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Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension

Morane Le Hiress 1, 2, 3 Bernardin Akagah 4 Guillaume Bernadat 5 Ly Tu 1, 2, 3 Raphaël Thuillet 1, 2, 3 Alice Huertas 1, 2, 3 Carole Phan 1, 2, 3 Elie Fadel 1, 2, 3 Gerald Simonneau 1, 2, 3 Marc Humbert 1, 2, 3 Gael Jalce 4 Christophe Guignabert 1, 2, 3 
1 Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France
2 INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France
3 AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
4 MIFCARE , 24 rue du Faubourg Saint-Jacques , 75014 Paris , France.
5 Équipe “Molécules Fluorées et Chimie Médicinale” BioCIS
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https://www.hal.inserm.fr/inserm-02580381
Contributor : Christophe Guignabert Connect in order to contact the contributor
Submitted on : Thursday, May 14, 2020 - 8:22:08 PM
Last modification on : Saturday, February 26, 2022 - 8:30:04 AM

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Morane Le Hiress, Bernardin Akagah, Guillaume Bernadat, Ly Tu, Raphaël Thuillet, et al.. Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension. Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (7), pp.2725-2736. ⟨10.1021/acs.jmedchem.7b01312⟩. ⟨inserm-02580381⟩

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