The emerging hallmarks of cancer metabolism, Cell Metab, vol.23, pp.27-47, 2016. ,
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?, Nat. Rev. Cancer, vol.16, pp.635-649, 2016. ,
Fasting and cancer: molecular mechanisms and clinical application, Nat. Rev. Cancer, vol.18, pp.707-719, 2018. ,
Metabolite sensing and signaling in cell metabolism, Signal Transduct. Target. Ther, vol.3, p.30, 2018. ,
Protein acetylation and acetyl coenzyme a metabolism in budding yeast, Eukaryot. Cell, vol.13, pp.1472-1483, 2014. ,
Acetyl coenzyme A: a central metabolite and second messenger, Cell Metab, vol.21, pp.805-821, 2015. ,
The rate of glycolysis quantitatively mediates specific histone acetylation sites, Cancer Metab, vol.3, p.10, 2015. ,
Acetyl-CoA carboxylase regulates global histone acetylation, J. Biol. Chem, vol.287, pp.23865-23876, 2012. ,
Spatiotemporal control of acetyl-CoA metabolism in chromatin regulation, Trends Biochem. Sci, vol.43, pp.61-74, 2018. ,
ATP-citrate lyase links cellular metabolism to histone acetylation, Science, vol.324, pp.1076-1080, 2009. ,
Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes, Mol. Cell, vol.42, pp.426-437, 2011. ,
A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states, Mol. Biol. Cell, vol.29, pp.2243-2258, 2018. ,
Acetyl-CoA and the regulation of metabolism: mechanisms and consequences, Curr. Opin. Cell Biol, vol.33, pp.125-131, 2015. ,
Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae, Curr. Genet, vol.56, pp.1-32, 2010. ,
The Warburg and Crabtree effects: on the origin of cancer cell energy metabolism and of yeast glucose repression, Biochim. Biophys. Acta, vol.1807, pp.568-576, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00520968
Regulation of subtelomeric silencing during stress response, Mol. Cell, vol.10, pp.1295-1305, 2002. ,
Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation, Nucleic Acids Res, vol.37, pp.3699-3713, 2009. ,
RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae, Genes Dev, vol.7, pp.1146-1159, 1993. ,
A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools, Mol. Cell, vol.2, pp.329-340, 1998. ,
Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity, Science, vol.316, pp.1916-1919, 2007. ,
Epigenetic silencing mediates mitochondria stress-induced longevity, Cell Metab, vol.17, pp.954-964, 2013. ,
Cross-talk between carbon metabolism and the DNA damage response in S. cerevisiae, Cell Rep, vol.12, pp.1865-1875, 2015. ,
PP2A controls genome integrity by integrating nutrientsensing and metabolic pathways with the DNA damage response, Mol. Cell, vol.67, pp.266-281, 2017. ,
Cell cycle-and ribonucleotide reductasedriven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression, Cell Cycle, vol.6, pp.2048-2057, 2007. ,
SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase, Mol. Cell Biol, vol.13, pp.5829-5842, 1993. ,
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways, Science, vol.271, pp.357-360, 1996. ,
A Rad53 kinase-dependent surveillance mechanism that regulates histone protein levels in S. cerevisiae, Cell, vol.115, pp.537-549, 2003. ,
Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis, Nat. Cell Biol, vol.11, pp.925-933, 2009. ,
Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation, Proc. Natl Acad. Sci. USA, vol.111, pp.14124-14129, 2014. ,
Regulation of DNA replication-coupled histone gene expression, Oncotarget, vol.8, pp.95005-95022, 2017. ,
Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry, Genes Dev, vol.12, pp.456-461, 1998. ,
Phosphoproteomics reveals distinct modes of Mec1/ATR signaling during DNA replication, Mol. Cell, vol.57, pp.1124-1132, 2015. ,
A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage, Mol. Cell, vol.17, pp.709-720, 2005. ,
Live imaging of telomeres: yKu and Sir proteins define redundant telomereanchoring pathways in yeast, Curr. Biol, vol.12, pp.2076-2089, 2002. ,
The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores, Cell, vol.146, pp.233-246, 2011. ,
Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants, Cell, vol.134, pp.1066-1078, 2008. ,
Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins, PLoS Genet, vol.14, p.1007418, 2018. ,
Dynamics of histone acetylation in Saccharomyces cerevisiae, Biochemistry, vol.40, pp.2599-2605, 2001. ,
Elevated recombination rates in transcriptionally active DNA, Cell, vol.56, pp.619-630, 1989. ,
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response, Mol. Cell Biol, vol.28, pp.358-375, 2008. ,
Yeast glucose pathways converge on the transcriptional regulation of trehalose biosynthesis, BMC Genomics, vol.13, p.239, 2012. ,
Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates, Nat. Struct. Mol. Biol, vol.24, pp.99-107, 2017. ,
Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling, Genes Dev, vol.32, pp.822-835, 2018. ,
NPAT expression is regulated by E2F and is essential for cell cycle progression, Mol. Cell Biol, vol.23, pp.2821-2833, 2003. ,
Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1, Nat. Struct. Mol. Biol, vol.12, pp.794-800, 2005. ,
Targeting Sir proteins to sites of action: a general mechanism for regulated repression, Cold Spring Harb. Symp. Quant. Biol, vol.63, pp.401-412, 1998. ,
Transcriptional regulation at the yeast nuclear envelope, Nucleus, vol.4, pp.379-389, 2013. ,
ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress, Cell, vol.158, pp.633-646, 2014. ,
Critical role of histone turnover in neuronal transcription and plasticity, Neuron, vol.87, pp.77-94, 2015. ,
Driving the cell cycle through metabolism, Annu. Rev. Cell Dev. Biol, vol.28, pp.59-87, 2012. ,
Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes, Science, vol.310, pp.1152-1158, 2005. ,
Chromosome 6p amplification and cancer progression, J. Clin. Pathol, vol.60, pp.1-7, 2007. ,
Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition, Proc. Natl Acad. Sci. USA, vol.113, pp.12238-12243, 2016. ,
Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients, Sci. Rep, vol.7, p.16495, 2017. ,
The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells, Cancer Lett, vol.396, pp.42-52, 2017. ,
Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells, Cell Div, vol.10, p.1, 2015. ,
Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma, Blood, vol.118, pp.493-498, 2011. ,
Characterization of the activation domain of the Rad53 checkpoint kinase, Cell Cycle, vol.7, pp.493-499, 2008. ,
New method to detect histone acetylation levels by flow cytometry, Cytometry A, vol.66, pp.52-61, 2005. ,
Jalview Version 2-a multiple sequence alignment editor and analysis workbench, Bioinformatics, vol.25, pp.1189-1191, 2009. ,
Integrated assessment and prediction of transcription factor binding, PLoS Comput. Biol, vol.2, p.70, 2006. ,
Exploring the functional landscape of gene expression: directed search of large microarray compendia, Bioinformatics, vol.23, pp.2692-2699, 2007. ,
Chromosome arm length and nuclear constraints determine the dynamic relationship of yeast subtelomeres, Proc. Natl Acad. Sci. USA, vol.107, pp.2025-2030, 2010. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02082757
Significance analysis of microarrays applied to the ionizing radiation response, Proc. Natl Acad. Sci. USA, vol.98, pp.5116-5121, 2001. ,
A versatile LC-MS/MS approach for comprehensive, quantitative analysis of central metabolic pathways, Wellcome open Res, vol.3, p.122, 2018. ,
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing, 2020. ,
URL : https://hal.archives-ouvertes.fr/inserm-02950793