHO and governments. Perspectives There is a critical and urgent need for a balanced and integrated strategy for the management of the COVID-19 outbreaks organized on three axes: (1) Prevention of the SARS-CoV-2 infection, (2) Detection and early diagnosis of patients at risk of disease worsening, and (3) Anticipation of medical care (PDA). Conclusion The “PDA strategy” integrated into state policy for the support and expansion of health systems and introduction of digital organizations (i.e., telemedicine, e-Health, artificial intelligence, and machine-learning technology) is of major importance for the preservation of citizens' health and life world-wide.
Domains
Biochemistry, Molecular Biology
Origin : Publication funded by an institution