, Genetics of gene expression and its effect on disease, Nature, vol.452, issue.7186, p.423, 2008.
, Disease signatures are robust across tissues and experiments, Molecular Systems Biology, vol.5, issue.1, p.307, 2009.
, Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients, Nature Communications, vol.5, p.4022, 2014.
, The human disease network, Proceedings of the National Academy of Sciences, vol.104, issue.21, pp.8685-8690, 2007.
, The implications of human metabolic network topology for disease comorbidity. Proceedings of the National Academy of Sciences, 2008.
, Robust biomarker identification for cancer diagnosis with ensemble feature selection methods, Bioinformatics, vol.26, issue.3, pp.392-398, 2009.
, Stable feature selection for biomarker discovery, Computational Biology and Chemistry, vol.34, issue.4, pp.215-225, 2010.
, Ranking candidate disease genes from gene expression and protein interaction: a Katzcentrality based approach, PLoS One, vol.6, issue.9, p.24306, 2011.
, Identifying disease-associated pathways in one-phenotype data based on reversal gene expression orderings, Scientific Reports, vol.7, issue.1, p.28465555, 2017.
, Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways, Journal of Alzheimer's Disease, vol.14, issue.1, pp.27-41, 2008.
, Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies Scientific Reports, vol.7, p.43946, 2017.
, A dynamic network approach for the study of human phenotypes, PLoS Computational Biology, vol.5, issue.4, 2009.
, Conditional disease development extracted from longitudinal health care cohort data using layered network construction, Scientific Reports, vol.6, p.26170, 2016.
, PCID: A novel approach for predicting disease comorbidity by integrating multi-scale data, IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol.14, issue.3, pp.678-686, 2017.
, Unveiling the molecular basis of disease co-occurrence: towards personalized comorbidity profiles. bioRxiv, 2018.
, Machine Learning for Biomedicine. Cell, vol.173, issue.7, pp.1562-1565, 2018.
, Using deep learning to model the hierarchical structure and function of a cell, Nature Methods, vol.15, issue.4, p.290, 2018.
, Gene Ontology: tool for the unification of biology, Nature Genetics, vol.25, issue.1, p.25, 2000.
, The Reactome Pathway Knowledgebase, Nucleic Acids Research, vol.46, issue.D1, pp.649-655, 2018.
, Deep learning, vol.1, 2016.
, A method for stochastic optimization, 2014.
, Delving deep into rectifiers: Surpassing human-level performance on imagenet classification, Proceedings of the IEEE international Conference on Computer Vision, pp.1026-1034, 2015.
, A System for Large-Scale Machine Learning, 12th USENIX Symposium on Operating Systems Design and Implementation (OSDI 16), pp.265-283, 2016.
, Sensitivity analysis for minimization of input data dimension for feedforward neural network, Proceedings of IEEE International Symposium on Circuits and Systems-ISCAS'94, vol.6, pp.447-450, 1994.
, DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants, Nucleic Acids Research, vol.45, issue.D1, pp.833-839, 2017.
, Scikit-learn: Machine Learning in Python, Journal of Machine Learning Research, vol.12, pp.2825-2830, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00650905
, Schizophrenia and infections: the eyes have it, Schizophrenia Bulletin, vol.43, issue.2, pp.247-252, 2017.
, The spectrum of thyroid disease and risk of new onset atrial fibrillation: a large population cohort study, British Medical Journal, vol.345, p.7895, 2012.
, Comorbidities in vitiligo: comprehensive review, International Journal of Fermatology, vol.57, issue.10, pp.1157-1164, 2018.
, Adverse outcomes in patients with atrial fibrillation and peripheral arterial disease: a report from the EURObservational research programme pilot survey on atrial fibrillation, Ep Europace, vol.19, issue.9, pp.1439-1448, 2016.
, Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus, Journal of Gastroenterology and Hepatology, vol.27, p.22320911, 2012.
, Disulfiram reduces metastatic osteosarcoma tumor burden in an immunocompetent Balb/c or-thotopic mouse model, Oncotarget, vol.9, issue.53, p.30163, 2018.
, Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study, The American Journal of Surgical Pathology, vol.22, issue.9, pp.1083-1092, 1998.
, Non-segmental vitiligo and psoriasis comorbidity-a case-control study in Italian patients, Journal of the European Academy of Dermatology and Venereology, vol.28, issue.4, pp.433-437, 2014.
, Right ventricular failure due to primary right ventricle osteosarcoma, General Thoracic and Cardiovascular Surgery, vol.55, issue.1, p.17444167, 2007.
, Primary right atrial cardiac osteosarcoma with congestive heart failure, European Journal of Cardio-Thoracic Surgery, vol.35, issue.3, pp.544-546, 2009.
, Progressive visceral leishmaniasis misdiagnosed as cirrhosis of the liver: a case report, Journal of Medical Case Reports, vol.3, issue.1, p.7265, 2009.
, Pseudoacromegaly: a differential diagnostic problem for acromegaly with a genetic solution, Journal of the Endocrine Society, vol.1, issue.8, pp.1104-1109, 2017.
, Osteosarcoma as a second tumor after treatment for primary non-Hodgkin's lymphoma in a child with ataxia-telangiectasia: presentation of a case and review of possible pathogenetic mechanisms, Journal of Pediatric Hematology/Oncology, vol.26, issue.7, pp.444-446, 2004.
, miR-202 suppresses proliferation and induces apoptosis of osteosarcoma cells by downregulating Gli2, Molecular and Cellular Biochemistry, vol.397, issue.1-2, p.25156120, 2014.