In situ printing of mesenchymal stromal cells, by laser-assisted bioprinting, for in vivo bone regeneration applications - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue Scientific Reports Année : 2017

In situ printing of mesenchymal stromal cells, by laser-assisted bioprinting, for in vivo bone regeneration applications

Résumé

Bioprinting has emerged as a novel technological approach with the potential to address unsolved questions in the field of tissue engineering. We have recently shown that Laser Assisted Bioprinting (LAB), due to its unprecedented cell printing resolution and precision, is an attractive tool for the in situ printing of a bone substitute. Here, we show that LAB can be used for the in situ printing of mesenchymal stromal cells, associated with collagen and nano-hydroxyapatite, in order to favor bone regeneration, in a calvaria defect model in mice. Also, by testing different cell printing geometries, we show that different cellular arrangements impact on bone tissue regeneration. This work opens new avenues on the development of novel strategies, using in situ bioprinting, for the building of tissues, from the ground up.
Fichier principal
Vignette du fichier
s41598-017-01914-x.pdf (2.95 Mo) Télécharger le fichier
Origine : Publication financée par une institution
Loading...

Dates et versions

inserm-02870621 , version 1 (16-06-2020)

Identifiants

Citer

Virginie Keriquel, Hugo Oliveira, Murielle Rémy, Sophia Ziane, Samantha Delmond, et al.. In situ printing of mesenchymal stromal cells, by laser-assisted bioprinting, for in vivo bone regeneration applications. Scientific Reports, 2017, 7 (1), pp.1778. ⟨10.1038/s41598-017-01914-x⟩. ⟨inserm-02870621⟩

Collections

INSERM BIOTIS
30 Consultations
53 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More