Beiträge zur Kenntniss der Sassaparille;, Archiv der Pharmazie, vol.102, issue.1, pp.25-64, 1847. ,
Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors, Biomolecules, vol.10, issue.9, p.1240, 2020. ,
URL : https://hal.archives-ouvertes.fr/inserm-03004043
The permeability of red blood corpuscles to organic anions, Journal of Cellular and Comparative Physiology, vol.7, issue.3, pp.367-391, 1936. ,
The electrical constants of Purkinje fibres, The Journal of Physiology, vol.118, issue.3, pp.348-360, 1952. ,
Intercellular Diffusion, Science, vol.143, issue.3609, pp.959-960, 1964. ,
Intercellular Communication and the Control of Tissue Growth: Lack of Communication between Cancer Cells, Nature, vol.209, issue.5029, pp.1248-1249, 1966. ,
HEXAGONAL ARRAY OF SUBUNITS IN INTERCELLULAR JUNCTIONS OF THE MOUSE HEART AND LIVER, Journal of Cell Biology, vol.33, issue.3, pp.C7-12, 1967. ,
Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature., Journal of Cell Biology, vol.67, issue.3, pp.863-885, 1975. ,
Gap junction structures: Analysis of the x-ray diffraction data, Journal of Cell Biology, vol.74, issue.2, pp.629-645, 1977. ,
Communication of cAMP by connexin43 gap junctions regulates osteoblast signaling and gene expression, Cellular Signalling, vol.28, issue.8, pp.1048-1057, 2016. ,
Transfer of Biologically Important Molecules Between Cells Through Gap Junction Channels, Current Medicinal Chemistry, vol.10, issue.19, pp.2045-2058, 2003. ,
Therapeutic strategies targeting connexins, Nature Reviews Drug Discovery, vol.17, issue.12, pp.905-921, 2018. ,
Gap junctions and cancer: communicating for 50 years, Nature Reviews Cancer, vol.16, issue.12, pp.775-788, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01437427
Connexin-26 Is a Key Factor Mediating Gemcitabine Bystander Effect, Molecular Cancer Therapeutics, vol.10, issue.3, pp.505-517, 2011. ,
Formation of the gap junction intercellular channel requires a 30° rotation for interdigitating two apposing connexons, Journal of Molecular Biology, vol.277, issue.2, pp.171-177, 1998. ,
Three-Dimensional Structure of a Recombinant Gap Junction Membrane Channel, Science, vol.283, issue.5405, pp.1176-1180, 1999. ,
Gap-junction-mediated cell-to-cell communication, Cell and Tissue Research, vol.352, issue.1, pp.21-31, 2012. ,
Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer, Frontiers in Medicine, vol.6, 2019. ,
Connexins and microRNAs: Interlinked players in regulating islet function?, Islets, vol.9, issue.5, pp.99-108, 2017. ,
Gap junctions modulate glioma invasion by direct transfer of microRNA, Oncotarget, vol.6, issue.17, pp.15566-15577, 2015. ,
Pattern of cell?to?cell transfer of micro RNA by gap junction and its effect on the proliferation of glioma cells, Cancer Science, vol.110, issue.6, pp.1947-1958, 2019. ,
Plasma membrane channels formed by connexins: Their regulation and functions, Physiol. Rev, vol.83, pp.1359-1400, 2003. ,
Connexin-based gap junction hemichannels: Gating mechanisms, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1711, issue.2, pp.215-224, 2005. ,
Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins, Journal of Cell Science, vol.120, issue.21, pp.3772-3783, 2007. ,
Pannexin 1 channels mediate ?find-me? signal release and membrane permeability during apoptosis, Nature, vol.467, issue.7317, pp.863-867, 2010. ,
Possible role of hemichannels in cancer, Frontiers in Physiology, vol.5, 2014. ,
Gap junctions and the connexin protein family, Cardiovasc. Res, vol.62, pp.228-232, 2004. ,
Protective effect of genetic deletion of pannexin1 in experimental mouse models of acute and chronic liver disease, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1864, issue.3, pp.819-830, 2018. ,
An Update on Connexin Genes and their Nomenclature in Mouse and Man, Cell Communication & Adhesion, vol.10, issue.4-6, pp.173-180, 2003. ,
Connexins: Key Mediators of Endocrine Function, Physiological Reviews, vol.91, issue.4, pp.1393-1445, 2011. ,
Topological analysis of the major protein in isolated intact rat liver gap junctions and gap junction-derived single membrane structures, J. Biol. Chem, vol.262, pp.7751-7763, 1987. ,
Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes, Biochemical Journal, vol.273, issue.1, pp.67-72, 1991. ,
The N-Terminal Half of the Connexin Protein Contains the Core Elements of the Pore and Voltage Gates, The Journal of Membrane Biology, vol.245, issue.8, pp.453-463, 2012. ,
Structure and closure of connexin gap junction channels, FEBS Letters, vol.588, issue.8, pp.1230-1237, 2014. ,
Gap Junctions: Basic Structure and Function, Journal of Investigative Dermatology, vol.127, issue.11, pp.2516-2524, 2007. ,
Connexin gene mutations in human genetic diseases, Mutation Research/Reviews in Mutation Research, vol.462, issue.2-3, pp.197-207, 2000. ,
Posttranslational Modifications in Connexins and Pannexins, The Journal of Membrane Biology, vol.245, issue.5-6, pp.319-332, 2012. ,
Acetylation of C-terminal lysines modulates protein turnover and stability of Connexin-32, BMC Cell Biology, vol.19, issue.1, 2018. ,
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43, Journal of Biological Chemistry, vol.293, issue.21, pp.8275-8284, 2018. ,
Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications, Cellular and Molecular Life Sciences, vol.77, issue.4, pp.573-591, 2019. ,
Regulation of gap junction channels and hemichannels by phosphorylation and redox changes: a revision, BMC Cell Biology, vol.17, issue.S1, 2016. ,
Modulation of gap junction channels and hemichannels by growth factors, Molecular BioSystems, vol.8, issue.3, p.685, 2012. ,
Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease, International Journal of Molecular Sciences, vol.19, issue.5, p.1296, 2018. ,
High Glucose Down-regulates Intercellular Communication in Retinal Endothelial Cells by Enhancing Degradation of Connexin 43 by a Proteasome-dependent Mechanism, Journal of Biological Chemistry, vol.279, issue.26, pp.27219-27224, 2004. ,
Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1711, issue.2, pp.172-182, 2005. ,
INTERCELLULAR COMMUNICATION AND TISSUE GROWTH, Journal of Cell Biology, vol.33, issue.2, pp.225-234, 1967. ,
Cancer Connectors: Connexins, Gap Junctions, and Communication, Frontiers in Oncology, vol.8, p.646, 2018. ,
Facets of Communication: Gap Junction Ultrastructure and Function in Cancer Stem Cells and Tumor Cells, Cancers, vol.11, issue.3, p.288, 2019. ,
Connexin 43 (Cx43) in cancer: Implications for therapeutic approaches via gap junctions, Cancer Letters, vol.442, pp.439-444, 2019. ,
Gap Junction Intercellular Communication in the Carcinogenesis Hallmarks: Is This a Phenomenon or Epiphenomenon?, Cells, vol.8, issue.8, p.896, 2019. ,
Connexins and Gap Junctions in Cancer of the Urinary Tract, Cancers, vol.11, issue.5, p.704, 2019. ,
Connexins in cancer: bridging the gap to the clinic, Oncogene, vol.38, issue.23, pp.4429-4451, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02129342
Reduced cell-cell communication between mitotic and nonmitotic coupled cells, Experimental Cell Research, vol.198, issue.1, pp.1-7, 1992. ,
Connexins and their channels in cell growth and cell death, Cellular Signalling, vol.18, issue.5, pp.592-600, 2006. ,
Connexins: junctional and non-junctional modulators of proliferation, Cell and Tissue Research, vol.360, issue.3, pp.685-699, 2014. ,
Deficiency of connexin43 gap junctions is an independent marker for breast tumors, Cancer Res, vol.59, pp.4104-4110, 1999. ,
Connexin?s Connection in Breast Cancer Growth and Progression, International Journal of Cell Biology, vol.2016, pp.1-11, 2016. ,
Aberrant Cx43 Expression and Mislocalization in Metastatic Human Melanomas, Journal of Cancer, vol.8, issue.7, pp.1123-1128, 2017. ,
Expression and significance of Cx43 and E-cadherin in gastric cancer and metastatic lymph nodes, Medical Oncology, vol.28, issue.2, pp.502-508, 2010. ,
Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients, Archives of Medical Science, vol.16, issue.2, pp.352-358, 2020. ,
Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters, Medical Oncology, vol.27, issue.4, pp.1164-1170, 2009. ,
Inhibition of miR30a-3p by sulforaphane enhances gap junction intercellular communication in pancreatic cancer, Cancer Letters, vol.469, pp.238-245, 2020. ,
Expression of connexin 43 in breast cancer in comparison with mammary dysplasia and the normal mammary gland, Folia Morphol, vol.62, pp.439-442, 2003. ,
Cx43 Expression Correlates with Breast Cancer Metastasis in MDA-MB-231 Cells In Vitro, In a Mouse Xenograft Model and in Human Breast Cancer Tissues, Cancers, vol.11, issue.4, p.460, 2019. ,
Gap Junctions and Breast Cancer Dormancy, Trends in Cancer, vol.6, issue.4, pp.348-357, 2020. ,
Increased susceptibility to urethane-induced lung tumors in mice with decreased expression of connexin43, Carcinogenesis, vol.25, issue.10, pp.1973-1982, 2004. ,
Connexin43 Reduces Melanoma Growth within a Keratinocyte Microenvironment and during Tumorigenesisin Vivo, Journal of Biological Chemistry, vol.289, issue.3, pp.1592-1603, 2013. ,
Overexpression of connexin 43 reduces melanoma proliferative and metastatic capacity, British Journal of Cancer, vol.113, issue.2, pp.259-267, 2015. ,
Connexins and Pannexins: Important Players in Tumorigenesis, Metastasis and Potential Therapeutics, International Journal of Molecular Sciences, vol.19, issue.6, p.1645, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02129346
Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter, Science, vol.206, issue.4422, pp.1089-1091, 1979. ,
Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells, Biochemical and Biophysical Research Communications, vol.91, issue.2, pp.395-401, 1979. ,
Connexin and pannexin channels in cancer, BMC Cell Biology, vol.17, issue.S1, 2016. ,
Gap Junctions Enhance the Antiproliferative Effect of MicroRNA-124-3p in Glioblastoma Cells, Journal of Cellular Physiology, vol.230, issue.10, pp.2476-2488, 2015. ,
Regulation of Connexin-43 Gap Junctional Intercellular Communication by Mitogen-activated Protein Kinase, Journal of Biological Chemistry, vol.273, issue.15, pp.9188-9196, 1998. ,
Epidermal growth factor disrupts gap-junctional communication and induces phosphorylation of connexin43 on serine., Molecular Biology of the Cell, vol.3, issue.8, pp.865-874, 1992. ,
The effects of connexin phosphorylation on gap junctional communication, The International Journal of Biochemistry & Cell Biology, vol.36, issue.7, pp.1171-1186, 2004. ,
Platelet-derived growth factor-induced disruption of gap junctional communication and phosphorylation of connexin43 involves protein kinase C and mitogen-activated protein kinase, J. Cell Physiol, vol.176, pp.332-341, 1998. ,
Tyrosine Phosphorylation of Connexin 43 by v-Src Is Mediated by SH2 and SH3 Domain Interactions, Journal of Biological Chemistry, vol.272, issue.36, pp.22824-22831, 1997. ,
In vivo association of pp60v-src and the gap-junction protein connexin 43 in v-src-transformed fibroblasts, Mol. Carcinog, vol.25, pp.187-195, 1999. ,
Phosphorylation of connexin43 induced by Src: Regulation of gap junctional communication between transformed cells, Experimental Cell Research, vol.313, issue.20, pp.4083-4090, 2007. ,
Dissection of the Molecular Basis of pp60v-src Induced Gating of Connexin 43 Gap Junction Channels, Journal of Cell Biology, vol.144, issue.5, pp.1033-1045, 1999. ,
Gap junctions and connexin-interacting proteins, Cardiovascular Research, vol.62, issue.2, pp.233-245, 2004. ,
The connexin 43 C-terminus: A tail of many tales, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1860, issue.1, pp.48-64, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02129358
Gap junctional channels are parts of multiprotein complexes, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1818, issue.8, pp.1844-1865, 2012. ,
Connexin43 Carboxyl-Terminal Domain Directly Interacts with ?-Catenin, International Journal of Molecular Sciences, vol.19, issue.6, p.1562, 2018. ,
Gap Junctions and Wnt Signaling in the Mammary Gland: a Cross-Talk?, Journal of Mammary Gland Biology and Neoplasia, vol.24, issue.1, pp.17-38, 2018. ,
Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation, Journal of Cell Science, vol.130, issue.3, pp.531-540, 2017. ,
Connexin43 Interacts with NOV, Journal of Biological Chemistry, vol.279, issue.35, pp.36931-36942, 2004. ,
CCN3 (NOV) Interacts with Connexin43 in C6 Glioma Cells, Journal of Biological Chemistry, vol.279, issue.35, pp.36943-36950, 2004. ,
Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes, Oncotarget, vol.7, issue.31, pp.49819-49833, 2016. ,
Epithelial-to-mesenchymal transition, circulating tumor cells and cancer metastasis: Mechanisms and clinical applications, Oncotarget, vol.8, issue.46, pp.81558-81571, 2017. ,
Signaling pathway cooperation in TGF-?-induced epithelial?mesenchymal transition, Current Opinion in Cell Biology, vol.31, pp.56-66, 2014. ,
Transforming Growth Factor-? Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment, Frontiers in Oncology, vol.8, p.133, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-01814333
Gap junction as an intercellular glue: Emerging roles in cancer EMT and metastasis, Cancer Letters, vol.381, issue.1, pp.133-137, 2016. ,
Cx43 reverses the resistance of A549 lung adenocarcinoma cells to cisplatin by inhibiting EMT, Oncology Reports, vol.31, issue.6, pp.2751-2758, 2014. ,
Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer, Carcinogenesis, vol.35, issue.9, pp.1920-1930, 2014. ,
TGF? modulates cell-to-cell communication in early epithelial-to-mesenchymal transition, Diabetologia, vol.55, issue.3, pp.812-824, 2012. ,
Downregulated connexin32 promotes EMT through the Wnt/?-catenin pathway by targeting Snail expression in hepatocellular carcinoma, International Journal of Oncology, vol.50, issue.6, pp.1977-1988, 2017. ,
Crossing the endothelial barrier during metastasis, Nature Reviews Cancer, vol.13, issue.12, pp.858-870, 2013. ,
Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication, The FASEB Journal, vol.15, issue.3, pp.768-774, 2001. ,
Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture, Breast Cancer Research, vol.7, issue.4, pp.522-534, 2005. ,
Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium, BMC Medicine, vol.6, issue.1, 2008. ,
Role of connexins in metastatic breast cancer and melanoma brain colonization, Journal of Cell Science, vol.126, issue.4, pp.904-913, 2013. ,
Mechanobiology of collective cell behaviours, Nature Reviews Molecular Cell Biology, vol.18, issue.12, pp.743-757, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02348644
Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets, Frontiers in Physiology, vol.8, 2017. ,
Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1863, issue.9, pp.2175-2188, 2016. ,
?V?3 Integrin regulates astrocyte reactivity, Journal of Neuroinflammation, vol.14, issue.1, 2017. ,
Connexins in Astrocyte Migration, Frontiers in Pharmacology, vol.10, 2020. ,
Channel-independent influence of connexin 43 on cell migration, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1818, issue.8, pp.1993-2001, 2012. ,
Phosphorylation of Connexin 43 by Cdk5 Modulates Neuronal Migration During Embryonic Brain Development, Molecular Neurobiology, vol.53, issue.5, pp.2969-2982, 2015. ,
Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex, Frontiers in Cellular Neuroscience, vol.11, 2017. ,
A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK, Stem Cell Reports, vol.9, issue.2, pp.451-463, 2017. ,
The Functional Implications of Endothelial Gap Junctions and Cellular Mechanics in Vascular Angiogenesis, Cancers, vol.11, issue.2, p.237, 2019. ,
SRC3 expressed in BMSCs promotes growth and migration of multiple myeloma cells by regulating the expression of Cx43, International Journal of Oncology, vol.51, issue.6, pp.1694-1704, 2017. ,
Connexin Transfection Induces Invasive Properties in HeLa Cells, Experimental Cell Research, vol.243, issue.1, pp.142-149, 1998. ,
Identification of genes that regulate epithelial cell migration using an siRNA screening approach, Nature Cell Biology, vol.10, issue.9, pp.1027-1038, 2008. ,
Silencing of connexin 43 suppresses invasion, migration and lung metastasis of rat hepatocellular carcinoma cells, Cancer Science, vol.103, issue.5, pp.860-867, 2012. ,
Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus, Glia, vol.55, issue.15, pp.1554-1564, 2007. ,
Opposing roles of connexin43 in glioma progression, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1818, issue.8, pp.2058-2067, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00993056
The carboxy-terminal tail of connexin43 gap junction protein is sufficient to mediate cytoskeleton changes in human glioma cells, Journal of Cellular Biochemistry, vol.110, issue.3, pp.589-597, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02430987
Connexin 43 Enhances the Adhesivity and Mediates the Invasion of Malignant Glioma Cells, The Journal of Neuroscience, vol.22, issue.11, pp.4302-4311, 2002. ,
Increased invasive capacity of connexin43-overexpressing malignant glioma cells, Journal of Neurosurgery, vol.99, issue.6, pp.1039-1046, 2003. ,
The role of the gap junction protein connexin43 in B lymphocyte motility and migration, FEBS Letters, vol.588, issue.8, pp.1249-1258, 2014. ,
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles, Annual Review of Cell and Developmental Biology, vol.30, issue.1, pp.255-289, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-02452769
DNA in extracellular vesicles: biological and clinical aspects, Molecular Oncology, 2020. ,
The Biology of Exosomes in Breast Cancer Progression: Dissemination, Immune Evasion and Metastatic Colonization, Cancers, vol.12, issue.8, p.2179, 2020. ,
Microvesicles in Cancer: Small Size, Large Potential, International Journal of Molecular Sciences, vol.21, issue.15, p.5373, 2020. ,
Role of connexin 43 in different forms of intercellular communication ? gap junctions, extracellular vesicles and tunnelling nanotubes, Journal of Cell Science, vol.130, issue.21, pp.3619-3630, 2017. ,
Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells, Scientific Reports, vol.5, issue.1, 2015. ,
Biological Functions of Connexin43 Beyond Intercellular Communication, Trends in Cell Biology, vol.29, issue.10, pp.835-847, 2019. ,
Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin, Journal of Extracellular Vesicles, vol.5, issue.1, p.32538, 2016. ,
Exosomes in cancer development, metastasis, and immunity, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1871, issue.2, pp.455-468, 2019. ,
Recruitment of RNA molecules by connexin RNA-binding motifs: Implication in RNA and DNA transport through microvesicles and exosomes, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1864, issue.4, pp.728-736, 2017. ,
TGF-? Signaling in Bone Remodeling and Osteosarcoma Progression, Journal of Clinical Medicine, vol.5, issue.11, p.96, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-01701177
The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem, Cells, vol.9, issue.4, p.976, 2020. ,
URL : https://hal.archives-ouvertes.fr/hal-02996147
Marrow stromal stem cells, Journal of Cell Science, vol.1988, issue.Supplement 10, pp.63-76, 1988. ,
Identification of the Human Skeletal Stem Cell, Cell, vol.175, issue.1, pp.43-56.e21, 2018. ,
Transcription factors controlling osteoblastogenesis, Archives of Biochemistry and Biophysics, vol.473, issue.2, pp.98-105, 2008. ,
Runx2: Structure, function, and phosphorylation in osteoblast differentiation, International Journal of Biological Macromolecules, vol.78, pp.202-208, 2015. ,
An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice, Journal of Bone and Mineral Research, vol.28, issue.10, pp.2064-2069, 2013. ,
NFAT and Osterix cooperatively regulate bone formation, Nature Medicine, vol.11, issue.8, pp.880-885, 2005. ,
The Regulation of Osteoclastic Development and Function, Ciba Foundation Symposium 136 - Cell and Molecular Biology of Vertebrate Hard Tissues, vol.136, pp.92-107, 2007. ,
RANK pathway in giant cell tumor of bone: pathogenesis and therapeutic aspects, Tumor Biology, vol.36, issue.2, pp.495-501, 2015. ,
Connexin43 and the Intercellular Signaling Network Regulating Skeletal Remodeling, Current Osteoporosis Reports, vol.15, issue.1, pp.24-31, 2017. ,
Connexins in the skeleton, Seminars in Cell & Developmental Biology, vol.50, pp.31-39, 2016. ,
Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone, BMC Cell Biology, vol.17, issue.S1, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-01322569
Gap junctions and hemichannels in signal transmission, function and development of bone, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1818, issue.8, pp.1909-1918, 2012. ,
Connexin43 Deficiency Causes Delayed Ossification, Craniofacial Abnormalities, and Osteoblast Dysfunction, Journal of Cell Biology, vol.151, issue.4, pp.931-944, 2000. ,
Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function, Journal of Bone and Mineral Research, vol.32, issue.8, pp.1727-1738, 2017. ,
Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43, Journal of Cell Science, vol.119, issue.20, pp.4187-4198, 2006. ,
Attenuated Response to In Vivo Mechanical Loading in Mice With Conditional Osteoblast Ablation of the Connexin43 Gene (Gja1), Journal of Bone and Mineral Research, vol.23, issue.6, pp.879-886, 2008. ,
Gap Junctional Communication Modulates Gene Expression in Osteoblastic Cells, Molecular Biology of the Cell, vol.9, issue.8, pp.2249-2258, 1998. ,
Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells, Bone, vol.25, issue.6, pp.661-666, 1999. ,
Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts, Journal of Cellular Physiology, vol.233, issue.2, pp.946-957, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-01670779
Gap Junctions Regulate Extracellular Signal-regulated Kinase Signaling to Affect Gene Transcription, Molecular Biology of the Cell, vol.16, issue.1, pp.64-72, 2005. ,
Bone-Resorbing Osteoclasts Contain Gap-Junctional Connexin-43, Journal of Bone and Mineral Research, vol.15, issue.5, pp.919-926, 2010. ,
Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors, Biomolecules, vol.10, issue.9, p.1240, 2020. ,
URL : https://hal.archives-ouvertes.fr/inserm-03004043
Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners, Calcified Tissue International, vol.95, issue.1, pp.73-82, 2014. ,
High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation, Journal of Biological Chemistry, vol.289, issue.12, pp.8508-8520, 2014. ,
Oculo-dento-digital dysplasia: Lack of genotype?phenotype correlation for GJA1 mutations and usefulness of neuro-imaging, European Journal of Medical Genetics, vol.53, issue.1, pp.19-22, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00628409
A novel mutation inGJA1causing oculodentodigital syndrome and primary lymphoedema in a three generation family, Clinical Genetics, vol.84, issue.4, pp.378-381, 2013. ,
Connexins and Pannexins in Bone and Skeletal Muscle, Current Osteoporosis Reports, vol.15, issue.4, pp.326-334, 2017. ,
New Insights about the Wnt/?-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?, International Journal of Molecular Sciences, vol.20, issue.15, p.3751, 2019. ,
URL : https://hal.archives-ouvertes.fr/inserm-03004122
SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression, Cells, vol.9, issue.3, p.536, 2020. ,
Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?, Cancers, vol.12, issue.3, p.645, 2020. ,
URL : https://hal.archives-ouvertes.fr/inserm-03004096
Connexin43 suppresses proliferation of osteosarcoma U2OS cells through post-transcriptional regulation of p27, Oncogene, vol.20, issue.31, pp.4138-4149, 2001. ,
Antitumor activity of resveratrol against human osteosarcoma cells: a key role of Cx43 and Wnt/?-catenin signaling pathway, Oncotarget, vol.8, issue.67, pp.111419-111432, 2017. ,
Silencing Ubc9 expression suppresses osteosarcoma tumorigenesis and enhances chemosensitivity to HSV-TK/GCV by regulating connexin?43 SUMOylation, International Journal of Oncology, vol.53, pp.1323-1331, 2018. ,
Up-regulation of connexin 43 and gap junctional intercellular communication by Coleusin Factor is associated with growth inhibition in rat osteosarcoma UMR106 cells, Cell Biology International, vol.31, issue.11, pp.1420-1427, 2007. ,
Effect of gap junction-mediated intercellular communication on TGF-? induced epithelial-to-mesenchymal transition, Biochemical and Biophysical Research Communications, vol.508, issue.3, pp.928-933, 2019. ,
Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1832, issue.4, pp.553-564, 2013. ,
Global cancer statistics, 2012, CA: A Cancer Journal for Clinicians, vol.65, issue.2, pp.87-108, 2015. ,
The Diagnosis and Treatment of Prostate Cancer, JAMA, vol.317, issue.24, p.2532, 2017. ,
Genetics and biology of prostate cancer, Genes & Development, vol.32, issue.17-18, pp.1105-1140, 2018. ,
Translational models of prostate cancer bone metastasis, Nature Reviews Urology, vol.15, issue.7, pp.403-421, 2018. ,
Connexins, important players in the dissemination of prostate cancer cells, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1860, issue.1, pp.202-215, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01578098
Prostate Cancer and Bone Metastases: The Underlying Mechanisms, International Journal of Molecular Sciences, vol.20, issue.10, p.2587, 2019. ,
Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer, Cancers, vol.11, issue.9, p.1370, 2019. ,
Suppression of human prostate cancer cell growth by forced expression of connexin genes, Dev. Genet, vol.24, pp.91-110, 1999. ,
Impaired expression and posttranslational processing of connexin43 and downregulation of gap junctional communication in neoplastic human prostate cells, Prostate, vol.38, pp.55-59, 1999. ,
Gap Junctions and Cancer: New Functions for an Old Story, Antioxidants & Redox Signaling, vol.11, issue.2, pp.323-338, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00425220
Changes in gap junctional connexin isoforms during prostate cancer progression, The Prostate, vol.66, issue.1, pp.19-31, 2006. ,
The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells, Clinical & Experimental Metastasis, vol.29, issue.2, pp.111-122, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00993073
DU-145 prostate carcinoma cells that selectively transmigrate narrow obstacles express elevated levels of Cx43, Cellular and Molecular Biology Letters, vol.16, issue.4, pp.625-637, 2011. ,
Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration, Oncotarget, vol.6, issue.13, pp.11640-11651, 2015. ,
Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine, Molecular and Cellular Biochemistry, vol.391, issue.1-2, pp.259-266, 2014. ,
The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol, European Journal of Pharmacology, vol.634, issue.1-3, pp.101-106, 2010. ,
Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?, Mediat. Inflamm, 2015. ,
The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability, Cancer Cell, vol.34, issue.5, pp.823-839.e7, 2018. ,
Inhibitors of connexin and pannexin channels as potential therapeutics, Pharmacology & Therapeutics, vol.180, pp.144-160, 2017. ,
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid, Biochemical and Biophysical Research Communications, vol.134, issue.1, pp.29-36, 1986. ,
Effect of several uncouplers of cell-to-cell communication on gap junction morphology in mammalian heart, The Journal of Membrane Biology, vol.74, issue.3, pp.203-215, 1983. ,
Heptanol-induced decrease in cardiac gap junctional conductance is mediated by a decrease in the fluidity of membranous cholesterol-rich domains, The Journal of Membrane Biology, vol.136, issue.2, pp.135-145, 1993. ,
Mechanism of heptanol-induced uncoupling of cardiac gap junctions: a perforated patch-clamp study, American Journal of Physiology-Cell Physiology, vol.262, issue.6, pp.C1531-C1538, 1992. ,
Effects of the anesthetics heptanol, halothane and isoflurane on gap junction conductance in crayfish septate axons: A calcium- and hydrogen-independent phenomenon potentiated by caffeine and theophylline, and inhibited by 4-aminopyridine, The Journal of Membrane Biology, vol.121, issue.1, pp.67-78, 1991. ,
Effects of General Anesthetics on Intercellular Communications Mediated by Gap Junctions between Astrocytes in Primary Culture, Anesthesiology, vol.78, issue.5, pp.892-901, 1993. ,
Connexin Modulators and Their Potential Targets under the Magnifying Glass, Current Medicinal Chemistry, vol.17, issue.34, pp.4191-4230, 2010. ,
Therapeutic Targeting of Connexin Channels: New Views and Challenges, Trends in Molecular Medicine, vol.24, issue.12, pp.1036-1053, 2018. ,
Role of Heterocellular Gap Junctional Communication in Endothelium-Dependent Smooth Muscle Hyperpolarization: Inhibition by a Connexin-Mimetic Peptide, Biochemical and Biophysical Research Communications, vol.254, issue.1, pp.27-31, 1999. ,
Peptides Homologous to Extracellular Loop Motifs of Connexin 43 Reversibly Abolish Rhythmic Contractile Activity in Rabbit Arteries, The Journal of Physiology, vol.503, issue.1, pp.99-110, 1997. ,
Connexin43 Mimetic Peptides Reduce Swelling, Astrogliosis, and Neuronal Cell Death after Spinal Cord Injury, Cell Communication & Adhesion, vol.15, issue.1-2, pp.27-42, 2008. ,
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury, Basic Research in Cardiology, vol.108, issue.1, 2012. ,
Functional Block Of Gap Junctional Communication Using Antipeptide Antibodies: Molecular Localisation Of The Putative Binding Sites, Intercellular Communication through Gap Junctions, vol.108, pp.427-430, 1995. ,