Skip to Main content Skip to Navigation
Journal articles

Potential of fibrates in the treatment of fatty acid oxidation disorders: Revival of classical drugs?

Abstract : Exposure to fibrates leads to normalization of fatty acid oxidation (FAO) in fibroblasts from patients with myopathic forms of CPT2 deficiency or VLCAD deficiency. Correction of FAO is related to a drug-induced increase of residual enzyme activity, and this could provide a new treatment strategy for these disorders.
Document type :
Journal articles
Complete list of metadatas

Cited literature [6 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-02896275
Contributor : Fatima Djouadi <>
Submitted on : Friday, July 10, 2020 - 1:54:05 PM
Last modification on : Friday, September 18, 2020 - 2:35:08 PM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Citation

F. Djouadi, F. Aubey, D. Schlemmer, S. Gobin, P. Laforet, et al.. Potential of fibrates in the treatment of fatty acid oxidation disorders: Revival of classical drugs?. Journal of Inherited Metabolic Disease, Springer Verlag, 2006, 29 (2-3), pp.341-342. ⟨10.1007/s10545-006-0266-3⟩. ⟨inserm-02896275⟩

Share

Metrics

Record views

27