Varon Administrative, technical, or material support (i.e., reporting or organizing data, constructing databases): L. Chambonnier, N. Senant-Dugot Study supervision: S. Evrard, F. M egraud, C. Varon References 1. World Health Organization, International Agency for Research on Cancer. Schistosomes, liver flukes, and Helicobacter pylori, No potential conflicts of interest were disclosed by the other authors. Authors' Contributions Conception, vol.61, pp.177-240 ,
Helicobacter pylori infection and gastric carcinoma, Clinical Microbiology and Infection, vol.21, issue.11, pp.984-990, 2015. ,
THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA, Acta Pathologica Microbiologica Scandinavica, vol.64, issue.1, pp.31-49, 1965. ,
D ,
URL : https://hal.archives-ouvertes.fr/halshs-01484157
Perioral Dermatitis Successfully Treated with Topical Ivermectin, Annals of Dermatology, vol.31, issue.Suppl, p.S27, 2019. ,
Personalizing therapies for gastric cancer: Molecular mechanisms and novel targeted therapies, World Journal of Gastroenterology, vol.19, issue.38, p.6383, 2013. ,
Comprehensive molecular characterization of gastric adenocarcinoma, Nature, vol.513, issue.7517, pp.202-209, 2014. ,
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer, Nature Genetics, vol.46, issue.6, pp.573-582, 2014. ,
The cancer stem cell: premises, promises and challenges, Nature Medicine, vol.17, issue.3, pp.313-319, 2011. ,
Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer, Cell Stem Cell, vol.17, issue.3, pp.260-271, 2015. ,
Biological and clinical significance of cancer stem cell plasticity, Clinical and Translational Medicine, vol.3, issue.1, p.32, 2014. ,
Prospective identification of tumorigenic breast cancer cells, Proceedings of the National Academy of Sciences, vol.100, issue.7, pp.3983-3988, 2003. ,
Identification of Pancreatic Cancer Stem Cells, Cancer Research, vol.67, issue.3, pp.1030-1037, 2007. ,
Prospective Identification of Tumorigenic Prostate Cancer Stem Cells, Cancer Research, vol.65, issue.23, pp.10946-10951, 2005. ,
Identification of human brain tumour initiating cells, Nature, vol.432, issue.7015, pp.396-401, 2004. ,
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice, Nature, vol.445, issue.7123, pp.106-110, 2006. ,
Identification and expansion of human colon-cancer-initiating cells, Nature, vol.445, issue.7123, pp.111-115, 2006. ,
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome, Cell Stem Cell, vol.1, issue.5, pp.555-567, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-01431968
Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer, Molecular Cancer Research, vol.7, issue.3, pp.330-338, 2009. ,
Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis, Cancer Research, vol.69, issue.8, pp.3382-3389, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-01431953
The Role of Human Aldehyde Dehydrogenase in Normal and Cancer Stem Cells, Stem Cell Reviews and Reports, vol.7, issue.2, pp.292-306, 2010. ,
Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44, Stem Cells, vol.27, issue.5, pp.1006-1020, 2009. ,
CD133 and CD44 Cell surface markers do not identify cancer stem cells in primary human gastric tumors, Journal of Cellular Physiology, vol.227, issue.6, pp.2686-2693, 2012. ,
Gastric Cancer Originating from Bone Marrow-Derived Cells, Science, vol.306, issue.5701, pp.1568-1571, 2004. ,
Helicobacter pylori Infection Recruits Bone Marrow?Derived Cells That Participate in Gastric Preneoplasia in Mice, Gastroenterology, vol.142, issue.2, pp.281-291, 2012. ,
Helicobacter pylori infection and stem cells at the origin of gastric cancer, Oncogene, vol.34, issue.20, pp.2547-2555, 2014. ,
Helicobacter pylori generates cells with cancer stem cell properties via epithelial?mesenchymal transition-like changes, Oncogene, vol.33, issue.32, pp.4123-4131, 2013. ,
Human Bone Marrow-Derived Stem Cells Acquire Epithelial Characteristics through Fusion with Gastrointestinal Epithelial Cells, PLoS ONE, vol.6, issue.5, p.e19569, 2011. ,
Tumor initiating potential of side population cells in human gastric cancer, Int J Oncol, vol.34, pp.1201-1208, 2009. ,
The CD10 Enzyme Is a Key Player to Identify and Regulate Human Mammary Stem Cells, STEM CELLS, vol.28, issue.6, pp.1081-1088, 2010. ,
Phenotypic characterization of human colorectal cancer stem cells, Proceedings of the National Academy of Sciences, vol.104, issue.24, pp.10158-10163, 2007. ,
Generation of a functional mammary gland from a single stem cell, Nature, vol.439, issue.7072, pp.84-88, 2006. ,
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement, Cytotherapy, vol.8, issue.4, pp.315-317, 2006. ,
The Hyaluronic Acid Receptor CD44 Coordinates Normal and Metaplastic Gastric Epithelial Progenitor Cell Proliferation, Journal of Biological Chemistry, vol.288, issue.22, pp.16085-16097, 2013. ,
Expression of CD44 containing variant exon 9 (CD44v9) in gastric adenomas and adenocarcinomas: relation to the proliferation and progression., International Journal of Oncology, vol.12, pp.1253-1261, 1998. ,
Expression of heparanase gene, CD44v6, MMP-7 andnm23protein and their relationship with the invasion and metastasis of gastric carcinomas, World Journal of Gastroenterology, vol.10, issue.6, p.776, 2004. ,
De novo expression of CD44 variants in sporadic and hereditary gastric cancer, Laboratory Investigation, vol.90, issue.11, pp.1604-1614, 2010. ,
CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells, Cancer Research, vol.74, issue.9, pp.2630-2641, 2014. ,
CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation, PLOS Pathogens, vol.11, issue.2, p.e1004663, 2015. ,
Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts, Stem Cell Reports, vol.2, issue.1, pp.78-91, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01431931
Aldehyde dehydrogenase: Its role as a cancer stem cell marker comes down to the specific isoform, Cell Cycle, vol.10, issue.9, pp.1378-1384, 2011. ,
Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer, Blood, vol.87, issue.3, pp.1097-1103, 1996. ,
Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study, Cancer Chemotherapy and Pharmacology, vol.49, issue.4, pp.309-321, 2002. ,
The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation, Cancer Research, vol.74, issue.13, pp.3579-3590, 2014. ,
Multiple drug resistance due to resistance to stem cells and stem cell treatment progress in cancer (Review), Experimental and Therapeutic Medicine, vol.9, issue.2, pp.289-293, 2014. ,