Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension - Archive ouverte HAL Access content directly
Journal Articles Journal of Clinical Investigation Year : 2018

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

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Yuichi Tamura
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Carole Phan
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Ly Tu
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Morane Le Hiress
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Raphaël Thuillet
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Etienne-Marie Jutant
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Elie Fadel
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Laurent Savale
  • Function : Author
  • PersonId : 944440
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Alice Huertas
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Marc Humbert
  • Function : Author
  • PersonId : 998406
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
Christophe Guignabert
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique
CV

Domains

Life Sciences [q-bio] Cellular Biology Life Sciences [q-bio] Life Sciences [q-bio] Human health and pathology Cardiology and cardiovascular system Life Sciences [q-bio] Human health and pathology Pulmonology and respiratory tract

Christophe Guignabert  : Connect in order to contact the contributor

https://www.hal.inserm.fr/inserm-02580448

Submitted on : Thursday, May 14, 2020-8:25:10 PM

Last modification on : Thursday, April 28, 2022-2:18:02 PM

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inserm-02580448 , version 1 (14-05-2020)

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Yuichi Tamura, Carole Phan, Ly Tu, Morane Le Hiress, Raphaël Thuillet, et al.. Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension. Journal of Clinical Investigation, 2018, 128 (5), pp.1956-1970. ⟨10.1172/JCI96462⟩. ⟨inserm-02580448⟩

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