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Switch hitter: Bcl11b in T cells and ILC2s

Abstract : In this issue of JEM, Hosokawa et al. (https://doi-org.proxy.insermbiblio.inist.fr/10.1084/jem.20190972) establish that transcription factor Bcl11b regulates almost completely distinct sets of genes in T cell precursors and ILC2s. To understand how this occurs, they identify multiple levels of functional regulation for Bcl11b that are used differently by T cell precursors and ILC2s.
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https://www.hal.inserm.fr/inserm-02541576
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Submitted on : Tuesday, April 14, 2020 - 7:58:43 AM
Last modification on : Wednesday, April 15, 2020 - 1:46:26 AM

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Christelle Harly, Avinash Bhandoola. Switch hitter: Bcl11b in T cells and ILC2s. The Journal of Experimental Medecine, The Rockefeller University Press, 2020, 217 (1), pp.e20191739. ⟨10.1084/jem.20191739⟩. ⟨inserm-02541576⟩

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