Skip to Main content Skip to Navigation
Journal articles

Self-control of vitamin K 2 production captured in the crystal EDITORS' PICK HIGHLIGHT Downloaded from

Abstract : Menaquinone (MK) or vitamin K2 is an important metabolite that controls the redox/energy status of Mycobacterium tuberculosis Although the major steps of MK biosynthesis have been delineated, the regulatory mechanisms of this pathway have not been adequately explored. Bashiri et al. now demonstrate that MenD, catalyzing the first committed step of MK production, is allosterically inhibited by a downstream cytosolic metabolite in the MK biosynthesis pathway.
Complete list of metadatas

Cited literature [11 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-02868898
Contributor : Laurent Kremer <>
Submitted on : Monday, June 15, 2020 - 4:42:00 PM
Last modification on : Tuesday, June 16, 2020 - 10:30:57 AM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

Blaise Mickaël, Laurent Kremer. Self-control of vitamin K 2 production captured in the crystal EDITORS' PICK HIGHLIGHT Downloaded from. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (12), pp.3771-3772. ⟨10.1074/jbc.H120.013113⟩. ⟨inserm-02868898⟩

Share

Metrics

Record views

1891