When physics takes over: BAR proteins and membrane curvature, Trends Cell Biol, vol.25, pp.780-792, 2015. ,
Endophilin marks and controls a clathrin-independent endocytic pathway, Nature, vol.517, pp.460-465, 2015. ,
FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis, Nat. Cell Biol, vol.20, pp.1023-1031, 2018. ,
Endophilin-A2 functions in membrane scission in clathrinindependent endocytosis, Nature, vol.517, pp.493-496, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01219767
Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCAM)-ALCAM interaction, J. Biol. Chem, vol.276, pp.25783-25790, 2001. ,
Activated leukocyte cell adhesion molecule is a component of the endothelial junction involved in transendothelial monocyte migration, FEBS Lett, vol.580, pp.2637-2645, 2006. ,
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system, Nat. Immunol, vol.9, pp.137-145, 2008. ,
Relevance of CD6-mediated interactions in T cell activation and proliferation, J. Immunol, vol.173, pp.2262-2270, 2004. ,
Frontline: optimal T cell activation requires the engagement of CD6 and CD166, Eur. J. Immunol, vol.34, pp.930-940, 2004. ,
Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells, Blood, vol.107, pp.3212-3220, 2006. ,
Cytoplasmic overexpression of ALCAM is prognostic of disease progression in breast cancer, J. Clin. Pathol, vol.59, pp.403-409, 2006. ,
The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy, J. Thorac. Oncol, vol.7, pp.1880-1890, 2012. ,
ALCAM/CD166: cancer-related issues, Cancer Genomics Proteom, vol.7, pp.231-243, 2010. ,
Increased expression of stem cell markers in malignant melanoma, Mod. Pathol, vol.20, pp.102-107, 2007. ,
Subcellular localization of activated leukocyte cell adhesion molecule is a molecular predictor of survival in ovarian carcinoma patients, Clin. Cancer Res, vol.14, pp.1726-1733, 2008. ,
ALCAM/ CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival, J. Clin. Pathol, vol.57, pp.1160-1164, 2004. ,
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis, Cell, vol.148, pp.259-272, 2012. ,
CD166-mediated epidermal growth factor receptor phosphorylation promotes the growth of oral squamous cell carcinoma, Oral. Oncol, vol.59, pp.1-11, 2016. ,
Recombinant full-length human IgG1s targeting hormonerefractory prostate cancer, J. Mol. Med, vol.85, pp.1113-1123, 2007. ,
Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody, J. Cell Sci, vol.118, pp.1515-1525, 2005. ,
Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells, Mol. Cancer Ther, vol.6, pp.2737-2746, 2007. ,
Cell adhesion molecule CD166 drives malignant progression and osteolytic disease in multiple myeloma, Cancer Res, vol.76, pp.6901-6910, 2016. ,
Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis, PLoS Biol, vol.12, p.1001832, 2014. ,
Sorting of clathrin-independent cargo proteins depends on Rab35 delivered by clathrin-mediated endocytosis, Traffic, vol.16, pp.994-1009, 2015. ,
GRAF1-dependent endocytosis, Biochem. Soc. Trans, vol.37, pp.1061-1065, 2009. ,
The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway, Curr. Biol, vol.18, pp.1802-1808, 2008. ,
Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis, Nat. Commun, vol.9, p.1835, 2018. ,
Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton, J. Biol. Chem, vol.289, pp.13445-13460, 2014. ,
Friction mediates scission of tubular membranes scaffolded by BAR proteins, Cell, vol.170, p.111, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01559973
Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8, FASEB J, vol.25, pp.242-254, 2011. ,
Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells, Biochim. Biophys. Acta, vol.1860, pp.2255-2268, 2016. ,
Glycolipids and lectins in endocytic uptake processes, J. Mol. Biol, vol.428, pp.4792-4818, 2016. ,
Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers, Nat. Cell Biol, vol.16, pp.595-606, 2014. ,
A glucosylceramide synthase inhibitor protects rats against the cytotoxic effects of shiga toxin 2, Pediatr. Res, vol.69, pp.390-394, 2011. ,
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes, Diabetes, vol.56, pp.1210-1218, 2007. ,
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells, J. Cell Biol, vol.190, pp.675-691, 2010. ,
Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium, Clin. Cancer Res, vol.17, pp.7035-7046, 2011. ,
Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke, Sci. Rep, vol.7, p.40994, 2017. ,
CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells, PLoS ONE, vol.9, p.107247, 2014. ,
Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes, Neuropathol. Appl. Neurobiol, vol.38, pp.201-212, 2012. ,
Metastasis-associated gene expression changes predict poor outcomes in patients with dukes stage B and C colorectal cancer, Clin. Cancer Res, vol.15, pp.7642-7651, 2009. ,
EphA3 promotes malignant transformation of colorectal epithelial cells by upregulating oncogenic pathways, Cancer Lett, vol.383, pp.195-203, 2016. ,
Competition between TIAM1 and membranes balances endophilin A3 activity in cancer metastasis, Dev. Cell, vol.45, pp.738-752, 2018. ,
Quantitative methods for analyzing cell-cell adhesion in development, Dev. Biol, vol.401, pp.165-174, 2015. ,
Cadherin-11 localizes to focal adhesions and promotes cellsubstrate adhesion, Nat. Commun, vol.7, p.10909, 2016. ,
Shiga toxin-A model for glycolipid-dependent and lectin-driven endocytosis, Toxins, 2017. ,
High frequency of autologous anti-melanoma CTL directed against an antigen generated by a point mutation in a new helicase gene, J. Immunol, vol.164, pp.6057-6066, 2000. ,
Production of stable cytolytic T-cell clones directed against autologous human melanoma, Int J. Cancer, vol.39, pp.390-396, 1987. ,
Shiga toxin B-subunit as a tool to study retrograde transport, Methods Mol. Med, vol.73, pp.209-220, 2003. ,
Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution, Science, vol.346, p.1257998, 2014. ,
Membrane dynamics of dividing cells imaged by lattice lightsheet microscopy, Mol. Biol. Cell, vol.27, pp.3418-3435, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02338290
Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria, Dev. Cell, vol.18, pp.324-331, 2010. ,
, the Walloon Region, Belgium. The LLSM was financed by PIA France-Bioimaging (ANR-10-INBS-04_01)
are supported by PhD fellowships from FRIA/FNRS (Belgium). C.L.G. is an EMBO Long-term postdoctoral fellow. P.V.D.B. and D.A. are supported by WELBIO (Fédération Wallonie-Bruxelles, Belgium), We greatly acknowledge the Cell and Tissue Imaging Facility (PICT-IBiSA) and Nikon Imaging Centre, Institut Curie, member of the French National Research Infrastructure France-BioImaging (ANR-10-INBS-04). H.-F.R. is a FNRS postdoctoral research fellow (Belgium) ,