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Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report

Abstract : BACKGROUND: Yellow fever vaccine exists for over 80 years and is considered to be relatively safe. However, in rare cases it can produce serious neurotropic and viscerotropic complications. We report a case of a patient who presented both viscerotropic and neurological manifestations after yellow fever vaccination. CASE PRESENTATION: We describe the case of a 37 years old man who developed after the yellow fever vaccination a yellow fever vaccine-associated viscerotropic disease followed by acute uveitis. Prolonged detection of yellow fever RNA in blood and urine was consistent with yellow fever vaccine-associated adverse event. The final outcome was good, although with persistent fatigue over a few months. CONCLUSIONS: Even if the yellow fever vaccine is relatively safe, physicians should be aware of its possible serious adverse effects.
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Submitted on : Friday, March 20, 2020 - 3:39:18 PM
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Lev Volkov, Gilda Grard, Pierre-Edouard Bollaert, Guillaume Durand, Aurélie Cravoisy, et al.. Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report. BMC Infectious Diseases, BioMed Central, 2020, 20 (1), pp.116. ⟨10.1186/s12879-020-4838-x⟩. ⟨inserm-02513378⟩

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