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Arthrose : des traitements à venir aux traitements d’avenir

Abstract : Osteoarthritis affects hundreds of millions of people worldwide, and its prevalence is constantly increasing. While there is no effective treatment to date, new promising therapeutic strategies and targets are being investigated. Innovative cell therapies are reaching clinical trials, and the most recent progress in our understanding of the pathology is opening new routes for gene therapy. In the long term, the development of new biofabrication tools such as 3D bioprinting might pave the way for the use of personalized mini-joint models that would allow clinicians to screen drugs and personalize treatments. This review offers an overview of the most promising therapeutic approaches in the field of osteoarthritis, from coming treatments to those that are yet to be discovered.
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https://www.hal.inserm.fr/inserm-03109864
Contributor : Valérie Pecqueret <>
Submitted on : Thursday, January 14, 2021 - 9:42:53 AM
Last modification on : Tuesday, February 16, 2021 - 11:56:56 AM

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Vianney Delplace, Marie-Astrid Boutet, Catherine Le Visage, Yves Maugars, Jérôme Guicheux, et al.. Arthrose : des traitements à venir aux traitements d’avenir. Revue du Rhumatisme monographies, Elsevier, 2020, Online ahead of print. ⟨10.1016/j.monrhu.2020.12.004⟩. ⟨inserm-03109864⟩

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