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Type 1 interferons as a potential treatment against COVID-19

Abstract : Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.
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https://www.hal.inserm.fr/inserm-02546137
Contributor : Myriam Bodescot <>
Submitted on : Friday, April 17, 2020 - 5:05:14 PM
Last modification on : Sunday, April 19, 2020 - 1:34:05 AM

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Erwan Sallard, François-Xavier Lescure, Yazdan Yazdanpanah, France Mentré, Nathan Peiffer-Smadja. Type 1 interferons as a potential treatment against COVID-19. Antiviral Research, Elsevier Masson, 2020, 178, pp.104791. ⟨10.1016/j.antiviral.2020.104791⟩. ⟨inserm-02546137⟩

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