Abstract : Environmental enrichment (EE) has been shown to produce powerful beneficial effects in animal models of addiction. In particular, the ability of EE to promote abstinence and prevent relapse may allow for the identification of brain mechanisms responsible for the recovery from addiction. Indeed, the effects of EE on specific brain mechanisms could be mimicked by old or new molecules, which may become novel medications, called enviromimetics. Here, we review the best known enviromimetics for the treatment of addiction and suggest that, whereas these compounds may be relatively ineffective by themselves, they may be useful complements for existing therapeutic approaches to manage addiction which includes behavioural, environmental and pharmacological interventions.
https://www.hal.inserm.fr/inserm-03379540 Contributor : Marcello SOLINASConnect in order to contact the contributor Submitted on : Friday, October 15, 2021 - 8:45:17 AM Last modification on : Sunday, June 26, 2022 - 3:16:01 AM Long-term archiving on: : Sunday, January 16, 2022 - 6:18:26 PM
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