, , p.447
Distinct cell-and layer-specific expression patterns and 448 independent regulation of Kv2 channel subtypes in cortical pyramidal neurons, J 449 Neurosci, vol.35, pp.14922-14942, 2015. ,
, , p.451
Chronic loss of CA2 transmission leads to 452 hippocampal hyperexcitability, Neuron, vol.94, pp.642-655, 2017. ,
Potassium-induced epileptiform activity in area CA3 454 varies markedly along the septotemporal axis of the rat hippocampus, Brain Res, vol.455, pp.169-173, 1986. ,
Strong CA2 pyramidal neuron synapses define a powerful 457 disynaptic cortico-hippocampal loop, Neuron, vol.66, pp.560-572, 2010. ,
Frequency-dependent 459 regulation of rat hippocampal somato-dendritic excitability by the K+ channel subunit 460 Kv2.1, J Physiol, vol.522, pp.19-31, 2000. ,
Kv2 subunits underlie 462 slowly inactivating potassium current in rat neocortical pyramidal neurons, J Physiol, vol.463, pp.941-960, 2007. ,
The hippocampal CA2 region is essential for social memory, Nature, vol.465, pp.88-92, 2014. ,
Contrasting 467 immunohistochemical localizations in rat brain of two novel K+ channels of the Shab 468 subfamily, J Neurosci, vol.13, pp.1569-1576, 1993. ,
A hippocampal network 470 for spatial coding during immobility and sleep, Nature, vol.531, pp.185-190, 2016. ,
A unique ion channel clustering domain on the axon 472 initial segment of mammalian neurons, J Comp Neurol, vol.522, pp.2594-2608, 2014. ,
Distinct axo-somato-dendritic distributions 474 of three potassium channels in CA1 hippocampal pyramidal cells, Eur J Neurosci, vol.475, pp.1771-1783, 2014. ,
, , p.477
Cell type-specific genetic and optogenetic 478 tools reveal hippocampal CA2 circuits, Nat Neurosci, vol.17, pp.269-279, 2014. ,
AMIGO, a 480 transmembrane protein implicated in axon tract development, defines a novel protein 481 family with leucine-rich repeats, J Cell Biol, vol.160, pp.963-973, 2003. ,
, , p.483
Hepler 484 JR (2010) RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and 485 hippocampal-based learning and memory, Proc Natl Acad Sci U S A, vol.107, pp.16994-16998 ,
Defining a molecular atlas of the hippocampus using DNA 487 microarrays and high-throughput in situ hybridization, J Neurosci, vol.24, pp.3879-3889, 2004. ,
Redefining the boundaries of the 489 hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional 490 reconstruction, J Comp Neurol, vol.485, pp.1-10, 2005. ,
The hippocampal CA3 network: an in vivo 492 intracellular labeling study, J Comp Neurol, vol.339, pp.181-208, 1994. ,
,
Metadata matters: access to image data in the real world, J Cell Biol, vol.495, pp.777-782, 2010. ,
Kv2 channel regulation of action potential repolarization and firing 497 patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons, J Neurosci, vol.498, pp.4991-5002, 2014. ,
Studies on the structure of the cerebral cortex. II. Continuation of the 500 study of the ammonic system, J Psychol Neurol, vol.46, pp.113-177, 1934. ,
A synaptically controlled, associative signal for Hebbian plasticity 502 in hippocampal neurons, Science, vol.275, pp.209-213, 1997. ,
Differential spatiotemporal expression of K+ 504 channel polypeptides in rat hippocampal neurons developing in situ and in vitro, J 505 Neurosci, vol.15, pp.3840-3851, 1995. ,
, , p.507, 2014.
, Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K(+) 508 channels and ryanodine receptors, J Comp Neurol, vol.522, pp.3555-3574
Hippocampal CA2 activity 510 patterns change over time to a larger extent than between spatial contexts, Neuron, vol.511, pp.190-201, 2015. ,
Benefits and pitfalls of secondary antibodies: why 513 choosing the right secondary is of primary importance, PLoS One, vol.7, p.38313, 2012. ,
Identification of the Kv2.1 K+ channel as a major component 515 of the delayed rectifier K+ current in rat hippocampal neurons, J Neurosci, vol.19, pp.1728-1735, 1999. ,
Proximodistal 517 segregation of nonspatial information in CA3: preferential recruitment of a proximal CA3-518 distal CA1 network in nonspatial recognition memory, J Neurosci, vol.33, pp.11506-11514, 2013. ,
, , p.520
KChIPs and Kv4 alpha 521 subunits as integral components of A-type potassium channels in mammalian brain, J 522 Neurosci, vol.24, pp.7903-7915, 2004. ,
The Kv2.1 K+ channel targets to the axon initial 524 segment of hippocampal and cortical neurons in culture and in situ, BMC Neurosci, vol.9, p.112, 2008. ,
Reduction of lipofuscin-like autofluorescence 526 in fluorescently labeled tissue, J Histochem Cytochem, vol.47, pp.719-730, 1999. ,
Regional differences in hippocampal 528 calcium handling provide a cellular mechanism for limiting plasticity, Proc Natl Acad Sci, vol.529, pp.14080-14084, 2009. ,
, , p.531
, , p.532
Deletion of the Kv2.1 delayed rectifier potassium channel leads to 533 neuronal and behavioral hyperexcitability, Genes Brain Behav, vol.13, pp.394-408, 2014. ,
, , p.535, 2017.
, The dendrites of CA2 and CA1 pyramidal neurons differentially regulate information flow 536 in the cortico-hippocampal circuit, J Neurosci, vol.37, pp.3276-3293
Lesions to the CA2 region of the hippocampus impair social 538 memory in mice, Eur J Neurosci, vol.40, pp.3294-3301, 2014. ,
Dendritic Na+ spikes enable cortical input 540 to drive action potential output from hippocampal CA2 pyramidal neurons, vol.3, 2014. ,
CNS distribution of members of the 542 two-pore-domain (KCNK) potassium channel family, J Neurosci, vol.21, pp.7491-7505, 2001. ,
, , p.544
A novel epileptic 545 encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and 546 localization, J Gen Physiol, vol.146, pp.399-410, 2015. ,
, , p.548
, , p.549
Genomic anatomy of the hippocampus, Neuron, vol.60, pp.1010-1021, 2008. ,
, , p.551
De novo KCNB1 mutations in 552 epileptic encephalopathy, Ann Neurol, vol.76, pp.529-540, 2014. ,
Immunological identification and characterization of a delayed rectifier K+ 554 channel polypeptide in rat brain, Proc Natl Acad Sci U S A, vol.88, pp.10764-10768, 1991. ,
Modification of Kv2.1 K+ currents by the silent Kv10 subunits, 2004. ,
, Brain Res Mol Brain Res, vol.123, pp.91-103
Synaptic plasticity (and the lack thereof) in 558 hippocampal CA2 neurons, J Neurosci, vol.27, pp.12025-12032, 2007. ,