Characterization of four human pregnancy-associated plasma proteins, Am J Obstet Gynecol, vol.118, pp.223-236, 1974. ,
Messenger acid levels of pregnancy associated plasma protein A and the proform of eosinophil major basic protein: expression in human reproductive and non reproductive tissues, Biol Reprod, vol.61, pp.1083-9108, 1999. ,
Identification and regulation of IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation, J Clin Endocrinol Metab, vol.87, pp.1359-1366, 2002. ,
Homodimeric pregnancy-associated plasma protein-A in normal human placenta of first and third trimester of pregnancy: biochemical and morphological observations, Placenta, vol.33, pp.942-945, 2012. ,
Unsal I: Reference interval of pregnancy-associated plasma protein-a in healthy men and non-pregnant women, J Cardiol, vol.61, pp.128-131, 2013. ,
Pregnancy-associated plasma protein A as a marker of acute coronary syndromes, N Engl J Med, vol.345, pp.1022-1029, 2001. ,
Pregnancy-associated plasma protein-A (PAPP-A) and cardiovascular risk, Atherosclerosis, vol.203, pp.346-352, 2009. ,
Circulating human pregnancy-associated plasma protein A is disulfide-bridged to the proform of eosinophil major basic protein, J Biol Chem, vol.268, pp.12243-12246, 1993. ,
Serum PAPP-A in normal pregnancy: relationship to fetal and maternal characteristics, Arch Gynecol, vol.233, pp.211-215, 1983. ,
Biology of pregnancy-associated plasma protein-A in relation to prenatal diagnostics: an overview, Acta Obstet Gynecol Scand, vol.89, pp.1118-1125, 2010. ,
Alton ME: First trimester maternal serum PAPP-A and free-beta subunit human chorionic gonadotropin concentrations and nuchal translucency are associated with obstetric complications: a population-based screening study (the FASTER Trial), Am J Obstet Gynecol, vol.191, pp.1446-1451, 2004. ,
Decreased PAPP-A is associated with preeclampsia, premature delivery and small for gestational age infants but not with placental abruption, Eur J Obstet Gynecol Reprod Biol, vol.157, pp.48-52, 2011. ,
First trimester maternal serum pregnancy-associated plasma protein A and pregnancy-specific ?1-glycoprotein in fetal trisomies, Br J Obstet Gynaecol, vol.101, pp.970-974, 1994. ,
Screening of maternal serum for fetal Down's syndrome in the first trimester, N Engl J Med, vol.338, pp.955-961, 1998. ,
How to improve the screening and diagnosis of fetal aneuploidy?, Bull Acad Med, vol.189, pp.1773-1784, 2005. ,
First trimester maternal serum screening for Down's syndrome: an evaluation of the DPC Immulite 2000 free beta-hCG and pregnancy protein-A assays, Ann Clin Biochem, vol.42, pp.30-40, 2005. ,
Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae, Endocrinology, vol.118, pp.1567-1582, 1986. ,
Evain-Brion D: Retinoid receptors expression in human term placenta: involvement of RXR alpha in retinoid induced-hCG secretion, J Clin Endocrinol Metab, vol.83, pp.1384-1387, 1998. ,
A screening program for trisomy 21 at 10-14 weeks using fetal nuchal translucency, maternal serum free beta-human chorionic gonadotropin and pregnancy associated plasma protein A, Ultrasound Obstet Gynecol, vol.13, pp.231-237, 1999. ,
First trimester detection of structural abnormalities and the role of aneuploidy markers, Ultrasound Obstet Gynecol, vol.339, pp.157-163, 2012. ,
First trimester maternal screening using biochemical markers PAPP-A and free ?-hCG for Down Syndrome, Patau Syndrome and Edward Syndrome, Indian J Clin Biochem, vol.28, pp.3-12, 2013. ,
Secondtrimester ultrasound to detect fetuses with Down syndrome: a metaanalysis, JAMA, vol.85, pp.1044-1055, 2001. ,
Is ultrasound alone enough for prenatal screening of trisomy 18? A single center experience in 69 cases over 10 years, Prenat Diagn, vol.30, pp.1094-1099, 2010. ,
Correlation of prenatal sonographic diagnosis and morphologic findings of fetal autopsy in fetuses with trisomy 21, J Ultrasound Med, vol.26, pp.61-68, 2007. ,
Nuchal tranlucency: screening for chromosomal abnormalities and congenital malformations. Multicenter study, J Gynecol Obstet Biol Reprod, vol.28, pp.538-543, 1999. ,
Screening for fetal anuploidies at 11 to 13 weeks, Prenat Diagn, vol.31, pp.7-15, 2011. ,
Screening for trisomy 18 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation, Prenat Diagn, vol.19, pp.1035-1042, 1999. ,
A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free ß -hCG and PAPP-A, Prenat Diagn, vol.22, pp.877-879, 2002. ,
Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated twostage first-trimester screening, Ultrasound Obstet Gynecol, vol.25, pp.221-226, 2005. ,
Chromosomally abnormal early ongoing pregnancies: correlation of ultrasound and placental histological findings, Hum Pathol, vol.29, pp.1195-1199, 1998. ,
, The placenta and trisomies 13, vol.18, pp.989-996, 1989.
A quantitative analysis of placental vasculature in the third trimester fetus with autosomal trisomy, Obstet Gynecol, vol.75, pp.59-63, 1990. ,
Histomorphological features of chorionic villi at 10-14 weeks of gestation in trisomic and chromosomally normal pregnancies, Placenta, vol.21, pp.678-683, 2000. ,
Trisomy 21 placentas: histopathological and immunohistological finding using proliferating cell nuclear antigen, Fetal Diagn Ther, vol.12, pp.210-215, 1997. ,
Amino acid sequence of human pregnancy-associated plasma protein A derived from cloned cDNA, Biochemistry, vol.33, pp.1592-1598, 1994. ,
Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor, J Biol Chem, vol.275, pp.31128-31133, 2000. ,
Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A, FEBS Lett, vol.504, pp.36-40, 2001. ,
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancyassociated plasma protein A, Proc Natl Acad Sci U S A, vol.96, pp.3149-3153, 1999. ,
Isolation and characterization of circulating complex between human pregnancyassociated plasma protein A and proform of eosinophil major basic protein, Biochim Biophys Acta, vol.1201, pp.415-423, 1994. ,
Amniotic fluid and plasma concentrations of pregnancy-associated plasma protein A (PAPP-A), Br J Obstet Gynaecol, vol.89, pp.701-703, 1982. ,
Measurement of pregnancy associated plasma proteins during human gestation, J Clin Invest, vol.54, pp.576-582, 1974. ,
Pregnancy-associated plasma protein A: circulating levels during normal pregnancy, Am J Obstet Gynecol, vol.139, pp.910-924, 1981. ,
The proform of eosinophil major basic protein: a new maternal serum marker for adverse pregnancy outcome, Prenat Diagn, vol.29, pp.1013-1019, 2009. ,
Immunohistochemical demonstration of pregnancy associated plasma protein A (PAPP-A) in the syncytiotrophoblast of the normal placenta at different gestational ages, Placenta, vol.5, pp.427-431, 1984. ,
Immunohistochemical localization of pregnancy-associated plasma protein A in decidua and trophoblast: comparison with human chorionic gonadotrophin and fibrin, Placenta, vol.5, pp.227-236, 1984. ,
Comparison of different antibody preparations against pregnancy-associated plasma protein A (PAPP-A) for the use in localization and immunoassay studies, Br J Obstet Gynaecol, vol.93, pp.916-923, 1986. ,
Localization of pregnancy-associated plasma protein A and colocalization of pregnancy-associated plasma protein A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta, Lab Invest, vol.71, pp.560-566, 1994. ,
Evain-Brion D: Expression of pregnancy-associated plasma protein-A (PAPP-A) during villous trophoblast differentiation in vitro, Placenta, vol.24, pp.532-539, 2003. ,
Placental size and the prediction of severe early-onset intrauterine growth restriction in women with low pregnancy associated plasma protein A, Ultrasound Obstet Gynecol, vol.34, pp.274-82, 2009. ,
The secretion of PAPP-A, ADAM 12, and PP13 correlates with the size of the placenta for the first month of pregnancy, Placenta, vol.32, pp.999-1003, 2011. ,
First trimester serum analytes, biophysical tests and the association with pathological morphometry in the placenta of pregnancies with preeclampsia and fetal growth restriction, Placenta, vol.32, pp.333-338, 2011. ,
Evain-Brion D: Defect of villous cytotrophoblast differentiation into syncytiotrophoblast in Down's syndrome, J Clin Endocrinol Metab, vol.85, pp.3700-3707, 2000. ,
Evain-Brion D: Trophoblast production of a weakly bioactive human chorionic gonadotropin in Trisomy 21-affected pregnancy, J Clin Endocrinol Metab, vol.89, pp.727-732, 2004. ,
Modulation of PAPP-A expression by PPAR ? in human first trimester trophoblast, Placenta, vol.27, pp.127-134, 2006. ,
Trophoblast proliferation is increased in chorionoic villi from pregnancies with fetal trisomy 18, Placenta, vol.21, pp.584-586, 2000. ,
Trisomy 21 is associated with variable defects in cytotrophoblast differentiation along the invasive pathway, Am J Med Genet, vol.130, pp.354-364, 2004. ,
Maternal serum ADAM 12 (A disintegrin and metalloprotease) in chromosomally abnormal pregnancy at 11-13 weeks, Am J Obstet Gynecol, vol.200, pp.1-6, 2009. ,
Evain-Brion D: Human trophoblast fusion and differentiation : lessons from trisomy 21 placenta, Placenta, vol.33, pp.81-86, 2012. ,
An integrative view on the physiology of human early placental villi, Prog Biophys Mol Biol, vol.114, pp.33-48, 2014. ,
Pattern of secretion of pregnancyassociated plasma protein-A (PAPP-A) during pregnancies complicated by fetal aneuploidy, in vivo and in vitro, Reproductive Biology and Endocrinology, vol.12, p.129, 2014. ,
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