Abstract : Safe and effective treatment with direct-acting antivirals (DAAs) has ushered in an era in which hepatitis C virus (HCV) elimination, as set out by the World Health Organization, is possible. However, alcohol use disorder (AUD) has the potential to reduce the benefits of prevention interventions and reduce access to and continuity of HCV care in at-risk populations, such as people who inject drugs (PWID). We review the literature on the consequences of AUD on the effectiveness of HCV prevention and the cascade of care in PWID and provide recommendations for future research in the field of alcohol use and HCV.
https://www.hal.inserm.fr/inserm-03121677
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Fabienne Marcellin, Antoine Jaquet, Jeffrey Lazarus, Patricia Molina, Patrizia Carrieri. Alcohol Use Disorder and Hepatitis C Prevention and Care in People Who Inject Drugs: The State of Play. Seminars in Liver Disease, Thieme Publishing, 2020, Online ahead of print. ⟨10.1055/s-0040-1716343⟩. ⟨inserm-03121677⟩