S. B. Hoath and D. G. Leahy, The organization of human epidermis: functional epidermal units and phi proportionality, J. Invest. Dermatol, vol.121, pp.1440-1446, 2003.

J. H. Christiansen, E. G. Coles, and D. G. Wilkinson, Molecular control of neural crest formation, migration and differentiation, Curr. Opin. Cell Biol, vol.12, pp.719-724, 2000.

C. Delevoye, M. S. Marks, and G. Raposo, Lysosome-related organelles as functional adaptations of the endolysosomal system, Curr. Opin. Cell Biol, vol.59, pp.147-158, 2019.

G. Raposo, D. Tenza, D. M. Murphy, J. F. Berson, and M. S. Marks, Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells, J. Cell Biol, vol.152, pp.809-823, 2001.

X. Wu and J. A. Hammer, Melanosome transfer: It is best to give and receive, Curr. Opin. Cell Biol, vol.29, pp.1-7, 2014.

Z. Abdel-malek, Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes, Pigment Cell Res, vol.7, pp.326-332, 1994.

T. Hirobe, Keratinocytes regulate the function of melanocytes, Dermatol. Sin, vol.32, pp.200-204, 2014.

A. Lo-cicero, Exosomes released by keratinocytes modulate melanocyte pigmentation, Nat. Commun, vol.6, p.7506, 2015.

S. A. D'mello, G. J. Finlay, B. C. Baguley, and M. E. Askarian-amiri, Signaling pathways in melanogenesis, Int. J. Mol. Sci, vol.17, p.1144, 2016.

A. Saldana-caboverde and L. Kos, Roles of endothelin signaling in melanocyte development and melanoma, Pigment Cell Melanoma Res, vol.23, pp.160-170, 2011.

R. Buscà and R. Ballotti, Cyclic AMP a key messenger in the regulation of skin pigmentation, Pigment Cell Res, vol.13, pp.60-69, 2000.

G. Scott, Rac and Rho: the story behind melanocyte dendrite formation, Pigment Cell Res, vol.15, pp.322-330, 2002.

G. Scott and S. Leopardi, The cAMP signaling pathway has opposing effects on Rac and Rho in B16F10 cells: Implications for dendrite formation in melanocytic cells, Pigment Cell Res, vol.16, pp.139-148, 2003.

G. E. Palade, Fine structure of blood capillaries, J. Appl. Phys, vol.24, p.1424, 1953.

E. Yamada, The fine structures of the gall bladder epithelium of the mouse, J. Biophys. Biochem. Cytol, vol.1, pp.445-458, 1955.

R. V. Stan, Structure of caveolae, Biochim. Biophys. Acta, vol.1746, pp.334-348, 2005.

T. M. Williams and M. P. Lisanti, The caveolin proteins, Genome Biol, vol.5, p.214, 2004.

Z. D. Nassar and M. O. Parat, Cavin family: new players in the biology of caveolae, Int. Rev. Cell Mol. Biol, vol.320, pp.235-305, 2015.

J. P. Cheng and B. J. Nichols, Caveolae: one function or many?, Trends Cell Biol, vol.26, pp.177-189, 2016.

C. Lamaze, N. Tardif, M. Dewulf, S. Vassilopoulos, and C. M. Blouin, The caveolae dress code: structure and signaling, Curr. Opin. Cell Biol, vol.47, pp.117-125, 2017.

R. D. Harvey and S. C. Calaghan, Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology, J. Mol. Cell Cardiol, vol.52, pp.366-375, 2012.

Y. Toya, C. Schwencke, J. Couet, M. P. Lisanti, and Y. Ishikawa, Inhibition of adenylyl cyclase by caveolin peptides, Endocrinology, vol.139, pp.2025-2031, 1998.

P. T. Wright, Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling, J. Mol. Cell Cardiol, vol.67, pp.38-48, 2014.

P. T. Wright, Cardiomyocyte membrane structure and cAMP compartmentation produce anatomical variation in ?2AR-cAMP responsiveness in murine hearts, Cell Rep, vol.23, pp.459-469, 2018.

B. Sinha, Cells respond to mechanical stress by rapid disassembly of caveolae, Cell, vol.144, pp.402-413, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00821331

H. P. Lo, The caveolin-Cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle, J. Cell Biol, vol.210, pp.833-849, 2015.

Y. Lim, Caveolae protect notochord cells against catastrophic mechanical failure during development, Curr. Biol, vol.27, 1968.

J. P. Cheng, Caveolae protect endothelial cells from membrane rupture during increased cardiac output, J. Cell Biol, vol.211, pp.53-61, 2015.

M. Dewulf, Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells, Nat. Commun, vol.10, p.1974, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02129168

S. Benito-martínez, Research techniques made simple: cell biology methods for the analysis of pigmentation, J. Investig. Dermatol, vol.140, pp.257-268, 2020.

W. J. Rappel and L. Edelstein-keshet, Mechanisms of cell polarization, Curr. Opin. Syst. Biol, vol.3, pp.43-53, 2017.

R. Wedlich-soldner and R. Li, Spontaneous cell polarization: undermining determinism, Nat. Cell Biol, vol.5, pp.267-270, 2003.

S. Mayor, R. G. Parton, and J. G. Donaldson, Clathrin-independent pathways of endocytosis, Cold Spring Harb. Perspect. Biol, vol.6, p.16758, 2014.

D. Studer, B. M. Humbel, and M. Chiquet, Electron microscopy of high pressure frozen samples: bridging the gap between cellular ultrastructure and atomic resolution, Histochem. Cell Biol, vol.130, pp.877-889, 2008.

T. Richter, High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions, Traffic, vol.9, pp.893-909, 2008.

N. Ali, Skin equivalents: skin from reconstructions as models to study skin development and diseases, Br. J. Dermatol, vol.173, pp.391-403, 2015.

J. Heuser, Three-dimensional visualization of coated vesicle formation in fibroblasts, J. Cell Biol, vol.84, pp.560-583, 1980.

J. A. Allen, Caveolin-1 and lipid microdomains regulate Gs trafficking and attenuate Gs/adenylyl cyclase signaling, Mol. Pharmacol, vol.76, pp.1082-1093, 2009.

T. N. Litvin, M. Kamenetsky, A. Zarifyan, J. Buck, and L. R. Levin, Kinetic properties of 'soluble' adenylyl cyclase: synergism between calcium and bicarbonate, J. Biol. Chem, vol.278, pp.15922-15926, 2003.

J. Lu, J. Zhang, Y. Wang, and Q. Sun, Caveolin-1 scaffolding domain peptides alleviate liver fibrosis by inhibiting TGF-?1/Smad signaling in mice, Int. J. Mol. Sci, vol.19, p.1729, 2018.

P. Weng, Caveolin-1 scaffolding domain peptides enhance antiinflammatory effect of heme oxygenase-1 through interrupting its interact with caveolin-1, Oncotarget, vol.8, pp.40104-40114, 2017.

G. Imokawa, Y. Yada, and M. Kimura, Signalling mechanisms of endothelininduced mitogenesis and melanogenesis in human melanocytes, Biochem. J, vol.314, pp.305-312, 1996.

Z. Abdel-malek, Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides, Proc. Natl Acad. Sci. USA, vol.92, pp.1789-1793, 1995.

J. P. Ebanks, R. R. Wickett, and R. E. Boissy, Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration, Int. J. Mol. Sci, vol.10, pp.4066-4087, 2009.

A. C. Theos, S. T. Truschel, G. Raposo, and M. S. Marks, The silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function, Pigment Cell Res, vol.18, pp.322-336, 2005.

S. R. Neves-zaph, Phosphodiesterase diversity and signal processing within cAMP signaling networks, Adv. Neurobiol, vol.17, pp.3-14, 2017.

K. A. Wojtal, D. Hoekstra, and S. C. Van-ijzendoorn, cAMP-dependent protein kinase A and the dynamics of epithelial cell surface domains: Moving membranes to keep in shape, BioEssays, vol.30, pp.146-155, 2008.

A. K. Howe, Regulation of actin-based cell migration by cAMP/PKA, Biochim. Biophys. Acta, vol.1692, pp.159-174, 2004.

S. Kippenberger, A. Bernd, J. Bereiter-hahn, A. Ramirez-bosca, and R. Kaufmann, The mechanism of melanocyte dendrite formation: the impact of differentiating keratinocytes, Pigment Cell Res, vol.11, pp.34-37, 1998.

A. Grande-garcía, Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases, J. Cell Biol, vol.177, pp.683-694, 2007.

P. Chugh and E. K. Paluch, The actin cortex at a glance, J. Cell Sci, vol.131, p.186254, 2018.

S. M. Heissler and D. J. Manstein, Nonmuscle myosin-2: mix and match, Cell Mol. Life Sci, vol.70, pp.1-21, 2013.

A. Diz-muñoz, D. A. Fletcher, and O. D. Weiner, Use the force: membrane tension as an organizer of cell shape and motility, Trends Cell Biol, vol.23, pp.47-53, 2013.

R. Tadokoro and Y. Takahashi, Intercellular transfer of organelles during body pigmentation, Curr. Opin. Genet. Dev, vol.45, pp.132-138, 2017.

A. Conde-perez, A caveolin-dependent and PI3K/AKT-independent role of PTEN in ?-catenin transcriptional activity, Nat. Commun, vol.6, p.8093, 2015.

R. S. Ostrom, Localization of adenylyl cyclase isoforms and G proteincoupled receptors in vascular smooth muscle cells: expression in caveolin-rich and noncaveolin domains, Mol. Pharmacol, vol.62, pp.983-992, 2002.

C. Gu, K. E. Smith, B. Hu, D. M. Cooper, and K. A. Fagan, Residence of adenylyl cyclase type 8 in caveolae is necessary but not sufficient for regulation by capacitative Ca 2+ entry, J. Biol. Chem, vol.277, pp.6025-6031, 2002.

B. M. Collins, M. J. Davis, J. F. Hancock, and R. G. Parton, Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?, Dev. Cell, vol.23, pp.11-20, 2012.

J. G. Goetz, Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis, Cell, vol.146, pp.148-163, 2011.

S. Averaimo, A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors, Nat. Commun, vol.7, p.12896, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01398119

B. P. Head, Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons, J. Biol. Chem, vol.286, pp.33310-33321, 2011.

A. Navarro, B. Anand-apte, and M. Parat, A role for caveolae in cell migration, FASEB J, vol.18, pp.1801-1811, 2004.

S. J. Gallagher, Beta-catenin inhibits melanocyte migration but induces melanoma metastasis, Oncogene, vol.32, pp.2230-2238, 2013.

J. C. Valencia, Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes, J. Cell Sci, vol.119, pp.1080-1091, 2006.

R. A. Newton, A. L. Cook, D. W. Roberts, J. H. Leonard, and R. A. Sturm, Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes, J. Invest. Dermatol, vol.127, pp.2216-2227, 2007.

N. C. Gauthier, M. A. Fardin, P. Roca-cusachs, and M. P. Sheetz, Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading, Proc. Natl Acad. Sci. USA, vol.108, pp.14467-14472, 2011.

A. Carè, I. Parolini, F. Felicetti, and M. Sargiacomo, Caveolins in Cancer Pathogenesis, Prevention and Therapy, pp.65-74, 2011.

I. L. Kruglikov and P. E. Scherer, Caveolin-1 as a pathophysiological factor and target in psoriasis, Aging Mech. Dis, vol.5, p.4, 2019.

L. Lobos-gonzález, L. Aguilar, G. Fernández, C. Sanhueza, and A. F. Quest, Advances in Malignant Melanoma -Clinical and Research Perspectives, 2019.

M. I. Lin, J. Yu, T. Murata, and W. C. Sessa, Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth, Cancer Res, vol.67, pp.2849-2856, 2007.

R. M. Mackie, Long-term health risk to the skin of ultraviolet radiation, Prog. Biophys. Mol. Biol, vol.92, pp.92-96, 2006.

R. Huang, An exploration of the role of microRNAs in psoriasis: a systematic review of the literature, Medicine, vol.94, p.2030, 2015.

M. Salducci, Factors secreted by irradiated aged fibroblasts induce solar lentigo in pigmented reconstructed epidermis, Pigment Cell Melanoma Res, vol.27, pp.502-504, 2014.

L. Ripoll, Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers, J. Cell Biol, vol.217, pp.2709-2726, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02349279

I. Hurbain, Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets, Proc. Natl Acad. Sci. USA, vol.105, pp.19726-19731, 2008.

I. Hurbain, M. Romao, P. Bergam, X. Heiligenstein, and G. Raposo, Analyzing lysosome-related organelles by electron microscopy, Methods Mol. Biol, vol.1594, pp.43-71, 2017.

D. N. Mastronarde, Dual-axis tomography: an approach with alignment methods that preserve resolution, J. Struct. Biol, vol.120, pp.343-352, 1997.

J. R. Kremer, D. N. Mastronarde, and J. R. Mcintosh, Computer visualization of three-dimensional image data using IMOD, J. Struct. Biol, vol.116, pp.71-76, 1996.

C. Sommer, C. Straehle, U. Kothe, F. A. Hamprecht, and . Ilastik, Interactive learning and segmentation toolkit, Proc. International Symposium on Biomedical Imaging 230-233, 2011.

L. D. Conceptualization, C. B. , C. G. , K. V. , G. R. et al.,