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Recommandations pour la mise en place d’études multicentriques avec IRM

Abstract : MRI is becoming increasingly important in clinical research studies, both in terms of inclusion criteria and endpoints. Markers based on MRI acquisitions are now regularly considered as primary endpoints. Especially in multicentre studies, the management of MRI acquisitions has to take into account the heterogeneity of MRI systems in terms of manufacturers, magnetic fields, coils and software versions. This is due to the number of important parameters that can be specified and optimised to obtain MR images, the variability between the solutions proposed by the manufacturers and the regular technical innovations. The aim of this article is to detail the steps and the people to involve in order to carry out an MRI study. Based on the experience and expertise of the members of the Réseau d’entraide multicentrique en IRM (REMI), we propose detailed recommendations to the French-speaking community, in order to better take into account the specificities of MRI at all stages of the study and to participate in improving the quality of MRI research. These recommendations also take into account the specificities of MRI research platforms and clinical imaging services, as well as regulatory constraints.
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Submitted on : Thursday, July 22, 2021 - 2:42:35 PM
Last modification on : Friday, May 20, 2022 - 11:06:47 AM
Long-term archiving on: : Saturday, October 23, 2021 - 6:37:47 PM


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Gabriela Hossu, Irène Troprès, Emmanuelle Le Bars, Jean-Luc Anton, Marie Chupin, et al.. Recommandations pour la mise en place d’études multicentriques avec IRM. Journal d'imagerie diagnostique et interventionnelle, Elsevier, 2021, pp.1-11. ⟨10.1016/j.jidi.2021.04.003⟩. ⟨inserm-03275595⟩



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