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Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4)

Abstract : The French Hospital Database on HIV (FHDH) is a hospital-based multicentre open cohort with inclusions ongoing since 1989. The research objectives focus mainly on mid- and long-term clinical outcomes and therapeutic strategies, as well as severe AIDS and non-AIDS morbidities, and public health issues relative to HIV infection. FHDH also serves to describe HIV-infected patients receiving hospital care in France. FHDH includes data on more than 120,000 HIV-infected patients from 70 French general or university hospitals distributed throughout France. Patients are eligible for inclusion if they are infected by HIV-1 or HIV-2 and give their written informed consent. Standardized variables are collected at each outpatient visit or hospital admission during which a new clinical manifestation is diagnosed, a new treatment is prescribed or a change in biological markers is noted, and/or at least every 6 months. Since its inception, variables collected in FHDH include demographic characteristics, HIV-related biological markers, the date and type of AIDS and non AIDS-defining events, antiretroviral treatments and the date and causes of death, as reported in the medical records. Since 2005, data have also been collected on: co-infection with hepatitis B or C virus; alcohol and tobacco use; and non HIV-related biomarkers. Anyone can submit a research project by completing a standardized form available on the FHDH website ( or from the corresponding author, describing the context and objectives of the study. All projects are reviewed by the scientific committee.
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Submitted on : Monday, September 27, 2021 - 11:33:32 AM
Last modification on : Thursday, April 7, 2022 - 10:10:46 AM

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Murielle Mary-Krause, Sophie Grabar, L Lievre, Sophie Abgrall, Eric Billaud, et al.. Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4). International Journal of Epidemiology, Oxford University Press (OUP), 2014, 43 (5), pp.1425 - 1436. ⟨10.1093/ije/dyu002⟩. ⟨inserm-03355232⟩



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