An apoptosis-inhibiting baculovirus gene with a zinc finger-like 2. Inohara, N.; Nunez, G. Genes with homology to mammalian apoptosis regulators, p.32 ,
Interaction of checkpoint kinase 1 and the X-linked inhibitor 105 ,
, , vol.121
, Structural basis of IAP recognition by 122
,
Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions 136 ,
Advances in IKBKE as a potential target for cancer therapy, Cancer Med, p.1070, 2020. ,
Frequent engagement of the classical and alternative NF-kappaB pathways 1071 by diverse genetic abnormalities in multiple myeloma, Cancer Cell, vol.12, p.140, 1072. ,
, , p.1074
Promiscuous mutations activate the noncanonical NF-kappaB pathway in 1075 multiple myeloma, Cancer Cell, vol.12, pp.131-144, 2007. ,
, , p.1077
Noncanonical NF-kappaB activation requires coordinated assembly of a 1078 regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK, Nature, vol.9, p.142, 1079. ,
RIP kinases as modulators of inflammation and immunity, Nat Immunol, vol.19, pp.912-922, 2018. ,
A critical role 1083 of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation, EMBO J, vol.27, p.144, 1084. ,
Activation of IKK by TNFalpha requires site-specific 1086 ubiquitination of RIP1 and polyubiquitin binding by NEMO, Mol Cell, vol.22, p.145, 1087. ,
Ubiquitination of RIP1 1089 regulates an NF-kappaB-independent cell-death switch in TNF signaling. Current biology : CB, vol.17, p.146, 2007. ,
Rip1 mediates the Trif-1092 dependent toll-like receptor 3-and 4-induced NF-{kappa}B activation but does not contribute to 1093 interferon regulatory factor 3 activation, J Biol Chem, vol.280, p.147, 2005. ,
Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer, Trends Mol Med, vol.24, p.148, 2018. ,
Lys63/Met1-hybrid 1097 ubiquitin chains are commonly formed during the activation of innate immune signalling, Biochem, vol.1098 ,
, Biophys Res Commun, vol.474, p.149, 2016.
Receptor interacting protein is ubiquitinated by cellular inhibitor of 151, vol.150 ,
, Cellular IAP proteins, vol.152, p.153
, , p.1113
The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate 1114 TNFR2-induced canonical NF-?B signaling, Biochem Pharmacol, vol.153, p.154, 1115. ,
, , p.155
A small molecule Smac 1120 mimic potentiates TRAIL-and TNFalpha-mediated cell death, Science, vol.305, pp.1471-1474, 1121. ,
, Autocrine Cell, vol.12, pp.445-456, 2007.
, , vol.18, p.159, 2011.
, , p.1133
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing 1134 intracellular cell death complex differentially regulated by cFLIP isoforms, Mol Cell, vol.43, issue.11, p.160, 1135. ,
, , p.1137
RIPK1 promotes death receptor-independent caspase-8-mediated 1138 apoptosis under unresolved ER stress conditions, Cell Death Dis, vol.5, 1139. ,
Sad, S. cIAP1 and cIAP2 limit 1141 macrophage necroptosis by inhibiting Rip1 and Rip3 activation, Cell Death Differ, vol.19, pp.1791-1801, 1142. ,
, , vol.164
Activity of protein kinase RIPK3 determines whether 1154 cells die by necroptosis or apoptosis, Science, vol.343, p.166, 2014. ,
, , vol.167
, , p.1159
XIAP Loss Triggers RIPK3-and Caspase-8-Driven IL-1? Activation and Cell Death 1160 as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation, Cell Rep, vol.20, p.168, 1161. ,
, , p.1163
XIAP restricts TNF-and RIP3-dependent cell death and 1164 inflammasome activation, Cell Rep, vol.7, p.169, 2014. ,
, , p.1166
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in 1167 inflammation and innate immunity, Mol Cell, vol.46, issue.12, pp.310-313, 2012. ,
, Cell Rep, vol.14, p.171, 2016.
,
, , vol.14529, p.174
XIAP regulates cytosol-specific innate immunity to Listeria 175 ,
, , vol.176
, XIAP controls, p.2
,
TNF-alpha induced c-IAP1/TRAF2 1197 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination, Embo J, vol.24, p.180, 2005. ,
, , p.181
Beyaert, R. TRAF2 multitasking in TNF receptor-induced signaling to NF-183 ,
, , p.1208
Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-1209 triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING 1210 dimerization and E2 binding, J Biol Chem, vol.285, pp.17525-17536, 2010. ,
, , vol.185
, TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through 1217 NF-?B Activation in Human Macrophages, vol.200, pp.1593-1606, 1218.
The role of the transcription factor CREB in immune function ,
K63-linked polyubiquitination of transcription factor IRF1 1223 is essential for IL-1-induced production of chemokines CXCL10 and CCL5, Nature immunology, vol.15, p.188, 2014. ,
Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation, Int J Mol Sci, vol.18, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01632423
,
A role for Drosophila IAP1-mediated caspase inhibition in Rac-192 ,
,
,
(87) to suppress apoptotic cell death, Psychogeriatrics, vol.11, pp.90-97, 0196. ,
Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell 1250 death, J Cell Sci, vol.130, pp.502-511, 2017. ,
Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with 1257 cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation, Cell Death Differ, vol.15, pp.1258-859, 2008. ,
,
Inhibitor of apoptosis proteins in human health and disease, Genes Immun, 2019. ,