Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche, Methods, vol.99, pp.62-68, 2016. ,
Concise reviews: Characteristics and potential applications of human dental tissue-derived mesenchymal stem cells, Stem Cells Dayt, vol.33, pp.627-638, 2015. ,
Mesenchymal stem cells: Molecular characteristics and clinical applications, World J. Stem Cells, vol.2, pp.67-80, 2010. ,
Concise Review: Mesenchymal Stromal Cells Anno 2019: Dawn of the Therapeutic Era?, Stem Cells Transl. Med, vol.8, pp.1126-1134, 2019. ,
The hidden treasure in apical papilla: The potential role in pulp/dentin regeneration and bioroot engineering, J. Endod, vol.34, pp.645-651, 2008. ,
Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: A pilot study, J. Endod, vol.34, pp.166-171, 2008. ,
Stem Cells of Dental Origin: Current Research Trends and Key Milestones towards Clinical Application, Stem Cells Int, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01454805
Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy, BioMed. Res. Int, p.6104738, 2019. ,
Stem Cells from the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration, Front. Bioeng. Biotechnol, vol.6, 2018. ,
The use of human dental pulp stem cells for in vivo bone tissue engineering: A systematic review, J. Tissue Eng, vol.9, 2018. ,
Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells, Biochem. Biophys. Res. Commun, vol.358, pp.948-953, 2007. ,
Hypoxia or in situ normoxia: The stem cell paradigm, J. Cell. Physiol, vol.219, pp.271-275, 2009. ,
Harnessing anaerobic nature of stem cells for use in regenerative medicine, Anaerobiosis and Stemness: An Evolutionary Paradigm, pp.258-286, 2016. ,
Priming Dental Pulp Stem Cells with Fibroblast Growth Factor-2 Increases Angiogenesis of Implanted Tissue-Engineered Constructs Through Hepatocyte Growth Factor and Vascular Endothelial Growth Factor Secretion, Stem Cells Transl. Med, vol.5, pp.392-404, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01622175
Analysis of the characteristics and expression profiles of coding and noncoding RNAs of human dental pulp stem cells in hypoxic conditions, Stem Cell Res. Ther, vol.10, 2019. ,
Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential, J. Cell Sci, vol.117, pp.2971-2981, 2004. ,
Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells, vol.39, pp.513-522, 2006. ,
Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells, Stem Cells Dev, vol.25, pp.848-860, 2016. ,
Cultivation of rat marrow-derived mesenchymal stem cells in reduced oxygen tension: Effects on in vitro and in vivo osteochondrogenesis, J. Cell. Physiol, vol.187, pp.345-355, 2001. ,
Proliferation and differentiation of bone marrow stromal cells under hypoxic conditions, Biochem. Biophys. Res. Commun, vol.347, pp.12-21, 2006. ,
In situ normoxia versus "Hypoxia, Anaerobiosis and Stemness: An Evolutionary Paradigm, pp.17-21, 2016. ,
Mesenchymal Stem/Stromal Cells in Regenerative Medicine: Can Preconditioning Strategies Improve Therapeutic Efficacy?, Transfus. Med. Hemother, vol.43, pp.256-267, 2016. ,
Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells, Biochem. Biophys. Res. Commun, vol.448, pp.218-224, 2014. ,
Prolonged exposure to hypoxic milieu improves the osteogenic potential of adipose derived stem cells, J. Cell. Biochem, vol.116, pp.1442-1453, 2015. ,
Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine, Int. J. Mol. Sci, 1195. ,
Autophagy in stem cells: Repair, remodelling and metabolic reprogramming, Dev. Camb. Engl, vol.145, 2018. ,
Regulation and role of autophagy in mammalian cells, Int. J. Biochem. Cell Biol, vol.36, pp.2445-2462, 2004. ,
Roles of autophagy in controlling stem cell identity: A perspective of self-renewal and differentiation, Cell Tissue Res, vol.374, pp.205-216, 2018. ,
Autophagy in stem cells, Autophagy, vol.9, pp.830-849, 2013. ,
LC3 conjugation system in mammalian autophagy, Int. J. Biochem. Cell Biol, vol.36, pp.2503-2518, 2004. ,
Mitochondrial autophagy: Life and breath of the cell, Autophagy, vol.4, pp.534-536, 2008. ,
Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX, Biochim. Biophys. Acta, vol.1853, pp.2775-2783, 2015. ,
BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells, Redox Biol, vol.13, pp.426-443, 2017. ,
Concentration-dependent effect of sodium hypochlorite on stem cells of apical papilla survival and differentiation, J. Endod, vol.40, pp.51-55, 2014. ,
In vitro assessment of a collagen/alginate composite scaffold for regenerative endodontics, Int. Endod. J, vol.50, pp.48-57, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02617452
Culture techniques and their applications to studies of vascular smooth muscle, Clin. Sci, vol.85, pp.501-513, 1993. ,
Population doubling: A simple and more accurate estimation of cell growth suppression in the in vitro assay for chromosomal aberrations that reduces irrelevant positive results, Environ. Mol. Mutagen, vol.43, pp.36-44, 2004. ,
Apoptosis and differentiation commitment: Novel insights revealed by gene profiling studies in mouse embryonic stem cells, Cell Death Differ, vol.13, pp.564-575, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00187902
Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia, PLoS ONE, vol.11, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-02870978
Quantitative three-dimensional evaluation of immunofluorescence staining for large whole mount spheroids with light sheet microscopy, Biomed. Opt. Express, vol.8, pp.484-499, 2017. ,
A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency, Stem Cell Res, vol.10, pp.118-131, 2013. ,
Comparing atmospheric and hypoxic cultured mesenchymal stem cell transcriptome: Implication for stem cell therapies targeting intervertebral discs, J. Transl. Med, vol.16, 2018. ,
Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells, Stem Cell Res. Ther, vol.9, 2018. ,
Comparison of stem cell behaviors between indigenous high and low-CD24 percentage expressing cells of stem cells from apical papilla (SCAPs), Tissue Cell, vol.48, pp.397-406, 2016. ,
Platelet-derived growth factor receptor beta identifies mesenchymal stem cells with enhanced engraftment to tissue injury and pro-angiogenic property, Cell. Mol. Life Sci, vol.75, pp.547-561, 2018. ,
Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens, Stem Cells, vol.20, pp.329-337, 2002. ,
CD49f enhances multipotency and maintains stemness through the direct regulation of OCT4 and SOX2, Stem Cells Dayt, vol.30, pp.876-887, 2012. ,
Single CD271 marker isolates mesenchymal stem cells from human dental pulp, Int. J. Oral Sci, vol.7, pp.205-212, 2015. ,
Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, vol.131, pp.861-872, 2007. ,
The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells, Stem Cell Rev, vol.12, pp.621-633, 2016. ,
Lancet Commission: Stem cells and regenerative medicine, Lancet, vol.391, pp.883-910, 2018. ,
The expansion of murine bone marrow cells preincubated in hypoxia as an in vitro indicator of their marrow-repopulating ability, Leukemia, vol.14, pp.735-739, 2000. ,
Combination of low O 2 concentration and mesenchymal stromal cells during culture of cord blood CD34(+) cells improves the maintenance and proliferative capacity of hematopoietic stem cells, J. Cell. Physiol, vol.227, pp.2750-2758, 2012. ,
Hypoxia preconditioned mesenchymal stem cells improve vascular and skeletal muscle fiber regeneration after ischemia through a Wnt4-dependent pathway, Mol. Ther. J. Am. Soc. Gene Ther, vol.18, pp.1545-1552, 2010. ,
URL : https://hal.archives-ouvertes.fr/inserm-00509086
Marrow-isolated adult multilineage inducible cells embedded within a biologically-inspired construct promote recovery in a mouse model of peripheral vascular disease, Biomed. Mater, vol.12, 2017. ,
Conditional ablation of integrin alpha-6 in mouse epidermis leads to skin fragility and inflammation, Eur. J. Cell Biol, vol.90, pp.270-277, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00532916
, , vol.66, pp.1748-1760, 2017.
Identification of biomarkers indicative of functional skeletal stem cells, Orthod. Craniofac. Res, vol.22, pp.192-198, 2019. ,
CD49f Acts as an Inflammation Sensor to Regulate Differentiation, Adhesion, and Migration of Human Mesenchymal Stem Cells, Stem Cells Dayt, vol.33, pp.2798-2810, 2015. ,
iPS cells: A game changer for future medicine, EMBO J, vol.33, pp.409-417, 2014. ,
Induction of pluripotent stem cells from fibroblast cultures, Nat. Protoc, vol.2, pp.3081-3089, 2007. ,
Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells, Tissue Eng. Part. C Methods, vol.19, pp.68-79, 2013. ,
Extracellular Vesicles: Evolving Factors in Stem Cell Biology, Stem Cells Int, 2016. ,
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1, Annu. Rev. Cell Dev. Biol, vol.15, pp.551-578, 1999. ,
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology, Annu. Rev. Pathol, vol.9, pp.47-71, 2014. ,
, Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation. Stem Cells Int, 2018.
Regulation of autophagy in mesenchymal stem cells modulates therapeutic effects on spinal cord injury, Brain Res, 2019. ,
BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming, Autophagy, vol.14, pp.915-917, 2017. ,
The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation, PLoS ONE, vol.13, 2018. ,
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