Of mice and men: fuzzy tandem repeats and divergent p53 transcriptional repertoires - Archive ouverte HAL Access content directly
Journal Articles Transcription Year : 2014

Of mice and men: fuzzy tandem repeats and divergent p53 transcriptional repertoires

(1) , (1) , (1) , (1) , (1) , (1)
1
Aurélie Morin
Franck Toledo
  • Function : Author
  • PersonId : 980869

Abstract

The clinical importance of tumor suppressor p53 makes it one of the most studied transcription factors. A comparison of mammalian p53 transcriptional repertoires may help identify fundamental principles in genome evolution and better understand cancer processes. Here we summarize mechanisms underlying the divergence of mammalian p53 transcriptional repertoires, with an emphasis on the rapid evolution of fuzzy tandem repeats containing p53 response elements.

Dates and versions

inserm-03198945 , version 1 (15-04-2021)

Identifiers

Cite

Aurélie Morin, Boris Bardot, Iva Simeonova, Vincent Lejour, Rachida Bouarich-Bourimi, et al.. Of mice and men: fuzzy tandem repeats and divergent p53 transcriptional repertoires. Transcription, 2014, 4 (2), pp.67-71. ⟨10.4161/trns.23772⟩. ⟨inserm-03198945⟩
12 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More