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The weekend effect in kidney transplantation outcomes: a French cohort‐based study

Abstract : Background: Numerous studies have reported a weekend effect on outcomes for diseases treated at hospitals. No study has been conducted in France for kidney transplantation. We therefore performed a cohort-based study to evaluate whether outcomes of kidney transplant recipients display a weekend effect. Methods: Data were extracted from the French DIVAT cohort. Patients aged 18 years and older, transplanted with a single kidney from deceased donors between 2005 and 2017 were studied. Linear regression, logistic regression and cause specific Cox model were used. Results: Among the 6652 studied patients, 4653 patients were transplanted during weekdays (69.9%) versus 1999 during weekends (30.1%). The only statistically significant difference was the percentage of patients with vascular surgical complication(s) at 30 days: 13.3% in the weekend group versus 16.2% in the weekday group 0.79 (95% CI: 0.68; 0.92). We did not observe other significant differences for the other outcomes: patient or graft survival, the risk of acute rejection episodes, the 30-day percentage of urological complications, and the 1-year estimated glomerular filtration rate. Conclusion: Our study highlights a small protective weekend effect with less post-surgery vascular complications compared to weekdays. This paradox might be explained by a different handling of weekend transplantations.
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https://www.hal.inserm.fr/inserm-02626392
Contributor : Christine Dupuis <>
Submitted on : Tuesday, May 26, 2020 - 5:16:19 PM
Last modification on : Wednesday, August 19, 2020 - 11:19:04 AM

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Simon Ville, Julien Branchereau, Adeline Cornuaud, Jacques Dantal, Christophe Legendre, et al.. The weekend effect in kidney transplantation outcomes: a French cohort‐based study. Transplant International, Wiley, 2020, Online ahead of print. ⟨10.1111/tri.13653⟩. ⟨inserm-02626392⟩

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