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No evidence of SARS-CoV-2 transfusion transmission despite RNA detection in blood donors showing symptoms after donation

Pierre Cappy 1 Daniel Candotti 1 Virginie Sauvage 1 Quentin Lucas 1 Laure Boizeau 1 Johanna Gomez 1 Vincent Enouf 2, 3 Lila Chabli 4 Josiane Pillonel 5 Pierre Tiberghien 4, 6 Pascal Morel 4, 6 Syria Laperche 1
1 INTS - Institut National de la Transfusion Sanguine [Paris]
2 GMV-ARN (UMR_3569 / U-Pasteur_2) - Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses
3 CNR - Centre National de Référence des virus des infections respiratoires (dont la grippe) - National Reference Center Virus Influenzae [Paris]
4 EFS - Etablissement Français du Sang [La Plaine Saint-Denis]
5 Direction des maladies infectieuses - Infectious Diseases Division [Saint-Maurice]
6 RIGHT - Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098)
Abstract : The diagnosis of chronic mountain sickness (CMS) is based on a score including 7 clinical features (breathlessness, sleep disturbance, cyanosis, venous dilatation, paresthesia, headache, and tinnitus) in the setting of extreme erythrocytosis. Examining individuals in La Rinconada, Peru, the highest city in the world, the authors demonstrated that CMS at extreme altitude is not linked to elevation of hemoglobin, since CMS+ and CMS− individuals had similar levels of erythrocytosis.
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https://www.hal.inserm.fr/inserm-03237676
Contributor : Daniel Candotti Connect in order to contact the contributor
Submitted on : Wednesday, May 26, 2021 - 5:38:45 PM
Last modification on : Friday, January 14, 2022 - 3:08:27 AM
Long-term archiving on: : Friday, August 27, 2021 - 8:41:50 PM

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INSERM | PASTEUR | UNIV-FCOMTE | CNRS | UP-SCIENCES | UNIV-PARIS

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Pierre Cappy, Daniel Candotti, Virginie Sauvage, Quentin Lucas, Laure Boizeau, et al.. No evidence of SARS-CoV-2 transfusion transmission despite RNA detection in blood donors showing symptoms after donation. Blood, American Society of Hematology, 2020, 136 (16), pp.1888-1891. ⟨10.1182/blood.2020008230⟩. ⟨inserm-03237676⟩

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