M. Masuda and T. Yamada, Signaling pathway profiling by reverse-phase protein array for personalized cancer medicine, Biochim. Biophys. Acta Proteins Proteomics, vol.1854, pp.65-657, 2015.

J. P. Shapiro, S. Biswas, A. S. Merchant, and A. Satoskar, A quantitative proteomic workflow for characterization of frozen clinical biopsies: laser capture microdissection coupled with label-free mass spectrometry, J. Proteomics, vol.77, pp.433-440, 2012.

V. Kertesz, G. J. Van-berkel, K. G. Berkel, and . Van, Fully automated liquid extraction-based surface sampling and ionization using a chip-based robotic nanoelectrospray platform, J. Mass Spectrom, vol.45, pp.252-260, 2010.

V. Kertesz, N. Paranthaman, P. Moench, and A. Catoire, Liquid microjunction surface sampling of acetaminophen, terfenadine and their metabolites in thin tissue sections, Bioanalysis, vol.6, pp.2599-2606, 2014.

D. Eikel, M. Vavrek, S. Smith, and C. Bason, Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example, Rapid Commun. Mass Spectrom, vol.25, pp.3587-3596, 2011.

D. Eikel and J. Henion, Liquid extraction surface analysis (LESA) of food surfaces employing chip-based nanoelectrospray mass spectrometry, Rapid Commun. Mass Spectrom, vol.25, pp.2345-2354, 2011.

M. Himmelsbach, E. Varesio, and G. Hopfgartner, Liquid extraction surface analysis (LESA) of hydrophobic TLC plates coupled to chip-based nanoelectrospray high-resolution mass spectrometry, Chimia (Aarau), vol.68, pp.150-154, 2014.

S. H. Brown, L. H. Huxtable, M. D. Willcox, S. J. Blanksby, and T. W. Mitchell, Automated surface sampling of lipids from worn contact lenses coupled with tandem mass spectrometry, Analyst, vol.138, pp.1316-1320, 2013.

J. Quanico, J. Franck, C. Dauly, and K. Strupat, Development of liquid microjunction extraction strategy for improving protein identification from tissue sections, J. Proteomics, vol.79, pp.200-218, 2013.

M. Wisztorski, B. Fatou, J. Franck, and A. Desmons, Microproteomics by liquid extraction surface analysis: application to FFPE tissue to study the fimbria region of tubo-ovarian cancer, Proteomics Clin. Appl, vol.7, pp.234-240, 2013.

R. L. Edwards, A. J. Creese, M. Baumert, and P. Griffiths, Hemoglobin variant analysis via direct surface sampling of dried blood spots coupled with high-resolution mass spectrometry, Anal. Chem, vol.83, pp.2265-2270, 2011.

R. L. Edwards, P. Griffiths, J. Bunch, and H. J. Cooper, Topdown proteomics and direct surface sampling of neonatal dried blood spots: diagnosis of unknown hemoglobin variants, J. Am. Soc. Mass Spectrom, vol.23, pp.1921-1930, 2012.

R. L. Edwards, P. Griffiths, J. Bunch, and H. J. Cooper, Compound heterozygotes and beta-thalassemia: top-down mass spectrometry for detection of hemoglobinopathies, vol.14, pp.1232-1238, 2014.

E. C. Randall, J. Bunch, and H. J. Cooper, Direct analysis of intact proteins from Escherichia coli colonies by liquid extraction surface analysis mass spectrometry, Anal. Chem, vol.86, pp.10504-10510, 2014.

J. Sarsby, N. J. Martin, P. F. Lalor, J. Bunch, and H. J. Cooper, Top-down and bottom-up identification of proteins by liquid extraction surface analysis mass spectrometry of healthy and diseased human liver tissue, J. Am. Soc. Mass Spectrom, vol.25, pp.1953-1961, 2014.

J. R. Wi?niewski, A. Zougman, N. Nagaraj, and M. Mann, Universal sample preparation method for proteome analysis, Nat. Methods, vol.6, pp.359-362, 2009.

J. Cox and M. Mann, MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification, Nat. Biotechnol, vol.26, pp.1367-1372, 2008.

J. Cox, N. Neuhauser, A. Michalski, and R. A. Scheltema, Andromeda: a peptide search engine integrated into the MaxQuant environment, J. Proteome Res, vol.10, pp.1794-1805, 2011.

J. A. Vizcaíno, E. W. Deutsch, R. Wang, and A. Csordas, ProteomeXchange provides globally coordinated proteomics data submission and dissemination, Nat. Biotechnol, vol.32, pp.223-226, 2014.

J. A. Vizcaíno, R. G. Côté, A. Csordas, and J. A. Dianes, The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013, Nucleic Acids Res, vol.41, pp.1063-1069, 2013.

A. I. Saeed, V. Sharov, J. White, and J. Li, TM4: a free, open-source system for microarray data management and analysis, Biotechniques, vol.34, pp.374-378, 2003.

J. Herrero, A. Valencia, and J. Dopazo, A hierarchical unsupervised growing neural network for clustering gene expression patterns, Bioinformatics, vol.17, pp.126-162, 2001.

V. Kertesz and G. J. Van-berkel, Sampling reliability, spatial resolution, spatial precision, and extraction efficiency in droplet-based liquid microjunction surface sampling, Rapid Commun. Mass Spectrom, vol.28, pp.1553-1560, 2014.

K. Akiyama, S. Ichinose, A. Omori, Y. Sakurai, and H. Asou, Study of expression of myelin basic proteins (MBPs) in developing rat brain using a novel antibody reacting with four major isoforms of MBP, J. Neurosci. Res, vol.68, pp.19-28, 2002.

M. F. Ciaccio, J. P. Wagner, C. Chuu, D. A. Lauffenburger, and R. B. Jones, Systems analysis of EGF receptor signaling dynamics with microwestern arrays, Nat. Methods, vol.7, pp.148-155, 2010.

C. P. Paweletz, L. Charboneau, V. E. Bichsel, and N. L. Simone, Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front, Oncogene, vol.20, pp.1981-1989, 2001.

R. Lemaire, M. Wisztorski, . Desmons, and J. C. Tabet, MALDI-MS direct tissue analysis of proteins: improving signal sensitivity using organic treatments, Anal. Chem, vol.78, pp.7145-7153, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00086901

D. Szklarczyk, A. Franceschini, S. Wyder, and K. Forslund, STRING v10: protein-protein interaction networks, integrated over the tree of life, Nucleic Acids Res, vol.43, pp.447-452, 2015.

J. Franck, J. Quanico, M. Wisztorski, and R. Day, Quantification-based mass spectrometry imaging of proteins by parafilm assisted microdissection, Anal. Chem, vol.85, pp.8127-8134, 2013.

Z. Liu, S. F. Yan, J. R. Walker, and T. A. Zwingman, Study of gene function based on spatial co-expression in a highresolution mouse brain atlas, BMC Syst. Biol, 2007.

L. I. Benowitz and A. Routtenberg, GAP-43: an intrinsic determinant of neuronal development and plasticity, Trends Neurosci, vol.20, pp.84-91, 1997.

P. W. Frankland, C. O'brien, M. Ohno, A. Kirkwood, and A. J. Silva, Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory, Nature, vol.411, pp.309-313, 2001.

C. C. Ouimet, T. L. Mcguinness, and P. Greengard, Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain, Proc. Natl. Acad. Sci. U S A, vol.81, pp.5604-5608, 1984.

N. E. Erondu and M. B. Kennedy, Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain, J. Neurosci, vol.5, pp.3270-3277, 1985.

N. Liu, Regional distribution of protein kinases in normal and odor-deprived mouse olfactory bulbs, Chem. Senses, vol.25, pp.401-406, 2000.