Skip to Main content Skip to Navigation
Journal articles

Retinal Degenerations: From Cell Signaling to Cell Therapy; Pre-Clinical and Clinical Issues

Abstract : Extracellular signaling molecules have been implicated in the progression of Retinal Degeneration (RD). Gene regulatory events linked to the maintenance of retinal structure and function incorporate signaling cascades that may serve as therapeutic targets for some forms of blindness. This review shall focus on the evidence for non-cell-autonomous mechanisms that affect the pattern of degeneration seen in retinal dystrophies, the types of signals that may influence the course of degeneration and finally with the related prospects for retinal-therapies.
Complete list of metadatas

Cited literature [119 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-02894199
Contributor : Therese Cronin <>
Submitted on : Wednesday, July 8, 2020 - 5:58:01 PM
Last modification on : Saturday, July 11, 2020 - 3:26:21 AM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Citation

Thérèse Cronin, Thierry Léveillard, José-Alain Sahel. Retinal Degenerations: From Cell Signaling to Cell Therapy; Pre-Clinical and Clinical Issues. Current Gene Therapy, Bentham Science Publishers, 2007, 7 (2), pp.121-129. ⟨10.2174/156652307780363143⟩. ⟨inserm-02894199⟩

Share

Metrics

Record views

22