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Journal Articles European Journal of Immunology Year : 2020

Blood microparticles are a component of immune modulation in red blood cell transfusion

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Abstract

Patients may display alloimmunization following transfusion. Microparticles (MPs) released into the blood are present in transfusion products. We show that MPs can modulate the immune system, CD4+ T-cell, and humoral responses, through their concentration, cellular origin and phenotype, and should therefore be considered to reduce the immune impact of transfusion.
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Dates and versions

inserm-03129769 , version 1 (03-02-2021)

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Marion Klea Pinheiro, Marie Tamagne, Rahma Elayeb, Muriel Andrieu, France Pirenne, et al.. Blood microparticles are a component of immune modulation in red blood cell transfusion. European Journal of Immunology, 2020, 50, pp.1237 - 1240. ⟨10.1002/eji.201948481⟩. ⟨inserm-03129769⟩
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