Reply to the 'Comment on "Investigation of Zr(IV) and 89 Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

François Guérard; Yong-Sok Lee; Raphaël Tripier; Lawrence Szajek; Jeffrey Deschamps; Martin Brechbiel

doi:10.1039/d0cc03594g

Journal articles

Reply to the 'Comment on "Investigation of Zr(IV) and 89 Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

François Guérard ¹ Yong-Sok Lee ² Raphaël Tripier ^{3, *} Lawrence Szajek ² Jeffrey Deschamps ⁴ Martin Brechbiel ⁵

* Corresponding author

1 CRCINA-ÉQUIPE 13 - Nuclear Oncology

CRCINA - Centre de Recherche en Cancérologie et Immunologie Nantes-Angers

2 NIH - National Institutes of Health [Bethesda]

3 CEMCA - Chimie, Electrochimie Moléculaires et Chimie Analytique

4 U.S. Naval Research Laboratory [Washington, DC, USA]

5 NCI-NIH - National Cancer Institute [Bethesda]

Abstract : The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr4+ by considering polynuclear species. Placed in the context of nuclear medicine where such aggregates are unlikely and considering recent literature data, this however points out that no clear agreement exists to describe such complex formation.

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Journal articles

Domain :

Life Sciences [q-bio] / Cancer

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https://www.hal.inserm.fr/inserm-02947405
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Submitted on : Thursday, September 24, 2020 - 8:21:27 AM
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Reply to the 'Comment on "Investigation of Zr(IV) and 89 Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

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Reply to the 'Comment on "Investigation of Zr(IV) and 89 Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

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