Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension - Archive ouverte HAL Access content directly
Journal Articles Journal of Medicinal Chemistry Year : 2018

Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension

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Morane Le Hiress
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Bernardin Akagah
  • Function : Author
MIFCARE , 24 rue du Faubourg Saint-Jacques , 75014 Paris , France.
Guillaume Bernadat
  • Function : Author
Équipe “Molécules Fluorées et Chimie Médicinale” BioCIS
Ly Tu
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Raphaël Thuillet
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Alice Huertas
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Carole Phan
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Elie Fadel
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Gerald Simonneau
  • Function : Author
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Marc Humbert
  • Function : Author
  • PersonId : 998406
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Gael Jalce
  • Function : Author
MIFCARE , 24 rue du Faubourg Saint-Jacques , 75014 Paris , France.
Christophe Guignabert
Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
CV

Domains

Life Sciences [q-bio] Cellular Biology Life Sciences [q-bio] Life Sciences [q-bio] Human health and pathology Cardiology and cardiovascular system Life Sciences [q-bio] Human health and pathology Pulmonology and respiratory tract

Christophe Guignabert  : Connect in order to contact the contributor

https://www.hal.inserm.fr/inserm-02580381

Submitted on : Thursday, May 14, 2020-8:22:08 PM

Last modification on : Thursday, August 4, 2022-10:09:01 AM

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inserm-02580381 , version 1 (14-05-2020)

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Morane Le Hiress, Bernardin Akagah, Guillaume Bernadat, Ly Tu, Raphaël Thuillet, et al.. Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension. Journal of Medicinal Chemistry, 2018, 61 (7), pp.2725-2736. ⟨10.1021/acs.jmedchem.7b01312⟩. ⟨inserm-02580381⟩

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