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Dysregulated lipid metabolism links NAFLD to cardiovascular disease

Abstract : Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming a global health problem. Cardiovascular diseases (CVD) are the most common cause of mortality in NAFLD patients. NAFLD and CVD share several common risk factors including obesity, insulin resistance, and type 2 diabetes (T2D). Atherogenic dyslipidemia, characterized by plasma hypertriglyceridemia, increased small dense low-density lipoprotein (LDL) particles, and decreased high-density lipoprotein cholesterol (HDL-C) levels, is often observed in NAFLD patients.
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Submitted on : Thursday, November 19, 2020 - 2:13:23 PM
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Audrey Deprince, Joel Haas, Bart Staels. Dysregulated lipid metabolism links NAFLD to cardiovascular disease. Molecular metabolism, Elsevier, 2020, 42, pp.101092. ⟨10.1016/j.molmet.2020.101092⟩. ⟨inserm-03014459⟩



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