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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Florence Demenais 1 Patricia Margaritte-Jeannin 2 Kathleen Barnes 3 William Cookson 4 Janine Altmüller 5 Wei Ang R. Graham Barr Terri Beaty 6 Allan Becker 7 John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker 8 Klaus Bønnelykke Dorret Boomsma 9 Emmanuelle Bouzigon 10 Christopher Brightling 11 Myriam Brossard 2 Guy Brusselle 12 Esteban Burchard Kristin Burkart Andrew Bush 13 Moira Chan-Yeung Kian Fan Chung 14 Alexessander Couto Alves John Curtin Adnan Custovic 15 Denise Daley Johan de Jongste Blanca Del-Rio-Navarro Kathleen Donohue Liesbeth Duijts 16 Celeste Eng Johan Eriksson 17 Martin Farrall 18 Yuliya Fedorova Bjarke Feenstra Manuel Ferreira 19 Maxim Freidin 20 Zofia Gajdos Jim Gauderman 21 Ulrike Gehring 22 Frank Geller Jon Genuneit 23 Sina Gharib Frank Gilliland Raquel Granell 24 Penelope Graves 25 Daniel Gudbjartsson Tari Haahtela 26 Susan Heckbert Dick Heederik 27 Joachim Heinrich 28 Markku Heliövaara 29 John Henderson 30 Blanca Himes Hiroshi Hirose Joel Hirschhorn Albert Hofman 31 Patrick Holt Jouke Hottenga Thomas Hudson 32 Jennie Hui 33 Medea Imboden 34 Vladimir Ivanov Vincent Jaddoe 35 Alan James Christer Janson 36 Marjo-Riitta Järvelin 37 Deborah Jarvis 15 Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen 38 David Kantor Alexandra Karunas Elza Khusnutdinova 39 Gerard Koppelman 40 Anita Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar 41 Ashish Kumar 42 Mikko Kuokkanen Lies Lahousse 43 Tarja Laitinen 44 Catherine Laprise 45 Mark Lathrop 46 Susanne Lau 47 Young-Ae Lee 48 Terho Lehtimäki 49 Sébastien Letort 50 Albert Levin Guo Li 51 Liming Liang 52 Laura Loehr 53 Stephanie London 54 Daan Loth Ani Manichaikul Ingo Marenholz Fernando Martinez 25 Melanie Matheson Rasika Mathias 6 Kenji Matsumoto 55 Hamdi Mbarek Wendy Mcardle Mads Melbye 56 Erik Melen 57 Deborah Meyers 58 Sven Michel Hamida Mohamdi 59 Arthur Musk Rachel Myers Maartje Nieuwenhuis Emiko Noguchi 60 George O’connor Ludmila Ogorodova Cameron Palmer Aarno Palotie 61 Julie Park Craig Pennell Goran Pershagen 62 Alexey Polonikov Dirkje Postma 40 Nicole Probst-Hensch 34 Valery Puzyrev Benjamin Raby Olli Raitakari 38 Adaikalavan Ramasamy 63 Stephen Rich Colin Robertson Isabelle Romieu 64 Muhammad Salam Veikko Salomaa 65 Vivi Schlünssen 66 Robert Scott 67 Polina Selivanova Torben Sigsgaard 68 Angela Simpson 69 Valérie Siroux 70 Lewis Smith Maria Solodilova Marie Standl Kari Stefansson 71 David Strachan 72 Bruno Stricker 73 Atsushi Takahashi 74 Philip Thompson 75 Gudmar Thorleifsson 71 Unnur Thorsteinsdottir 71 Carla Tiesler Dara Torgerson 76 Tatsuhiko Tsunoda Andre Uitterlinden 31 Ralf van der Valk Amaury Vaysse 2 Sailaja Vedantam Andrea von Berg Erika von Mutius 77 Judith Vonk 40 Johannes Waage 78 Nick Wareham 79 Scott Weiss Wendy White Magnus Wickman 80 Elisabeth Widén 17 Gonneke Willemsen 81 L. Keoki Williams Inge Wouters James Yang Jing Hua Zhao 82 Miriam Moffatt 4 Carole Ober 83 Dan Nicolae 84
1 Fondation Jean-Dausset-CEPH, INSERM U946
2 Variabilité Génétique et Maladies Humaines
3 Department of Medicine [Aurora, CO, USA]
4 NHLI - National Heart and Lung Institute
5 CCG - Cologne Center for Genomics
6 JHU - Johns Hopkins University
7 Pediatrics and Child Health
8 University of Arizona
9 King‘s College London
10 Méthodologie statistique et épidémiologie génétique de maladies multifactorielles
11 Department of Respiratory Medicine and Thoracic Surgery
12 Ghent University Hospital
13 Department of Paediatric Respiratory Medicine
14 Airway Disease Section, National Heart and Lung Institute
15 Imperial College London
16 The Generation R Study group
17 Medstar Research Institute
18 The Wellcome Trust Centre for Human Genetics [Oxford]
19 ESPE Paris - Université Paris-Sorbonne - Paris 4 - École supérieure du professorat et de l'éducation - Académie de Paris
20 Population Genetics Laboratory [Tomsk, Russia]
21 USC - University of Southern California
22 Utrecht University [Utrecht]
23 Institute of Epidemiology
24 MRC IEU - MRC Integrative Epidemiology Unit [Bristol, Royaume-Uni]
25 Arizona Respiratory Center
26 Helsinki University Hospital
27 IRAS - Division of Occupational and Environmental Health, Institute for Risk Assessment
28 LMU - Ludwig Maximilian University [Munich]
29 National Institute of Health and Welfare
30 MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine
31 Erasmus MC - Erasmus University Medical Center [Rotterdam]
32 Department of Mathematics, University of Warwick
33 Sir Charles Gairdner Hospital
34 Swiss Tropical and Public Health Institute [Basel]
35 The Generation R Study; Pediatrics; Epidemiology
36 Uppsala University
37 Institute of Health Sciences and Biocenter Oulu
38 Tampere University Hospital
39 Institute of Biochemistry and Genetics of Ufa Scientific Centre
40 Pediatric Pulmonology, Allergology & Epidemiology
41 NCAR - National Center for Atmospheric Research [Boulder]
42 Epidemiology & Public Health
43 Department of Respiratory Medicine
44 Departments of Pulmonary Medicine and Medical Genetics
45 UQAC - Université du Québec à Chicoutimi
46 McGill University and Genome Quebec Innovation Centre
47 Department of Pediatric Pneumology and Immunology
48 MDC - Max Delbrück Center for Molecular Medicine [Berlin]
49 Faculty of Medicine and Life Sciences [Tampere]
50 LIPM - Laboratoire des interactions plantes micro-organismes
51 CAU - China Agricultural University
52 Harvard School of Public Health
53 Department of Epidemiology
54 National Institute for Environmental Health Sciences Research Triangle Park
55 NIMS - National Institute for Materials Science
56 Dept. of Epidemiology Research
57 Institute of Environmental Medicine [Stockholm, Sweden]
58 Center for Human Genomics
59 INSERM - Institut National de la Santé et de la Recherche Médicale
60 University of Tsukuba
61 Head of Medical Sequencing
62 Institute of environmental medicine
63 Respiratory Epidemiology and Public Health
64 CIRC - Centre International de Recherche contre le Cancer
65 Department of Chronic Disease Prevention
66 Aarhus University [Aarhus]
67 Institute of Metabolic Science
68 Section of Environment Occupation & Health
69 University of Manchester [Manchester]
70 Epidémiologie et Biostatistique
71 deCODE Genetics
72 Population Health Sciences and Education
73 Drug Safety Unit
74 Tohoku University [Sendai]
75 Department of Oceanography
76 UCSF - University of California [San Francisco]
77 Asthma and Allergy Department
78 IT University of Copenhagen
79 MRC Epidemiology Unit, Institute of Metabolic Science
80 Sachs’ Children and Youth Hospital [Stockholm, Sweden]
81 Genetic Epidemiology Unit
82 MRC Epidemiology Unit, Institute of Metabolic Science
83 UIC - University of Illinois [Chicago]
84 Titu Maiorescu University Bucharest
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Journal articles
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https://www.hal.inserm.fr/inserm-02874534
Contributor : Amaury Vaysse Connect in order to contact the contributor
Submitted on : Thursday, June 18, 2020 - 8:31:24 PM
Last modification on : Tuesday, October 19, 2021 - 2:18:09 PM

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INSERM | INRA | IFR69 | UNIV-EVRY | CNRS | INRAE | UNIV-PARIS7 | SU-LETTRES | SORBONNE-UNIVERSITE | USPC | UNIV-PARIS | SU-TI

Citation

Florence Demenais, Patricia Margaritte-Jeannin, Kathleen Barnes, William Cookson, Janine Altmüller, et al.. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nature Genetics, Nature Publishing Group, 2018, 50 (1), pp.42-53. ⟨10.1038/s41588-017-0014-7⟩. ⟨inserm-02874534⟩

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