Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8-T cells, J. Exp. Med, vol.186, pp.109-120, 1997. ,
,
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class Ispecific CD4+ and CD4-8-T cells in mice and humans, J. Exp. Med, vol.180, pp.1097-1106, 1994. ,
, CD1 recognition by mouse NK1+ T lymphocytes. Science, vol.268, pp.863-865, 1995.
Recognition of CD1d-restricted antigens by natural killer T cells, Nat. Rev. Immunol. 2012, vol.12, pp.845-857 ,
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides, Science, vol.278, pp.1626-1629, 1997. ,
Structural requirements for antigen presentation by mouse CD1, Proc Natl Acad Sci, vol.97, pp.10156-10161, 2000. ,
Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes, J. Immunol, vol.161, pp.3271-3281, 1998. ,
Alphagalactosylceramide (KRN7000) suppression of chemical-and oncogenedependent carcinogenesis, Proc Natl Acad Sci, vol.100, pp.9464-9469, 2003. ,
A brief review of clinical trials involving manipulation of invariant NKT cells as a promising approach in future cancer therapies. Cent, Eur. J. Immunol, vol.42, pp.181-195, 2017. ,
Novel approaches to exploiting invariant NKT cells in cancer immunotherapy, Front. Immunol, vol.9, p.384, 2018. ,
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining, J. Exp. Med, vol.195, pp.625-636, 2002. ,
The biology of NKT cells, Annu. Rev. Immunol, vol.25, pp.297-336, 2007. ,
Mouse CD1-autoreactive T cells have diverse patterns of reactivity to CD1+ targets, J. Immunol, vol.160, pp.3681-3688, 1998. ,
Tissue-specific recognition of mouse CD1 molecules, J. Immunol, vol.160, pp.3128-3134, 1998. ,
Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d, Nat. Immunol, vol.3, pp.55-60, 2002. ,
Unaltered phenotype, tissue distribution and function of Valpha14(+) NKT cells in germ-free mice, Eur. J. Immunol, vol.30, pp.620-625, 2000. ,
iNKT cell autoreactivity: what is 'self' and how is it recognized?, Nat. Rev. Immunol, vol.10, pp.272-277, 2010. ,
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection, J. Exp. Med, vol.208, pp.1163-1177, 2011. ,
Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation, Proc Natl Acad Sci, vol.104, pp.20490-20495, 2007. ,
A molecular basis for NKT cell recognition of CD1d-self-antigen, Immunity, vol.34, pp.315-326, 2011. ,
,
, PLoS Biol, vol.8, p.1000402, 2010.
Role of the MHC restriction during maturation of antigen-specific human T cells in the thymus, Eur. J. Immunol, vol.46, pp.560-569, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-02547732
Impact of TCR reactivity and HLA phenotype on naive CD8 T cell frequency in humans, J. Immunol, vol.184, pp.6731-6738, 2010. ,
Characterization of the human CD4(+) T-cell repertoire specific for major histocompatibility class Irestricted antigens, Eur. J. Immunol, vol.43, pp.3244-3253, 2013. ,
The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian alpha-linked glycosylceramides, Immunity, vol.41, pp.543-554, 2014. ,
Production and characterization of monoclonal antibodies against complexes of the NKT cell ligand alphagalactosylceramide bound to mouse CD1d, J. Immunol. Methods, vol.323, pp.11-23, 2007. ,
The SYK tyrosine kinase: a crucial player in diverse biological functions, Nat. Rev. Immunol, vol.10, pp.387-402, 2010. ,
Autoreactivity to sulfatide by human invariant NKT cells, J. Immunol, vol.199, pp.97-106, 2017. ,
Recognition of lyso-phospholipids by human natural killer T lymphocytes, PLoS Biol, vol.7, p.1000228, 2009. ,
Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor, EMBO J, vol.31, pp.2047-2059, 2012. ,
Structural basis for the recognition of C20:2-alphaGalCer by the invariant natural killer T cell receptor-like antibody L363, J. Biol. Chem, vol.287, pp.1269-1278, 2012. ,
?? T cell antigen receptor recognition of CD1a presenting self lipid ligands, Nat. Immunol, vol.16, pp.258-266, 2015. ,
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids, Nat. Immunol, vol.19, pp.397-406, 2018. ,
Lipids hide or step aside for CD1-autoreactive T cell receptors, Curr. Opin. Immunol, vol.52, pp.93-99, 2018. ,
Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression, J. Immunol, vol.163, pp.2610-2620, 1999. ,
Signal transduction by lymphocyte antigen receptors, Cell, vol.76, pp.263-274, 1994. ,
The Syk family of protein tyrosine kinases in T-cell activation and development, Immunol. Rev, vol.165, pp.167-180, 1998. ,
FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation ,
, J. Clin. Invest, vol.116, pp.2484-2492, 2006.
Lineage-specific analysis of Syk function in autoantibodyinduced arthritis, Front. Immunol, vol.9, p.555, 2018. ,
Whole-genome expression profiling in skin reveals SYK as a key regulator of inflammation in experimental epidermolysis bullosa acquisita, Front. Immunol, vol.9, p.249, 2018. ,
Fc epsilon receptor type I gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus, Arthritis Rheum, vol.44, pp.1114-1121, 2001. ,
TCR beta chain influences but does not solely control autoreactivity of V alpha 14J281T cells, J. Immunol, vol.167, pp.6239-6246, 2001. ,
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude, Immunity, vol.27, pp.203-213, 2007. ,
, Guidelines for the use of flow cytometry and cell sorting in immunological studies, vol.49, pp.1457-1973, 2019.
URL : https://hal.archives-ouvertes.fr/pasteur-01619848
, Abbreviations: ?GalCer: ?-GalactosylCeramide · iNKT: invariant natural killer T · SN: self-negative · SP: self-positive Full correspondence: Prof. Xavier Saulquin