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Blood microparticles are a component of immune modulation in red blood cell transfusion

Abstract : Patients may display alloimmunization following transfusion. Microparticles (MPs) released into the blood are present in transfusion products. We show that MPs can modulate the immune system, CD4+ T-cell, and humoral responses, through their concentration, cellular origin and phenotype, and should therefore be considered to reduce the immune impact of transfusion.
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https://www.hal.inserm.fr/inserm-03129769
Contributor : Benoit Vingert <>
Submitted on : Wednesday, February 3, 2021 - 9:38:29 AM
Last modification on : Wednesday, June 2, 2021 - 4:26:10 PM
Long-term archiving on: : Tuesday, May 4, 2021 - 6:22:00 PM

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Marion Pinheiro, Marie Tamagne, Rahma Elayeb, Muriel Andrieu, France Pirenne, et al.. Blood microparticles are a component of immune modulation in red blood cell transfusion. European Journal of Immunology, Wiley-VCH Verlag, 2020, 50, pp.1237 - 1240. ⟨10.1002/eji.201948481⟩. ⟨inserm-03129769⟩

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