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Parafilm-assisted microdissection: a sampling method for mass spectrometry-based identification of differentially expressed prostate cancer protein biomarkers

Abstract : Mass spectrometry-based methods for prostate cancer biomarker discovery are hampered by their low-throughput capabilities because of extensive sample preparation. We present the parafilm-assisted microdissection technique coupled with label-free quantification and bioinformatics analysis as a means to evaluate directly protein expression changes on benign and tumor regions.
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https://www.hal.inserm.fr/inserm-02940232
Contributor : Michel Salzet <>
Submitted on : Wednesday, September 16, 2020 - 10:52:07 AM
Last modification on : Tuesday, November 3, 2020 - 2:24:02 PM

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J. Quanico, J. Franck, J. Gimeno, R. Sabbagh, Michel Salzet, et al.. Parafilm-assisted microdissection: a sampling method for mass spectrometry-based identification of differentially expressed prostate cancer protein biomarkers. Chemical Communications, Royal Society of Chemistry, 2015, 51 (22), pp.4564-4567. ⟨10.1039/c4cc08331h⟩. ⟨inserm-02940232⟩

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