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Global divergence from WHO treatment guidelines for neonatal and paediatric sepsis

Charlotte Jackson 1 Yingfen Hsia 1 Romain Basmaci 2, 3 Julia Bielicki 1, 4 Paul Heath 1 Ann Versporten 5 Herman Goossens 5 Mike Sharland 1
1 Paediatric Infectious Diseases Research Group [London, UK]
2 IAME (UMR_S_1137 / U1137) - Infection, Anti-microbiens, Modélisation, Evolution
3 Service de Pédiatrie-Urgences [Hopital Louis Mourier - APHP, Colombes]
4 Paediatric Pharmacology [Basel, Switzerland]
5 VAXINFECTIO - Vaccine & Infectious Disease Institute [Antwerp, Belgium]
Abstract : We used data from 2 global point prevalence surveys of antibiotic prescribing to describe the treatment of sepsis in hospitalized neonates and children. One hundred eighty-five of 824 neonates (22.5%) and 9/786 children (1.1%) received a World Health Organization-recommended first-line treatment; of the remainder, 9/639 neonates (1.4%) and 102/777 children (13.1%) received a World Health Organization-recommended second-line treatment. Reasons for this low adherence to guidance should be explored.
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https://www.hal.inserm.fr/inserm-02935761
Contributor : Emmanuelle Comets <>
Submitted on : Thursday, September 10, 2020 - 4:18:40 PM
Last modification on : Thursday, April 15, 2021 - 3:08:18 PM

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INSERM | SORBONNE-PARIS-NORD | UNIV-PARIS13 | UP-SANTE | USPC

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Charlotte Jackson, Yingfen Hsia, Romain Basmaci, Julia Bielicki, Paul Heath, et al.. Global divergence from WHO treatment guidelines for neonatal and paediatric sepsis. Pediatric Infectious Disease Journal, Lippincott, Williams & Wilkins, 2019, 38 (11), pp.1104-1106. ⟨10.1097/INF.0000000000002433⟩. ⟨inserm-02935761⟩

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