A. Iannello, T. W. Thompson, M. Ardolino, A. Marcus, and D. H. Raulet, Immunosurveillance and immunotherapy of tumors by innate immune cells, Curr. Opin. Immunol, vol.38, pp.52-58, 2016.

S. N. Waggoner, S. D. Reighard, I. E. Gyurova, S. A. Cranert, S. E. Mahl et al., Roles of natural killer cells in antiviral immunity, Curr. Opin. Virol, vol.16, pp.15-23, 2016.

K. Kärre, MHC gene control of the natural killer system at the level of the target and the host, Semin. Cancer Biol, vol.2, pp.295-309, 1991.

N. Anfossi, P. André, S. Guia, C. S. Falk, S. Roetynck et al., Human NK cell education by inhibitory receptors for MHC class I, Immunity, vol.25, pp.331-342, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00091535

J. E. Boudreau and K. C. Hsu, Natural killer cell education in human health and disease, Curr. Opin. Immunol, vol.50, pp.102-111, 2018.

, Cancers, vol.12, p.18, 1927.

V. M. Braud, D. S. Allan, C. A. O'callaghan, K. Söderström, A. D'andrea et al., HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C, Nature, vol.391, pp.795-799, 1998.

G. Del-zotto, E. Marcenaro, P. Vacca, S. Sivori, D. Pende et al., Markers and function of human NK cells in normal and pathological conditions: Markers and Function Of Human Nk Cells, Cytometry B Clin. Cytom, vol.92, pp.100-114, 2017.

L. Chiossone, M. Vienne, Y. M. Kerdiles, and E. Vivier, Natural killer cell immunotherapies against cancer: Checkpoint inhibitors and more, Semin. Immunol, vol.31, pp.55-63, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01764667

S. Gaggero, M. Bruschi, A. Petretto, M. Parodi, G. Del-zotto et al.,

A. Niehrs, W. F. Garcia-beltran, P. J. Norman, G. M. Watson, A. Hölzemer et al., A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44, Nat. Immunol, vol.20, pp.1129-1137, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02426901

A. D. Barrow, M. A. Edeling, V. Trifonov, J. Luo, P. Goyal et al., Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor. Cell, vol.172, pp.534-548, 2018.

S. Mastaglio, E. Wong, T. Perera, J. Ripley, P. Blombery et al., Natural killer receptor ligand expression on acute myeloid leukemia impacts survival and relapse after chemotherapy, Blood Adv, vol.2, pp.335-346, 2018.

D. Pende, G. M. Spaggiari, S. Marcenaro, S. Martini, P. Rivera et al., Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: Evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112), Blood, vol.105, pp.2066-2073, 2005.

C. Willem, D. R. Makanga, T. Guillaume, B. Maniangou, N. Legrand et al., Impact of KIR/HLA Incompatibilities on NK Cell Reconstitution and Clinical Outcome after T Cell-Replete Haploidentical Hematopoietic Stem Cell Transplantation with Posttransplant Cyclophosphamide, J. Immunol, vol.202, pp.2141-2152, 2019.
URL : https://hal.archives-ouvertes.fr/inserm-02080762

P. Parham, Co-evolution of lymphocyte receptors with MHC class I, Immunol. Rev, vol.267, pp.1-5, 2015.

N. K. Björkström, P. Riese, F. Heuts, S. Andersson, C. Fauriat et al., Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education, Blood, vol.116, pp.3853-3864, 2010.

C. M. Nielsen, M. J. White, M. R. Goodier, and E. M. Riley, Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease. Front

A. Pfefferle, B. Jacobs, H. Netskar, E. H. Ask, S. Lorenz et al., Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity, Cell Rep, vol.29, pp.2284-2294, 2019.

F. Cichocki, B. Grzywacz, and J. S. Miller, Human NK Cell Development: One Road or Many? Front

V. Béziat, L. L. Liu, J. Malmberg, M. A. Ivarsson, E. Sohlberg et al., NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs, Blood, vol.121, pp.2678-2688, 2013.

M. Della-chiesa, L. Muccio, and A. Moretta, CMV induces rapid NK cell maturation in HSCT recipients, Immunol. Lett, vol.155, pp.11-13, 2013.

B. Foley, S. Cooley, M. R. Verneris, J. Curtsinger, X. Luo et al., Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C + NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen, J. Immunol, vol.189, pp.5082-5088, 2012.

Z. Djaoud, G. David, C. Bressollette, C. Willem, P. Rettman et al., Amplified NKG2C+ NK Cells in Cytomegalovirus (CMV) Infection Preferentially Express Killer Cell Ig-like Receptor 2DL: Functional Impact in Controlling CMV-Infected Dendritic Cells, J. Immunol, vol.191, pp.2708-2716, 2013.

Q. Hammer, T. Rückert, E. M. Borst, J. Dunst, A. Haubner et al., Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells, Nat. Immunol, vol.19, pp.453-463, 2018.

T. A. Fehniger and M. A. Cooper, Harnessing NK Cell Memory for Cancer Immunotherapy, Trends Immunol, vol.37, pp.877-888, 2016.

G. F. Torelli, N. Peragine, S. Raponi, D. Pagliara, M. S. De-propris et al., Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells, Haematologica, vol.99, pp.1248-1254, 2014.

F. Locatelli, F. Moretta, L. Brescia, and P. Merli, Natural killer cells in the treatment of high-risk acute leukaemia, Semin. Immunol, vol.26, pp.173-179, 2014.

C. Sweeney and P. Vyas, The Graft-Versus-Leukemia Effect in AML, Front. Oncol, vol.9, 2019.

A. M. Paczulla, K. Rothfelder, S. Raffel, M. Konantz, J. Steinbacher et al., Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion, Nature, vol.572, pp.254-259, 2019.

G. David, Z. Djaoud, C. Willem, N. Legrand, P. Rettman et al., Large Spectrum of HLA-C Recognition by Killer Ig-like Receptor (KIR)2DL2 and KIR2DL3 and Restricted C1 Specificity of KIR2DS2: Dominant Impact of KIR2DL2/KIR2DS2 on KIR2D NK Cell Repertoire Formation, J. Immunol, vol.191, pp.4778-4788, 2013.

P. Hansasuta, T. Dong, H. Thananchai, M. Weekes, C. Willberg et al., Recognition of HLA-A3 and HLA-A11 by KIR3DL2 is peptide-specific, Eur. J. Immunol, vol.34, pp.1673-1679, 2004.

M. Morvan, G. David, V. Sébille, A. Perrin, K. Gagne et al., Autologous and allogeneic HLA KIR ligand environments and activating KIR control KIR NK-cell functions, Eur. J. Immunol, vol.38, pp.3474-3486, 2008.

C. Fauriat, S. Andersson, A. T. Björklund, M. Carlsten, M. Schaffer et al., Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A KIR Haplotype, J. Immunol, vol.181, pp.6010-6019, 2008.

J. Yu, G. Heller, J. Chewning, S. Kim, W. M. Yokoyama et al., Hierarchy of the Human Natural Killer Cell Response Is Determined by Class and Quantity of Inhibitory Receptors for Self-HLA-B and HLA-C Ligands, J. Immunol, vol.179, pp.5977-5989, 2007.

H. G. Hilton, L. A. Guethlein, A. Goyos, N. Nemat-gorgani, D. A. Bushnell et al., Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes, J. Immunol, vol.195, pp.3160-3170, 2015.

M. Morvan, C. Willem, K. Gagne, N. Kerdudou, G. David et al., Phenotypic and Functional Analyses of KIR3DL1+ and KIR3DS1+ NK Cell Subsets Demonstrate Differential Regulation by Bw4 Molecules and Induced KIR3DS1 Expression on Stimulated NK Cells, J. Immunol, vol.182, pp.6727-6735, 2009.

J. P. Goodridge, B. Önfelt, and K. Malmberg, Newtonian cell interactions shape natural killer cell education, Immunol. Rev, vol.267, pp.197-213, 2015.

O. Hatton, D. M. Strauss-albee, N. Q. Zhao, M. D. Haggadone, J. S. Pelpola et al., NKG2A-Expressing Natural Killer Cells Dominate the Response to Autologous Lymphoblastoid Cells Infected with Epstein-Barr Virus, Front. Immunol, vol.7, 2016.

E. Forslund, E. Sohlberg, M. Enqvist, P. E. Olofsson, K. Malmberg et al., Microchip-Based Single-Cell Imaging Reveals That CD56 dim CD57 ? KIR ? NKG2A + NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56 dim CD57 ? KIR ? NKG2A ? NK Cells, J. Immunol, vol.195, pp.3374-3381, 2015.

A. Russo, G. Oliveira, S. Berglund, R. Greco, V. Gambacorta et al., NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: Dynamics and clinical implications, Blood, vol.131, pp.247-262, 2018.

A. Mancusi, L. Ruggeri, and A. Velardi, Haploidentical hematopoietic transplantation for the cure of leukemia: From its biology to clinical translation, Blood, vol.128, pp.2616-2623, 2016.

F. Locatelli, D. Pende, M. C. Mingari, A. Bertaina, M. Falco et al., Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: Role of alloreactive NK cells

S. Nguyen, N. Dhedin, J. Vernant, M. Kuentz, A. A. Jijakli et al., NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: Immaturity of NK cells and inhibitory effect of NKG2A override GvL effect, Blood, vol.105, pp.4135-4142, 2005.

J. J. Hodgins, S. T. Khan, M. M. Park, R. C. Auer, and M. Ardolino, Killers 2.0: NK Cell Therapies at the Forefront of Cancer Control, 2020.

L. Ruggeri, S. Parisi, E. Urbani, and A. Curti, Alloreactive Natural Killer Cells for the Treatment of Acute Myeloid Leukemia: From Stem Cell Transplantation to, Adoptive Immunotherapy. Front. Immunol, vol.6, 2015.

E. Liu, D. Marin, P. Banerjee, H. A. Macapinlac, P. Thompson et al., Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors, N. Engl. J. Med, 2020.

A. R. Manser, N. Scherenschlich, C. Thöns, H. Hengel, J. Timm et al., KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals, J. Immunol, vol.203, pp.2301-2309, 2019.

L. L. Liu, V. Béziat, V. Y. Oei, A. Pfefferle, M. Schaffer et al., Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells, Cancer Immunol. Res, vol.5, pp.654-665, 2017.

S. Lopez-verges, J. M. Milush, B. S. Schwartz, M. J. Pando, J. Jarjoura et al., Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection, Proc. Natl. Acad. Sci, vol.108, pp.14725-14732, 2011.

A. Merino, B. Zhang, P. Dougherty, X. Luo, J. Wang et al., Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming, J. Clin. Invest, vol.129, pp.3770-3785, 2019.

J. Y. Sun, L. Gaidulis, M. M. Miller, R. M. Goto, R. Rodriguez et al., Development of a multiplex PCR-SSP method for Killer-cell immunoglobulin-like receptor genotyping, Tissue Antigens, vol.64, pp.462-468, 2004.

G. Alter, J. M. Malenfant, and M. Altfeld, CD107a as a functional marker for the identification of natural killer cell activity, J. Immunol. Methods, vol.294, pp.15-22, 2004.

O. Penack, C. Gentilini, L. Fischer, A. M. Asemissen, C. Scheibenbogen et al., CD56dimCD16neg cells are responsible for natural cytotoxicity against tumor targets, Leukemia, vol.19, pp.835-840, 2005.

A. Sturn, J. Quackenbush, Z. Trajanoski, and . Genesis, Cluster analysis of microarray data, Bioinformatics, vol.18, pp.207-208, 2002.

K. C. Hsu, S. Chida, D. E. Geraghty, and B. Dupont, The killer cell immunoglobulin-like receptor (KIR) genomic region: Gene-order, haplotypes and allelic polymorphism, © 2020 by the authors. Licensee MDPI, vol.190, pp.40-52, 2002.