Pathogenesis of pulmonary arterial hypertension: lessons from cancer, Eur Respir Rev, vol.22, pp.543-551, 2013. ,
The cancer theory of pulmonary arterial hypertension, Pulm Circ, vol.7, pp.285-299, 2017. ,
The cancer paradigm of severe pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.178, pp.558-564, 2008. ,
Molecular pathogenesis and current pathology of pulmonary hypertension, Heart Fail Rev, vol.21, pp.239-257, 2016. ,
Pulmonary arterial hypertension: pathogenesis and clinical management, BMJ, vol.360, 2018. ,
Molecular mechanisms of pulmonary vascular remodeling in pulmonary arterial hypertension, Int J Mol Sci, vol.17, p.761, 2016. ,
The hallmarks of cancer, Cell, vol.100, pp.57-70, 2000. ,
Hallmarks of cancer: the next generation, Cell, vol.144, pp.646-674, 2011. ,
Translational advances in the field of pulmonary hypertension. From cancer biology to new pulmonary arterial hypertension therapeutics. Targeting cell growth and proliferation signaling hubs, Am J Respir Crit Care Med, vol.195, pp.425-437, 2017. ,
Hallmarks of cancer: the next generation, Cell, vol.144, pp.646-674, 2011. ,
Primary pulmonary hypertension between inflammation and cancer, Chest, vol.114, pp.225-230, 1998. ,
Reversal of experimental pulmonary hypertension by PDGF inhibition, J Clin Inves, vol.115, pp.2811-2821, 2005. ,
Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis, J Pathol, vol.195, pp.367-374, 2001. ,
mTORC2 coordinates pulmonary artery smooth muscle cell metabolism, proliferation and survival in pulmonary arterial hypertension, Circulation, vol.129, pp.864-874, 2014. ,
Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension, Am J Physiol Heart Circ Physiol, vol.298, pp.1235-1248, 2010. ,
A novel p38 mitogenactivated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension, J Biol Chem, vol.288, pp.25701-25716, 2013. ,
Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells, Am J Physiol Lung Cell Mol Physiol, vol.310, pp.187-201, 2016. ,
Hyperplastic growth of pulmonary artery smooth muscle cells from subjects with pulmonary arterial hypertension is activated through JNK and p38 MAPK, PLoS One, vol.10, p.123662, 2015. ,
HIPPOintegrin linked kinase crosstalk controls self-sustaining proliferation and survival in pulmonary hypertension, Am J Respir Crit Care Med, vol.194, pp.866-877, 2016. ,
Matrix remodeling promotes pulmonary hypertension through feedback mechanoactivation of the YAP/TAZ-miR-130/301 circuit, Cell Rep, vol.13, pp.1016-1032, 2015. ,
Endothelial and smooth muscle cell interaction via FoxM1 signaling mediates vascular remodeling and pulmonary hypertension, Am J Respir Crit Care Med, vol.198, pp.788-802, 2018. ,
Adventitial fibroblasts induce a distinct pro-inflammatory/pro-fibrotic macrophage phenotype in pulmonary hypertension, J Immunol, vol.193, pp.597-609, 2014. ,
Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension, Nat Med, vol.20, pp.1289-1300, 2014. ,
Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth, Circ Res, vol.92, pp.1162-1169, 2003. ,
Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension, J Am Heart Assoc, vol.2, p.188, 2013. ,
Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1{alpha}, Circ Res, vol.102, pp.1036-1045, 2008. ,
DNA microarray and signal transduction analysis in pulmonary artery smooth muscle cells from heritable and idiopathic pulmonary arterial hypertension subjects, J Cell Biochem, vol.116, pp.386-397, 2015. ,
Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension, Circulation, vol.127, pp.1664-1676, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00829264
Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis, Circ Res, vol.88, pp.555-562, 2001. ,
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension, Circulation, vol.123, pp.1205-1215, 2011. ,
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension, J Clin Invest, vol.115, pp.1479-1491, 2005. ,
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension, Am J Physiol Lung Cell Mol Physiol, vol.308, pp.208-220, 2015. ,
Hallmarks of pulmonary hypertension: mesenchymal and inflammatory cell metabolic reprogramming, Antiox Redox Signal, vol.28, pp.230-250, 2018. ,
The metabolic basis of pulmonary arterial hypertension, Cell Metab, vol.19, pp.558-573, 2014. ,
Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice, Eur Respir Rev, vol.26, 2017. ,
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension, Pulm Circ, vol.3, pp.144-152, 2013. ,
Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension, Am J Physiol Lung Cell Mol Physiol, vol.293, pp.548-554, 2007. ,
Hypoxia inducible-factor1a regulates the metabolic shift of pulmonary hypertensive endothelial cells, Am J Pathol, vol.176, pp.1130-1138, 2010. ,
Metabolic and proliferative state of vascular adventitial fibroblasts in pulmonary hypertension is regulated through a microRNA-124/PTBP1 (polypyrimidine tract binding protein 1)/pyruvate kinase muscle axis, Circulation, vol.136, pp.2468-2485, 2017. ,
Mitochondrial dynamics in pulmonary arterial hypertension, J Mol Med (Berl), vol.93, pp.229-242, 2015. ,
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension, J Clin Invest, vol.126, pp.3313-3335, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02479282
Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension, Sci Transl Med, vol.2, pp.44-58, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02476445
Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension, J Clin Invest, vol.101, pp.927-934, 1998. ,
Role for telomerase in pulmonary hypertension, Circulation, vol.131, pp.742-755, 2015. ,
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension, Circ Res, vol.115, pp.165-175, 2014. ,
Dominant role for regulatory T cells in protecting females against pulmonary hypertension, Circ Res, vol.122, pp.1689-1702, 2018. ,
The roles of immunity in the prevention and evolution of pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.195, pp.1292-1299, 2017. ,
Immune cells and autoantibodies in pulmonary arterial hypertension, Acta Biochim Biophys Sin, vol.49, pp.1047-1057, 2017. ,
Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.186, pp.897-908, 2012. ,
Genetics and genomics of pulmonary arterial hypertension, J Am Coll Cardiol, vol.62, pp.13-21, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02137830
Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension, Circ Res, vol.88, pp.2-11, 2001. ,
Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.182, pp.1153-1160, 2010. ,
Endothelial chromosome 13 deletion in congenital heart disease-associated pulmonary arterial hypertension dysregulates SMAD9 signaling, Am J Respir Crit Care Med, vol.191, pp.850-854, 2015. ,
Role for DNA damage signaling in pulmonary arterial hypertension, Circulation, vol.129, pp.786-797, 2014. ,
Wholeexome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.189, pp.1260-1272, 2014. ,
DNA damage and pulmonary hypertension, Int J Mol Sci, vol.17, p.990, 2016. ,
Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity, Am J Respir Crit Care Med, vol.195, pp.930-941, 2017. ,
Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers, Cell Stem Cell, vol.20, pp.490-504, 2017. ,
A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents, Am J Respir Crit Care Med, vol.186, pp.666-676, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-00905191
Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension, Am J Respir Cell Mol Biol, vol.45, pp.311-322, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00579959
HIPPO-Integrin-linked kinase cross-talk controls self-sustaining proliferation and survival in pulmonary hypertension, Am J Respir Crit Care Med, vol.194, pp.866-877, 2016. ,
Metabolic and proliferative state of vascular adventitial fibroblasts in pulmonary hypertension is regulated through a microRNA-124/PTBP1 (polypyrimidine tract binding protein 1)/pyruvate kinase muscle axis, Circulation, vol.136, pp.2468-2485, 2017. ,
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents, J Clin Invest, vol.119, pp.512-523, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00499635
Expression of vascular endothelial growth factor and its receptors correlates closely with formation of the plexiform lesion in human pulmonary hypertension, Pathol Int, vol.50, pp.472-479, 2000. ,
iPSC model of pulmonary arterial hypertension reveals novel gene expression and patient specificity, Am J Respir Crit Care Med, 2016. ,
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension, Circulation, vol.129, pp.1586-1597, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-02578269
Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis, Am J Pathol, vol.185, pp.69-84, 2015. ,
Bone marrow-derived cells contribute to the pathogenesis of pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.193, pp.898-909, 2016. ,
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension, Nat Commun, vol.9, p.1416, 2018. ,
New molecular targets of pulmonary vascular remodeling in pulmonary arterial hypertension: importance of endothelial communication, Chest, vol.147, pp.529-537, 2015. ,
Pathogenesis of pulmonary arterial hypertension: lessons from cancer, Eur Respir Rev, vol.22, pp.543-551, 2013. ,
, Humbert M. Impression, sunset. Circulation, vol.127, pp.1098-1100, 2013.
Cardiovascular toxic effects of targeted cancer therapies, N Engl J Med, vol.375, pp.1457-1467, 2016. ,
The adventitia: essential regulator of vascular wall structure and function, Annu Rev Physiol, vol.75, pp.23-47, 2013. ,
The adventitia: a dynamic interface containing resident progenitor cells, Arterioscler Thromb Vasc Biol, vol.31, pp.1530-1539, 2011. ,
Nox and inflammation in the vascular adventitia, Hypertension, vol.67, pp.14-19, 2016. ,
Stromal cells in chronic inflammation and tertiary lymphoid organ formation, Annu Rev Immunol, vol.33, pp.715-745, 2015. ,
Fanning the flames: inflammation in cardiovascular diseases, Cardiovasc Res, vol.107, pp.307-309, 2015. ,
Inflammation and immunity in diseases of the arterial tree: players and layers, Circ Res, vol.116, pp.307-311, 2015. ,
The role of the adventitia in vascular inflammation, Cardiovasc Res, vol.75, pp.640-648, 2007. ,
Adventitial activation in the pathogenesis of injury-induced arterial remodeling: potential implications in transplant vasculopathy, Am J Pathol, vol.188, pp.838-845, 2018. ,
Stromal fibroblasts in cancer initiation and progression, Nature, vol.432, pp.332-337, 2004. ,
Differential effect of experimental hypertension and hypercholesterolemia on adventitial remodeling, Arterioscler Thromb Vasc Biol, vol.25, pp.447-453, 2005. ,
Adventitial macrophage and lymphocyte accumulation accompanying early stages of human coronary atherogenesis, Cardiovasc Pathol, vol.23, pp.193-197, 2014. ,
Varicella zoster virus vasculopathy: analysis of virus-infected arteries, Neurology, vol.77, pp.364-370, 2011. ,
Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries, Circulation, vol.93, pp.2178-2187, 1996. ,
Adventitial remodeling after coronary arterial injury, Circulation, vol.93, pp.340-348, 1996. ,
Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries, Circulation, vol.101, pp.1362-1365, 2000. ,
Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries, Am J Respir Cell Mol Biol, vol.16, pp.366-371, 1997. ,
Hypoxia and incorporation of 3H-thymidine by cells of the rat pulmonary arteries and alveolar wall, Am J Pathol, vol.96, pp.51-70, 1979. ,
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors, FASEB J, vol.16, pp.1660-1661, 2002. ,
Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension, J Immunol, vol.193, pp.597-609, 2014. ,
Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension, J Physiol, vol.597, pp.1103-1119, 2018. ,
MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts, Circ Res, vol.114, pp.67-78, 2014. ,
Inflammatory and immune responses in the arterial media, Circ Res, vol.116, pp.312-322, 2015. ,
Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.186, pp.897-908, 2012. ,
Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1, Am J Pathol, vol.168, pp.1793-1807, 2006. ,
C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.184, pp.116-123, 2011. ,
Neovascularization of the atherosclerotic plaque: interplay between atherosclerotic lesion, adventitia-derived microvessels and perivascular fat, Curr Opin Lipidol, vol.26, pp.405-411, 2015. ,
Adventitial angiogenesis early after coronary angioplasty: correlation with arterial remodeling, Arterioscler Thromb Vasc Biol, vol.19, pp.229-238, 1999. ,
Microvascular disease in chronic thromboembolic pulmonary hypertension: a role for pulmonary veins and systemic vasculature, Eur Respir J, vol.44, pp.1275-1288, 2014. ,
Intrapulmonary bronchopulmonary anastomoses and plexiform lesions in idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.193, pp.574-576, 2016. ,
Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.185, pp.311-321, 2012. ,
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension, Circulation, vol.136, pp.1920-1935, 2017. ,
Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension, J Immunol, vol.187, pp.2711-2722, 2011. ,
Modern age pathology of pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.186, pp.261-272, 2012. ,
The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension, Eur Respir J, vol.51, 2018. ,
Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients, Am J Physiol Lung Cell Mol Physiol, vol.308, pp.1002-1013, 2015. ,
Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension, Am J Respir Crit Care Med, vol.190, pp.98-111, 2014. ,
Resident cell lineages are preserved in pulmonary vascular remodeling, J Pathol, vol.244, pp.485-498, 2018. ,
The effect of continued hypoxia on rat pulmonary arterial circulation. An ultrastructural study, Lab Invest, vol.38, pp.188-200, 1978. ,
Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension, Am J Physiol, vol.255, pp.1484-1491, 1988. ,
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension, FASEB J, vol.15, pp.427-438, 2001. ,
Reversal of experimental pulmonary hypertension by PDGF inhibition, J Clin Invest, vol.115, pp.2811-2821, 2005. ,
Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent, Int J Biochem Cell Biol, vol.54, pp.137-148, 2014. ,
Management of pulmonary arterial hypertension, J Am Coll Cardiol, vol.65, pp.1976-1997, 2015. ,
Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization, Am J Physiol Lung Cell Mol Physiol, vol.297, pp.1082-1090, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00499633
Physiologic and molecular consequences of endothelial Bmpr2 mutation, Respir Res, vol.12, p.84, 2011. ,
Prolyl-4 hydroxylase 2 (PHD2) deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in mice and humans through hypoxia-inducible factor-2alpha, Circulation, vol.133, pp.2447-2458, 2016. ,
Cell autonomous and non-cell autonomous regulation of SMC progenitors in pulmonary hypertension, Cell Rep, vol.23, pp.1152-1165, 2018. ,
Recapitulation of developing artery muscularization in pulmonary hypertension, Cell Rep, vol.6, pp.809-817, 2014. ,
Endothelial and smooth muscle cell interaction via FoxM1 signaling mediates vascular remodeling and pulmonary hypertension, Am J Respir Crit Care Med, vol.198, pp.788-802, 2018. ,
Hypoxia-inducible factor-1alpha in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation, Circ Res, vol.112, pp.1230-1233, 2013. ,
An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension, J Clin Invest, vol.118, pp.1846-1857, 2008. ,
Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.190, pp.318-328, 2014. ,
Prevalence and impact of coronary artery disease in patients with pulmonary arterial hypertension, Am J Cardiol, vol.108, pp.460-464, 2011. ,
Implication of inflammation and epigenetic readers in coronary artery remodeling in patients with pulmonary arterial hypertension, Arterioscler Thromb Vasc Biol, vol.37, pp.1513-1523, 2017. ,
Kidney dysfunction in patients with pulmonary arterial hypertension, Pulm Circ, vol.7, pp.38-54, 2017. ,
Bone marrow transplantation prevents right ventricle disease in the caveolin-1-deficient mouse model of pulmonary hypertension, Blood Adv, vol.1, pp.526-534, 2017. ,
Abnormalities in the regulators of angiogenesis in patients with scleroderma, J Rheumatol, vol.36, pp.576-582, 2009. ,
Schistosomiasis and the pulmonary vasculature, Pulm Circ, vol.4, pp.353-362, 2013. ,
BMPR2 mutation status influences bronchial vascular changes in pulmonary arterial hypertension, Eur Respir J, vol.48, pp.1668-1681, 2016. ,
Insulin resistance in pulmonary arterial hypertension, Eur Respir J, vol.33, pp.318-324, 2009. ,
Metabolic dysfunction in pulmonary arterial hypertension, Curr Hypertens Rep, vol.17, p.20, 2015. ,
Plexogenic pulmonary hypertension associated with POEMS syndrome, Respir Med Case Rep, vol.22, pp.168-170, 2017. ,
Pulmonary tumor thrombotic microangiopathy induced by gastric carcinoma: morphometric and immunohistochemical analysis of six autopsy cases, Diagn Pathol, vol.6, p.27, 2011. ,
Presence of kidney disease as an outcome predictor in patients with pulmonary arterial hypertension, Am J Nephrol, vol.47, pp.134-143, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02003933
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension, J Mol Med, vol.93, pp.573-584, 2015. ,
In: Pulmonary hypertension: the present and future. Editor Malley J. Shelton CN: People's Medical Publishing House-USA, pp.1-9, 2011. ,
Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension, Eur Respir J, vol.29, pp.462-468, 2007. ,
Anti-endothelial cell antibodies in idiopathic and systemic sclerosis associated pulmonary arterial hypertension, Thorax, vol.60, pp.765-772, 2005. ,
Functional implications of IgG anti-endothelial cell antibodies in pulmonary arterial hypertension, Autoimmunity, vol.46, pp.463-470, 2013. ,
The enigma of pulmonary hypertension after splenectomy-does the megakaryocyte provide a clue?, QJM, vol.102, pp.743-745, 2009. ,
Adipose tissue as an immunological organ, Obesity (Silver Spring), vol.23, pp.512-518, 2015. ,
Relevant issues in the pathology and pathobiology of pulmonary hypertension, J Am Coll Cardiol, vol.62, pp.4-12, 2013. ,
In: Pulmonary hypertension: the present and future, pp.11-17, 2011. ,
Mitochondrial HSP90 accumulation promotes vascular remodeling in pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.198, pp.90-103, 2018. ,
Role of the aryl hydrocarbon receptor in sugen 5416-induced experimental pulmonary hypertension, Am J Respir Cell Mol Biol, vol.58, pp.320-330, 2018. ,
Hypoxia and pulmonary vascular endothelium, Ciba Found Symp, vol.78, pp.37-60, 1980. ,
The hyperproliferative endothelial cell phenotype in idiopathic pulmonary arterial hypertension, Am J Physiol Lung Cell Mol Physiol, vol.293, pp.546-547, 2007. ,
Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension, Circ Res, vol.88, pp.2-11, 2001. ,
Pathobiology of pulmonary arterial hypertension and right ventricular failure, Eur Respir J, vol.40, pp.1555-1565, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-02612634
Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.191, pp.208-218, 2015. ,
The role of vascular endothelial growth factor in pulmonary arterial hypertension. The angiogenesis paradox, Am J Respir Cell Mol Biol, vol.51, pp.474-484, 2014. ,
Vascular endothelial growth factor in the lung, Am J Physiol Lung Cell Mol Physiol, vol.290, pp.209-221, 2006. ,
The roles of immunity in the prevention and evolution of pulmonary arterial hypertension, Am J Respir Crit Care Med, vol.195, pp.1292-1299, 2017. ,
Abnormal glucose metabolism and high-energy expenditure in idiopathic pulmonary arterial hypertension, vol.14, pp.190-199, 2017. ,
The role of hyperglycemia and insulin resistance in the development and progression of pulmonary arterial hypertension, J Diabetes Res, p.2481659, 2016. ,
Severe pulmonary hypertension in postmenopausal obese women, Eur J Med Res, vol.11, pp.198-202, 2006. ,
Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure, Circulation, vol.120, pp.1951-1960, 2009. ,
Downregulation of MicroRNA-126 contributes to the failing right ventricle in pulmonary arterial hypertension, Circulation, vol.132, pp.932-943, 2015. ,
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload, Nature, vol.446, pp.444-448, 2007. ,
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension, Am J Respir Cell Mol Biol, vol.45, pp.1239-1247, 2011. ,
Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension, Eur J Pharmacol, vol.549, pp.107-116, 2006. ,
Right ventricle vasculature in human pulmonary hypertension assessed by stereology, Am J Respir Crit Care Med, vol.196, pp.1075-1077, 2017. ,
Vascular adaptation of the right ventricle in experimental pulmonary hypertension, Am J Respir Cell Mol Biol, vol.59, pp.479-489, 2018. ,
Right ventricular angiogenesis is an early adaptive response to chronic hypoxiainduced pulmonary hypertension, Microcirculation, vol.22, pp.724-736, 2015. ,