Genetics of leprosy: today and beyond, Hum Genet, p.31713021, 2019. ,
Genomewide association study of leprosy, N Engl J Med, vol.361, issue.27, pp.2609-2627, 2009. ,
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy, Nat Genet, vol.47, issue.3, pp.267-71, 2015. ,
A large-scale genome-wide association and metaanalysis identified four novel susceptibility loci for leprosy, Nat Commun, vol.7, p.5172377, 2016. ,
Leprosy and the adaptation of human toll-like receptor 1, PLoS Pathog, vol.6, 2010. ,
Genome-Wide Analysis of Protein-Coding Variants in Leprosy, J Invest Dermatol, vol.137, issue.12, pp.2544-51, 2017. ,
Family-based genomewide association study of leprosy in Vietnam, PLoS Pathog, vol.16, issue.5, 2020. ,
URL : https://hal.archives-ouvertes.fr/inserm-02912259
Major histocompatibility complex genomics and human disease, Annu Rev Genomics Hum Genet, vol.14, p.4426292, 2013. ,
Role of HLA, KIR, MICA, and cytokines genes in leprosy, Biomed Res Int, p.3722889, 2013. ,
Meta-Analysis Identifies Major Histocompatiblity Complex Loci in or Near HLA-DRB1, HLA-DQA1, HLA-C as Associated with Leprosy in Chinese Han Population, J Invest Dermatol, vol.139, issue.4, pp.957-60, 2019. ,
Stepwise replication identifies a lowproducing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy, Nat Genet, vol.39, issue.4, pp.517-539, 2007. ,
Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India, J Infect Dis, vol.203, issue.9, p.3069725, 2011. ,
A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy, PLoS Genet, vol.13, issue.2, p.5340414, 2017. ,
Crohn's disease susceptibility genes are associated with leprosy in the Vietnamese population, J Infect Dis, vol.206, issue.11, pp.1763-1770, 2012. ,
Pauci-and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases, PLoS Negl Trop Dis, vol.10, issue.5, p.4878860, 2016. ,
Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease, Proc Natl Acad Sci, vol.116, issue.31, pp.15616-15640, 2019. ,
,
Determining performance characteristics of an NGS-based HLA typing method for clinical applications, HLA, vol.87, issue.3, pp.141-52, 2016. ,
Omixon HLA Twin RUO-2.1.4: Handbook ,
IPD-IMGT/HLA Database, Nucleic Acids Res, vol.48, 2020. ,
Omixon HLA Twin RUO-2.5.0: User guide ,
Imputing amino acid polymorphisms in human leukocyte antigens, PLoS One, vol.8, issue.6, p.3675122, 2013. ,
R: A language and environment for statistical computing. R Foundation for Statistical Computing, 2020. ,
Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets, Hum Genet, vol.131, issue.5, p.3325408, 2012. ,
Second-generation PLINK: rising to the challenge of larger and richer datasets, Gigascience, vol.4, p.4342193, 2015. ,
A new look at the statistical model identification, IEEE Transactions on Automatic Control, vol.19, issue.6, pp.716-739, 1974. ,
Model selection and multimodel inference: a practical information-theoretic approach, 2002. ,
A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals, Am J Hum Genet, vol.84, issue.2, pp.210-233, 2009. ,
epitools: Epidemiology Tools. R package version 0.5-10, 2017. ,
The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data, PLoS One, vol.5, issue.4, p.2860502, 2010. ,
Construction of a population-specific HLA imputation reference panel and its application to Graves' disease risk in Japanese, Nat Genet, vol.47, issue.7, pp.798-802, 2015. ,
UCSF Chimera-a visualization system for exploratory research and analysis, J Comput Chem, vol.25, issue.13, pp.1605-1617, 2004. ,
Bidirectional binding of invariant chain peptides to an MHC class II molecule, Proc Natl Acad Sci, vol.107, issue.51, p.3009805, 2010. ,
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion, J Exp Med, vol.200, issue.1, pp.13-24, 2004. ,
, , p.2213310
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes, Nat Immunol, vol.13, issue.3, p.3378510, 2012. ,
Variation in MICA and MICB genes and enhanced susceptibility to paucibacillary leprosy in South India, Hum Mol Genet, vol.15, issue.19, pp.2880-2887, 2006. ,
Study of HLA class II alleles by PCR oligotyping in leprosy patients from north India, Tissue Antigens, vol.42, issue.3, p.8284786, 1993. ,
Leprosy associated with HLA-DR2 and DQw1 in the population of northern Thailand, Tissue Antigens, vol.26, issue.4, p.3878012, 1985. ,
HLA-DRB1*04 and DRB1*10 are associated with resistance and susceptibility, respectively, in Brazilian and Vietnamese leprosy patients, Genes Immun, vol.8, issue.4, pp.320-324, 2007. ,
Associations between HLA-DRB1 alleles and leprosy in an Indonesian population, Int J Lepr Other Mycobact Dis, vol.65, issue.2, pp.190-196, 1997. ,
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis, Nat Genet, vol.47, issue.2, p.4310771, 2015. ,
Relationship of HLA-DRB1 gene polymorphism with susceptibility to pulmonary tuberculosis: updated meta-analysis, Int J Tuberc Lung Dis, vol.19, issue.7, pp.841-850, 2015. ,
Associations of HLA-A, -B and -DRB1 types with oral diseases in Swiss adults, PLoS One, vol.9, issue.7, p.4114782, 2014. ,
HLA-DRB1*12 is associated with protection against complicated typhoid fever, independent of tumour necrosis factor alpha, Eur J Immunogenet, vol.29, issue.4, 2002. ,
Human leukocyte antigens in forms of leprosy among Japanese patients, Int J Lepr Other Mycobact Dis, vol.68, issue.1, pp.49-56, 2000. ,
Association of HLA-DRB1*0405 with resistance to multibacillary leprosy in Taiwanese, Hum Immunol, vol.71, issue.7, pp.712-718, 2010. ,
Variation at HLA-DRB1 is associated with resistance to enteric fever, Nat Genet, vol.46, issue.12, p.5099079, 2014. ,
Characteristics of Japanese inflammatory bowel disease susceptibility loci, Journal of Gastroenterology, vol.49, issue.8, pp.1217-1247, 2013. ,
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects, PLoS Genet, vol.9, issue.11, p.3836799, 2013. ,
Association of Parkinson disease with structural and regulatory variants in the HLA region, Am J Hum Genet, vol.93, issue.5, p.3824116, 2013. ,
T cells from patients with Parkinson's disease recognize alpha-synuclein peptides, Nature, vol.546, issue.7660, p.5626019, 2017. ,
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease, Sci Transl Med, vol.10, issue.423, p.6028002, 2018. ,
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans, Am J Hum Genet, vol.91, issue.5, p.3487133, 2012. ,
Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity, Nat Commun, vol.9, issue.1, p.6156406, 2018. ,
Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations, PLoS Biol, vol.17, issue.1, p.6372212, 2019. ,
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1, Nature, vol.364, issue.6432, pp.33-42, 1993. ,
HLA-DQ beta gene contributes to susceptibility and resistance to insulindependent diabetes mellitus, Nature, vol.329, issue.6140, pp.599-604, 1987. ,
Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk, Nat Genet, vol.47, issue.8, pp.898-905, 2015. ,
, , p.4930791
Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis, PLoS One, vol.13, issue.3, p.5832312, 2018. ,
Zooming into the binding groove of HLA molecules: which positions and which substitutions change peptide binding most?, Epub 2015/ 06/05, vol.67, p.4498290, 2015. ,