Journal articles

Progress update from the hippocampal subfields group

Rosanna K Olsen ^{1, 2} Valerie A Carr ³ Ana M Daugherty ⁴ Renaud La Joie ⁵ Robert S.C. Amaral ⁶ Katrin Amunts ⁷ Jean C Augustinack ⁸ Arnold Bakker ⁹ Andrew R Bender ¹⁰ David Berron ¹¹ Marina Boccardi ¹² Martina Bocchetta ¹³ Alison C Burggren ¹⁴ M. Mallar Mallar Chakravarty ¹⁵ Gaël Chételat ^{16, 17, 18} Robin Flores ^{16, 17} Jordan Dekraker ¹⁹ Song‐lin Ding ²⁰ Mirjam I Geerlings ²¹ yushan Huang ²² Ricardo Insausti ²³ Elliott G Johnson ²⁴ Prabesh Kanel ²⁵ Olga Kedo ²⁶ Kristen M Kennedy ²⁷ Attila Keresztes ²⁸ Joshua K Lee ²⁹ Ulman M Lindenberger ³⁰ Susanne Mueller ³¹ Elizabeth M Mulligan ³² Noa Ofen ^{4, 33} Daniela J Palombo ³⁴ Lorenzo Pasquini ³¹ John Pluta ³⁵ Naftali Raz ⁴ Karen M Rodrigue ²⁷ Margaret L Schlichting ² yee Lee Shing ^{28, 36} Craig E.L. Stark ³⁷ Trevor A Steve ²² Nanthia A Suthana ³⁸ Lei Wang ³⁹ Markus Werkle‐bergner ²⁸ Paul A. yushkevich ⁴⁰ Qijing yu ⁴ Laura E.M. Wisse ³⁵

1 RRI - Rotman Research Institute at the Baycrest Centre

2 University of Toronto

3 SJSU - San Jose State University [San José]

4 Wayne State University [Detroit]

5 Memory and Aging Center [San Francisco, CA, États-Unis]

6 Douglas Mental Health University Institute [Montréal]

7 INM-1 - Institute of Neuroscience and Medicine [Jülich]

8 Massachusetts General Hospital [Boston]

9 Johns Hopkins University School of Medicine [Baltimore]

10 Lund University [Lund]

11 DZNE - German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen

12 LENITEM - Neuroimaging and Telemedicine

13 DRC - Dementia Research Centre [London]

14 University of Oregon [Eugene]

15 McGill University = Université McGill [Montréal, Canada]

16 PhIND - Physiopathologie et imagerie des troubles neurologiques

17 Cyceron - GIP Cyceron

18 UNICAEN - Université de Caen Normandie

19 UWO - University of Western Ontario

20 Allen Institute for Brain Science [Seattle, WA, USA]

21 University Medical Center [Utrecht]

22 University of Alberta

23 School of Medicine - CRIB - Human Neuroanatomy Laboratory [Albacete, Spain]

24 University of California

25 University of Michigan Medical School [Ann Arbor]

26 Heinrich Heine Universität Düsseldorf = Heinrich Heine University [Düsseldorf]

27 UT Dallas - University of Texas at Dallas [Richardson]

28 Max Planck Institute for Human Development

29 UC Davis - University of California [Davis]

30 Freie Universität Berlin

31 UCSF - University of California [San Francisco]

32 FSU - Florida State University [Tallahassee]

33 Weizmann Institutes of Science [Rehovot, Israel]

34 UBC - University of British Columbia

35 University of Pennsylvania [Philadelphia]

36 Goethe-University Frankfurt am Main

37 UCI - University of California [Irvine]

38 UCLA - University of California [Los Angeles]

39 Northwestern University Feinberg School of Medicine

40 PICSL - Penn Image Computing & Science Lab [Philadelphia]

Abstract : Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippo-campal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods: Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.

Keywords : Human Volumetry Hippocampus Neuroimaging Structural imaging Neuroanatomy Histology Cytoarchitec- ture ex vivo

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Neurons and Cognition [q-bio.NC]

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https://www.hal.inserm.fr/inserm-02747115
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Submitted on : Wednesday, June 3, 2020 - 11:24:20 AM
Last modification on : Tuesday, May 3, 2022 - 3:14:04 PM
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