Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

Christophe Guignabert; Carole Phan; Andrei Seferian; Alice Huertas; Ly Tu; Raphaël Thuillet; Caroline Sattler; Morane Le Hiress; yuichi Tamura; Etienne-Marie Jutant; Marie-Camille Chaumais; Stéphane Bouchet; Benjamin Maneglier; Mathieu Molimard; Philippe Rousselot; Olivier Sitbon; Gerald Simonneau; David Montani; Marc Humbert

doi:10.1172/JCI86249

Journal articles

Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

Christophe Guignabert ^{1, 2, 3} Carole Phan ^{1, 2, 3} Andrei Seferian ^{1, 2, 3} Alice Huertas ^{1, 2, 3} Ly Tu ^{1, 2, 3} Raphaël Thuillet ^{1, 2, 3} Caroline Sattler ^{1, 2, 3} Morane Le Hiress ^{1, 2, 3} yuichi Tamura ^{1, 2, 3} Etienne-Marie Jutant ^{1, 2, 3} Marie-Camille Chaumais ^{1, 2, 3} Stéphane Bouchet ^{4, 5} Benjamin Maneglier ⁶ Mathieu Molimard ^{5, 7} Philippe Rousselot ^{8, 9} Olivier Sitbon ^{1, 2, 3} Gerald Simonneau ^{1, 2, 3} David Montani ^{1, 2, 3} Marc Humbert ^{1, 2, 3}

1 INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France

2 Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France

3 AP-HP, Department of Respiratory and Intensive Care Medicine, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.

4 Département de Pharmacologie, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.

5 Université de Bordeaux, INSERM U1219, Bordeaux, France.

6 Service de Biologie Médicale, Centre Hospitalier de Versailles, Le Chesnay, France

7 Département de Pharmacologie, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France

8 Service d’Hématologie et d’Oncologie, Centre Hospitalier de Versailles, Le Chesnay, France

9 UVSQ - Université de Versailles Saint-Quentin-en-Yvelines

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Cellular Biology

Life Sciences [q-bio]

Life Sciences [q-bio] / Human health and pathology / Cardiology and cardiovascular system

Life Sciences [q-bio] / Human health and pathology / Pulmonology and respiratory tract

Complete list of metadata

https://www.hal.inserm.fr/inserm-02579754
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Submitted on : Thursday, May 14, 2020 - 7:47:15 PM
Last modification on : Saturday, February 26, 2022 - 8:30:04 AM

Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

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Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

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